ID K7YNX4_9PROT Unreviewed; 447 AA.
AC K7YNX4;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=tRNA synthetases class I (E and Q), catalytic domain protein {ECO:0000313|EMBL:AFX98309.1};
GN ORFNames=A1OE_98 {ECO:0000313|EMBL:AFX98309.1};
OS Candidatus Endolissoclinum faulkneri L2.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Rhodospirillaceae; Endolissoclinum.
OX NCBI_TaxID=1193729 {ECO:0000313|EMBL:AFX98309.1, ECO:0000313|Proteomes:UP000010077};
RN [1] {ECO:0000313|EMBL:AFX98309.1, ECO:0000313|Proteomes:UP000010077}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2 {ECO:0000313|EMBL:AFX98309.1,
RC ECO:0000313|Proteomes:UP000010077};
RX PubMed=23185008; DOI=10.1073/pnas.1213820109;
RA Kwan J.C., Donia M.S., Han A.W., Hirose E., Haygood M.G., Schmidt E.W.;
RT "Genome streamlining and chemical defense in a coral reef symbiosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:20655-20660(2012).
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC Glutamate--tRNA ligase type 1 subfamily.
CC {ECO:0000256|ARBA:ARBA00007894}.
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DR EMBL; CP003539; AFX98309.1; -; Genomic_DNA.
DR RefSeq; WP_015087807.1; NC_019566.1.
DR AlphaFoldDB; K7YNX4; -.
DR STRING; 1193729.A1OE_98; -.
DR KEGG; thal:A1OE_98; -.
DR PATRIC; fig|1193729.4.peg.62; -.
DR eggNOG; COG0008; Bacteria.
DR HOGENOM; CLU_015768_6_1_5; -.
DR OrthoDB; 9807503at2; -.
DR Proteomes; UP000010077; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004818; F:glutamate-tRNA ligase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0006424; P:glutamyl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 1.10.10.350; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR020751; aa-tRNA-synth_I_codon-bd_sub2.
DR InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR InterPro; IPR008925; aa_tRNA-synth_I_cd-bd_sf.
DR InterPro; IPR004527; Glu-tRNA-ligase_bac/mito.
DR InterPro; IPR000924; Glu/Gln-tRNA-synth.
DR InterPro; IPR020058; Glu/Gln-tRNA-synth_Ib_cat-dom.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00464; gltX_bact; 1.
DR PANTHER; PTHR43311; GLUTAMATE--TRNA LIGASE; 1.
DR PANTHER; PTHR43311:SF2; GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00749; tRNA-synt_1c; 1.
DR PRINTS; PR00987; TRNASYNTHGLU.
DR SUPFAM; SSF48163; An anticodon-binding domain of class I aminoacyl-tRNA synthetases; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000256|RuleBase:RU363037};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363037};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363037};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363037};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|RuleBase:RU363037}.
FT DOMAIN 3..305
FT /note="Glutamyl/glutaminyl-tRNA synthetase class Ib
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00749"
SQ SEQUENCE 447 AA; 50697 MW; C726F022DF74E0CD CRC64;
MAVFVRFAPS PTGLLHVGNT RQALINWLFA RAHGGDFMLR SDDTDAKRST IEFAEKIKRD
LNWLGLTWDV FSRQSDRLNR YAAEAERLKQ MGWLYPCYES AEELILKRRK QLSAGKPPIY
DRSALSLSYD EKAAKKAKGI LPYWRFKLNH ETVTWNDIIL GRSERDMALQ SDPIMIRADG
SPAYFMASVV DDIDFSILYI IRGEDHVTNS ATQIQIFRAL GAQPPMLGHT SLIVAADGSS
LSKRLGSISL EELRETHKLE AMAINSLLSG LGTNKIVPAT AMQQIVENFD ITRYSRANPH
FLLDNLIQIN AKILQETSYI DVADRLLNLE VSGGEKFWKA VRGNITRLYE VKEWWIVLNT
PITPMIAEED TEFCTTAADL LPFEELNKNT WDMWITAIKL KTARNGKSLF MTLRKALTAK
DSGPQLKDIL PMMSRQKIIA RLRGEIA
//
