ID K7YJ43_9PROT Unreviewed; 5014 AA.
AC K7YJ43;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=PtzC {ECO:0000313|EMBL:AFX99665.1};
GN ORFNames=A1OE_1496 {ECO:0000313|EMBL:AFX99665.1};
OS Candidatus Endolissoclinum faulkneri L2.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Rhodospirillaceae; Endolissoclinum.
OX NCBI_TaxID=1193729 {ECO:0000313|EMBL:AFX99665.1, ECO:0000313|Proteomes:UP000010077};
RN [1] {ECO:0000313|EMBL:AFX99665.1, ECO:0000313|Proteomes:UP000010077}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2 {ECO:0000313|EMBL:AFX99665.1,
RC ECO:0000313|Proteomes:UP000010077};
RX PubMed=23185008; DOI=10.1073/pnas.1213820109;
RA Kwan J.C., Donia M.S., Han A.W., Hirose E., Haygood M.G., Schmidt E.W.;
RT "Genome streamlining and chemical defense in a coral reef symbiosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:20655-20660(2012).
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DR EMBL; CP003539; AFX99665.1; -; Genomic_DNA.
DR RefSeq; WP_015089163.1; NC_019566.1.
DR STRING; 1193729.A1OE_1496; -.
DR KEGG; thal:A1OE_1496; -.
DR PATRIC; fig|1193729.4.peg.784; -.
DR eggNOG; COG0236; Bacteria.
DR eggNOG; COG0300; Bacteria.
DR eggNOG; COG2227; Bacteria.
DR eggNOG; COG3321; Bacteria.
DR eggNOG; COG4221; Bacteria.
DR HOGENOM; CLU_000022_58_0_5; -.
DR Proteomes; UP000010077; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 2.
DR CDD; cd00833; PKS; 3.
DR Gene3D; 1.10.1240.100; -; 3.
DR Gene3D; 3.10.129.120; -; 1.
DR Gene3D; 3.40.47.10; -; 3.
DR Gene3D; 1.10.1200.10; ACP-like; 4.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 3.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 2.
DR Pfam; PF00109; ketoacyl-synt; 3.
DR Pfam; PF02801; Ketoacyl-synt_C; 3.
DR Pfam; PF08659; KR; 3.
DR Pfam; PF08242; Methyltransf_12; 2.
DR Pfam; PF00550; PP-binding; 4.
DR Pfam; PF14765; PS-DH; 3.
DR SMART; SM00822; PKS_KR; 2.
DR SMART; SM00825; PKS_KS; 3.
DR SMART; SM00823; PKS_PP; 4.
DR SMART; SM01294; PKS_PP_betabranch; 3.
DR SUPFAM; SSF47336; ACP-like; 4.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 3.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
DR SUPFAM; SSF53901; Thiolase-like; 3.
DR PROSITE; PS50075; CARRIER; 4.
DR PROSITE; PS00606; KS3_1; 3.
DR PROSITE; PS52004; KS3_2; 3.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 29..106
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 126..546
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1766..1840
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1875..2295
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 3113..3189
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3232..3660
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 4840..4917
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 5014 AA; 535677 MW; C0C2671BEBBC18CB CRC64;
