ID K7XY37_RCMVE Unreviewed; 284 AA.
AC K7XY37;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=B127 {ECO:0000313|EMBL:AKB93314.1};
DE SubName: Full=E127 {ECO:0000313|EMBL:AFX83435.1};
GN Name=e127 {ECO:0000313|EMBL:AFX83435.1};
GN Synonyms=b127 {ECO:0000313|EMBL:AKB93314.1};
OS Rat cytomegalovirus (isolate England) (RCMV-E) (Murid herpesvirus 8).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Orthoherpesviridae; Betaherpesvirinae; Muromegalovirus;
OC Muromegalovirus muridbeta8.
OX NCBI_TaxID=1261657 {ECO:0000313|EMBL:AFX83435.1, ECO:0000313|Proteomes:UP000127637};
OH NCBI_TaxID=10116; Rattus norvegicus (Rat).
RN [1] {ECO:0000313|Proteomes:UP000097765, ECO:0000313|Proteomes:UP000127637}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berlin {ECO:0000313|EMBL:AKB93314.1}, and England
RC {ECO:0000313|EMBL:AFX83435.1};
RX PubMed=23166247; DOI=10.1128/JVI.02614-12;
RA Ettinger J., Geyer H., Nitsche A., Zimmermann A., Brune W., Sandford G.R.,
RA Hayward G.S., Voigt S.;
RT "Complete genome sequence of the english isolate of rat cytomegalovirus
RT (Murid herpesvirus 8).";
RL J. Virol. 86:13838-13838(2012).
RN [2] {ECO:0000313|Proteomes:UP000097765, ECO:0000313|Proteomes:UP000127637}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berlin {ECO:0000313|EMBL:AKB93314.1}, and England
RC {ECO:0000313|EMBL:AFX83435.1};
RX PubMed=26209537; DOI=.1099/vir.0.000109;
RA Geyer H., Ettinger J., Moller L., Schmolz E., Nitsche A., Brune W.,
RA Heaggans S., Sandford G.R., Hayward G.S., Voigt S.;
RT "The English isolate and a newly identified Berlin isolate of Rat
RT Cytomegalovirus (RCMV) share similarities with but separate as an anciently
RT diverged clade from Mouse CMV and the Maastricht isolate of RCMV.";
RL J. Gen. Virol. 96:1873-1882(2015).
RN [3] {ECO:0000313|EMBL:AFX83435.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=England {ECO:0000313|EMBL:AFX83435.1};
RA Heaggans S.Y., Hayward G.S.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JX867617; AFX83435.1; -; Genomic_DNA.
DR EMBL; KP202868; AKB93314.1; -; Genomic_DNA.
DR RefSeq; YP_007016518.1; NC_019559.1.
DR GeneID; 14039041; -.
DR KEGG; vg:14039041; -.
DR OrthoDB; 11236at10239; -.
DR Proteomes; UP000097765; Genome.
DR Proteomes; UP000127637; Genome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0098632; F:cell-cell adhesion mediator activity; IEA:InterPro.
DR GO; GO:0043031; P:negative regulation of macrophage activation; IEA:InterPro.
DR GO; GO:0050776; P:regulation of immune response; IEA:InterPro.
DR CDD; cd05846; IgV_1_MRC-OX-2_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR033321; CD200_Ig_V_dom.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR047164; OX2G-like.
DR PANTHER; PTHR46841; OX-2 MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR46841:SF3; OX-2 MEMBRANE GLYCOPROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF00047; ig; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000127637};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 242..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..127
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 132..217
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 284 AA; 31840 MW; 9C686B7971097558 CRC64;
MNLMFILFYI IISINPTLSQ VEVVTQDVNS SLRSPASLRC SLKTTQEPLI VTWQKKKAVG
PENMATYSKA HGVVLQPTYK DRINITELGL LNSSITFWNA TLDDEGCYMC LFNMFGSGKV
SGTSCLTLRY TPSVFISGNL SDNILNVTCS AVSRPNVSIT WVPLGDGLKN FTTSQSQSDG
TTKVTSVLYG NLTLHNKNVT CRIIYLNTVY NYSVVLDGFY PTPPTSPVSF TSDNSTRTTR
TILLLIIIFM ILTTVIALLY WRKQRYSRLM RFYRRSVVPL CPKL
//
