ID K8E0J5_9FIRM Unreviewed; 221 AA.
AC K8E0J5;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Resolvase domain protein {ECO:0000313|EMBL:CCO09092.1};
GN ORFNames=DESHY_60264 {ECO:0000313|EMBL:CCO09092.1};
OS Desulforamulus hydrothermalis Lam5 = DSM 18033.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulforamulus.
OX NCBI_TaxID=1121428 {ECO:0000313|EMBL:CCO09092.1, ECO:0000313|Proteomes:UP000009315};
RN [1] {ECO:0000313|EMBL:CCO09092.1, ECO:0000313|Proteomes:UP000009315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lam5 / DSM 18033 {ECO:0000313|Proteomes:UP000009315};
RX PubMed=23405336; DOI=10.1128/genomeA.00114-12;
RA Amin O., Fardeau M.L., Valette O., Hirschler-Rea A., Barbe V., Medigue C.,
RA Vacherie B., Ollivier B., Bertin P.N., Dolla A.;
RT "Genome Sequence of the Sulfate-Reducing Bacterium Desulfotomaculum
RT hydrothermale Lam5(T).";
RL Genome Announc. 1:e00114-e00112(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCO09092.1}.
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DR EMBL; CAOS01000013; CCO09092.1; -; Genomic_DNA.
DR RefSeq; WP_008412889.1; NZ_CAOS01000013.1.
DR AlphaFoldDB; K8E0J5; -.
DR STRING; 1121428.DESHY_60264; -.
DR eggNOG; COG2452; Bacteria.
DR Proteomes; UP000009315; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd04761; HTH_MerR-SF; 1.
DR CDD; cd03769; SR_IS607_transposase_like; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 1.10.287.2170; -; 1.
DR Gene3D; 3.40.50.1390; Resolvase, N-terminal catalytic domain; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR041718; IS607_transposase-like.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR006118; Recombinase_CS.
DR InterPro; IPR006119; Resolv_N.
DR InterPro; IPR036162; Resolvase-like_N_sf.
DR InterPro; IPR048046; Transpos_IS607.
DR NCBIfam; NF033518; transpos_IS607; 1.
DR PANTHER; PTHR36172; -; 1.
DR PANTHER; PTHR36172:SF1; TRANSPOSASE IS605 ORFB C-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00376; MerR; 1.
DR Pfam; PF00239; Resolvase; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SMART; SM00857; Resolvase; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR SUPFAM; SSF53041; Resolvase-like; 1.
DR PROSITE; PS00552; HTH_MERR_1; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
DR PROSITE; PS00397; RECOMBINASES_1; 1.
DR PROSITE; PS51736; RECOMBINASES_3; 1.
PE 4: Predicted;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000009315}.
FT DOMAIN 3..51
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT DOMAIN 61..207
FT /note="Resolvase/invertase-type recombinase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51736"
FT ACT_SITE 69
FT /note="O-(5'-phospho-DNA)-serine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606118-50,
FT ECO:0000256|PROSITE-ProRule:PRU10137"
SQ SEQUENCE 221 AA; 25257 MW; A797D846F3FEA6A0 CRC64;
MELLTISKAA KKLGVHPNSL RNWEKQGLIK PVRLPGGQRR YSMDELNRLL QSGQLDAGQE
GVVLYARVST KKQADAGNLN RQLERLRQYV IESHYRVVAE VTDVASGLNQ KRRGLTNVLK
LAERGEYKKL IIEYPDRLAR FGYSYIERHL RYCGVEIVAI AEKEPEDAQS ELVRDLLAIV
TSFSARLYSA RGRKKVRQGF RELIAEASQN EKTEEQQEEA D
//