MISYRDRRIE LDKAKYTDAD GFIHLKQDVD EVDLKSVLLG IVSKVLGEKI DAEKAVRSFA
DLGLGSLLSV RLIEEINRAY GLKLGVETVF AHPNPSALVN HVASMIDKHA MPTIISSQKE
SSFNNRGAVA IIGISGAFGS TSSLSAFSDA LMHCESLVHP LSNQRRRLVR PLLGNDNSTF
VGGFLKDIEL FDAELFGLSP REASAIDPQQ RLFLERAYLA LENAGYPAAR IAGKKVGVYV
GASPSGYEQL IESDDGAGDA WGMTGNLTAL LASRISYYLD LGGPALTVDT ACSSSLVALD
LAIQGIKNGD CDMALVGGVS LFLNPISLTL MKRAGMQSKQ GRCATFDASA DGIVVGEAVV
AAVLKPFEQS LIDGDRIDAV VLSTAINQDG RSNGITAPNS TAQTNLICAA LDRAGLDADA
IDVIEAHGTG TPLGDPVEIA GLFGAFRKRS KGLPAICLGS AKSVLGHASE AAGLVGVANI
VAALKAESIP PIFGFTDLNP RIDLSGKPLK VTSAKKVWPR IAGHTRRAGV NSFGLAGTNA
HAIIAEGPSV VSESSLSGSF PLLLSAENLD LLAKRAKSLL GWLKGKNISL IDFVGTLALR
RSHYSVRAGA IVTSLDEVCG VLAELDQYKL PSICTDPVVL DYLKRGENWI DSCNNLFGNK
IICLDLPDQP LAHESLWAFA LDATESTRLS LSIEDPKVGD HRVGNQSILH AAALLDIVLD
QFGNKINEIA WLRPVIVGKE GAVLILNGGG KSSGLATVEG GENVFSFGAS GSPDTINKRV
EFSELLAIQA AAVNKIDGGV SEPAPGVWLG PTYRGFDRLS IAPNAAVGSV DLSNSSFPRL
RALDAAIQSA VALVASRDGD ATCTRMPVRM HELSVLMPIP PLTMHLLAYF NNELSCGVES
VVDVSVVGDD GTIAMQLNGL TLHAIDSANQ TPVVQQKDPS VCLRQLVWQE YCTSALGGID
LRPTLIIGNG DLLDRVSDCL ICSGNVVTRK QALASLAVTE WLADTEGVRR IVLYLPADYS
SNTLDRGACC IRSIACSLTT LEAPLDFLIL APGAKDDPVR RALIALAKVS LDKEIDKVTV
RTIDCDNDTA IELLLTEPGT SSGEMVVLTN GKRFEQRLKE IIVDRKADNF GRRIVILGGF
GRVGRVLANR IAECWKANIV LVGRKEISKE RAAYMETLRA KGVQVYGLSI DLTDSLAAEI
ALCTARDKLG GIDLVIQAVV DPVFGRLSAM PESDMLSGLR AKTTGGMAVK SALEAIGEGR
LVVVSSIGAF AGFPGAAGQA VYAAQCAFES VLADATTQVV HWGLWADPSW RPELLAQVRK
DGLFPMPEDA AFDAFESALS LQCDTPLVAA SLSASVWRAL GDVDHLDPAL GEPVNFIDQV
SNLANTLLGD SLERHVAVES IANRRLLCVM KKNGLLGLPG KEENLTQAII RFGAPSRLNK
LAHAILNLLI AAGAAERCSN GYIRWCETIF DDKDGLEEFA ACDEISKAVA FLMADCIDAL
PKILSGELRG TDVLFPEGSV AKVEPIYKHQ PGLKAANVLV AEIVASLYNR SNSLSVLEIG
AGTGATTEAI RLRLGNAVEG LSYCYTDVSV GFVRHGEKFH STPSLTSALL DIEQDPIEQG
FIEQSFDVVV ASNVLHATTK LDDTLIHVWK LLRPGGILIL NENVRLETFA TLTFGLLEGW
WRSEDPQKRL ADGPLLDLAR WRLVLSQAGL DVIAELAPGN VPNHASQVVI VSLKAGVESA
GFVAPVSSKP IVSASSVDSV TSFKESGLQD TVRQVVAEAL GRAADSIDDS LPFADYGVDS
IVSPQIAQSL AERFQVTLRS TDLFSYATVD VLSKHIKSLG PIIPDTKPGD IVQSTDTPTF
STPLPSLVSN SPKFDRRIAI IGLAGRFPDA PDVSVFWHNL RDGHCAIRPI KRFFIPETFD
VGCDTPTPIY ARWAGLIDDF DQFDPLFFKI TPSEALTMDP QQRLLLEEAW HAIEDAGLSP
DRIVGGRTGV FVGSSANSYV APGTPAMQTI GGSMAILSAR LAYLLDLRGP TFPIDTGCSS
SLVALSLARD SLLADQCDLA IVAGVGCNLL SEDILAYLSD AGMASPNGVC YAFDDRANGF
VPGEGVGVLI LKRLADAEND NDRIRALILG AGINQDGRTS GITAPSASSQ TALVRRVWKE
ANVSAESITL VEAHGTGTRL GDPIEVAALN DAFAAETSKR HFCAIGSVKT NIGHAMAAAG
LAGLIKTVLA LENRAIPGSL FFEKANRHID FDSSPLVVAR KTMPWSIDGI IGGRRRAGVS
SFGFSGTNAH VVLEEAPEMV INDDNIPGPW IFVISAKTNE ALNKIALALA SHIEQTNDRL
GDIAYTLALR REHFRCRRVV IAAKRDELTK ALRLVTDKVY SNEIPNFSTS IPKILRDAEI
DYLAGNIVDF TLCFPGNSWR LVSLPGYPFA RERYWQPIRR EAVQASSVVD PQLIVDGNTV
TIILAATNWR LDQHRVHGRP MLPAAAMVEL IGLAIMAKNE SLPHCLADLV WHRPVNVEGN
