ID K7WN35_9NOST Unreviewed; 208 AA.
AC K7WN35;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Precorrin-8X methylmutase {ECO:0000313|EMBL:AFW96978.1};
DE EC=5.4.1.2 {ECO:0000313|EMBL:AFW96978.1};
GN Name=cobH {ECO:0000313|EMBL:AFW96978.1};
GN ORFNames=ANA_C20544 {ECO:0000313|EMBL:AFW96978.1};
OS Anabaena sp. 90.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Anabaena.
OX NCBI_TaxID=46234 {ECO:0000313|EMBL:AFW96978.1, ECO:0000313|Proteomes:UP000010101};
RN [1] {ECO:0000313|EMBL:AFW96978.1, ECO:0000313|Proteomes:UP000010101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=90 {ECO:0000313|EMBL:AFW96978.1};
RX PubMed=23148582; DOI=10.1186/1471-2164-13-613;
RA Wang H., Sivonen K., Rouhiainen L., Fewer D.P., Lyra C., Rantala-Ylinen A.,
RA Vestola J., Jokela J., Rantasarkka K., Li Z., Liu B.;
RT "Genome-derived insights into the biology of the hepatotoxic bloom-forming
RT cyanobacterium Anabaena sp. strain 90.";
RL BMC Genomics 13:613-613(2012).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; CP003285; AFW96978.1; -; Genomic_DNA.
DR RefSeq; WP_015083531.1; NC_019439.1.
DR AlphaFoldDB; K7WN35; -.
DR STRING; 46234.ANA_C20544; -.
DR KEGG; anb:ANA_C20544; -.
DR PATRIC; fig|46234.3.peg.4958; -.
DR eggNOG; COG2082; Bacteria.
DR HOGENOM; CLU_084703_0_0_3; -.
DR OrthoDB; 9780708at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000010101; Chromosome chANA02.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:AFW96978.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010101}.
FT DOMAIN 10..205
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 208 AA; 22633 MW; FA2A6DDFF85033F3 CRC64;
MFDYIRDGNE IYRNSFAIIR SESNLERFPE DVAKVAVRMI HACGMTDIVN DLEYSSTAVE
AGKKALIGGS LILCDSYMVA EGVTRKRLPK NNKVLCTLND PEVPQLAKRL RNTRSAAALE
FWRFHIEGAI VVIGNAPTAL FRLLEMLDEG IPRPALILGF PVGFVGAVES KVALAADSRN
VPFMTLHGRR GGSAIAAAAV NALASEEE
//