NLLLTLVMNG DEFRMNRGDV LVVEGRVDSF TYQSQVIDTT DFTGTKIDGS YLLSISKARG
IAYGERFAIL SQIYVGEGMA LARLSPNVQA TCRTADIIDA AMQAAAGVGL GGEKDNSGSP
SGLYVPHALG RIVWLTDEKS SPVHVLATVL RRDVSGALFD ITIANENGQV LAKMDKLVAR
RMEGNNNELC LTTLHAPRWI SADERGSPML DRIVKVSHNW LDSLGDLAAG TRLGVIVKLP
AIEYGKLALA KLSLIVRGLS ALPSAPIVHL MAILDGDSEA PFVRAVAAAL RAVLVENVGW
RLALVSGRVN DTQLPTFPSV AYVEDLRITS DDRLERRILH DLGSITTKSS SPLSSDSVVV
ISGGLGGLGC ELASVLSRAG LKPVLLSRRS GQAEVPVVVA DVTDKDALEG ALATIRNDFG
PITAVLHLAG KQLDGIFSTV TSTDIDEVFA AKVTGFITLD DATRSDPIKL FAVFGSTAAE
FGSFGQGVYG AANAAVASLA ANRPGPGNTL CVAWPLWKSG GMTVPDDLVN MLKREAGLEP
LSTELGVNAL WNAAHSGEVT PLVLHGIGDV AAGLMRLSTS ITPMALPEMQ DATPPIDAIG
YIASILSEVA AIPLNRIDPE LPFEQYGIDS MMITRLNLAM ERDLGALPKT LFFEYRTPGE
IANYLSHNKA SELATIFKPT RLPISSQTTT LPQTSKFNSD TSTIPYLVDR EDTEVAIIGI
AGIFPGAEDL EVFWEHLRSN TDLIREIPID RWPLEGFYDP DRENISTSYS KWGGFIEGAE
MFDPLFFDMA PVEAEALDPQ ARKMLEVSWW ALEDAGYTRS NLFSSDPNPS LRKGGVFVGL
MHSDYQLFAA ESRVRGELAI TSSGYWNAAN RISHFLNLHG PSVAIDTACS ASLTAIYSAL
RALAAGDCTV AIAGGVNLSL HPMKYWVLSK AGFASTDGRC RSFGEGGNGY VPGEGAGAVV
LKPLSRAKAD GDRIHGVIRA SAVNHGGRTS GFTVPNPVAQ GQLISDAFKR AGIAPSSVSY
VEAHGTGTAL GDPIEINGLK RSFGNVVDCP IGSVKSNIGH LESAAGIAAL TKVLLQMRHR
TLAPSLHANT LNPDLGIEGS GFRVVTKAEP WKPPSDGAPL RAGISSFGAG GSNAHLIVDA
PPFLNRKIIK HEALPFPLSA RTSNLLKVVA GQLAKFVENS DASLADISFT LVEGREAMKQ
RAVVVAADRV TLIAGLWLIA EGKDINDFGF FDSQCSAWIK GESVDWRTVL PEGAGRIGLP
LTPFERRRCW ISTRHDPAFN GLDTIHEVCQ VDDPLIVDHV VEGKTIAAGA LLISEAVRKL
GLKFPFTLSD VSWRHTVTVS SEGLLVNPQR EDNHVSILVG SHDDVVASFT ISNVVVVPNR
ETIPVTRRTI KSSEFYSMLA TAGVVYGSSF ARIKNLSTNA GVAVGDLSQP TDASRGLLDS
RILDAALQAC AGIIEKDGSG LRPASIGKLN VWRALSDAVQ VVVRRRGAGD PLMADISLFD
GSGETVATLD RLVLLPTASV ANYGPPLRLL RPTKVQITAL PARLRAGSVI IVDPYFLRGL
ADALVSKLKA DDNVVYLTDV LTEKMPDNLT EIVYLGGVGG KGTDGVLALM RLCKTLAANR
ITKDRLLLRV VVEDTPSGAA VTAFAKALSR EMEWLQLCLI CLPVASQPKQ AAEWINVTPD
APQDAEISVH DGIYSRLVLN EIQSTAAESS IVANGRYLIA GGSGGIGRAL GRHLAETQGA
TVWLIGRRPL TVDEQASIAD LTYGKISYIQ ADITDIASMS VALSDIRSGG ALDGIIHAAL
VMEDKLVVDQ TEFEVERILA PKTRGIDALM ATFDGIKVNS WIAFSSSNAY TANQGQAAYA
AASAYLDASV LATGKNARVI DWGLWGDIGR MAGDPRTAGL KRMGVWPIAT AEGFAAFKSI
LAGRDRRVLA MKLVDTLLPA LGVEARSSVT PLVEAMEEMT QNEPPVAAFD SSPLQAVDAY
AIASLAEYLD GVPSMMPIPE MQRLANAIDI LRMEATGSAE EMKRRVEAAG KGTTPYVVLL
DHALPHLREV VEGSITAASI LFPDGSDRLV APIYKGNPLI DWLQRLAARA VAAAVQDKLI
RDPSRPIRVV EIGAGTAGTT GFVLEEIAPF INQGVSYTFT DIGPSFLVAA RRQFADIPNF
EVKLLDVSRS VADQGFDNAS VDVVLAANVV HATPCIAETL SNIAQLLTHD GVLVLKEATG
IHAINTLTFG LTAEWWGYSD PQSRMSGGPL LSRAGWRLAL TEVGYRNISI AGLPGDIDGL
GAESVIVSVA SNVARVAIKA LPQEEKVVRS SNLSQVKAGE VHSSIENKLI ASVAEALHLD
PNEIDLSASF ADYGADSIIS VELVRKINES FGIELKTTAL FNFATVRDLA RYITLEFGDQ
SVLQQAVLND KDELVVRVDE TRSRTNRLRE IIDRRRTAAP VNAEADFLAR EAQNVVDTNQ
EKLSAMSMEN LLKSLEVGEI DLKKAYEIEI SKDV
//
