ID K8EH24_9FIRM Unreviewed; 456 AA.
AC K8EH24;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN ORFNames=DESHY_160050 {ECO:0000313|EMBL:CCO07926.1};
OS Desulforamulus hydrothermalis Lam5 = DSM 18033.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulforamulus.
OX NCBI_TaxID=1121428 {ECO:0000313|EMBL:CCO07926.1, ECO:0000313|Proteomes:UP000009315};
RN [1] {ECO:0000313|EMBL:CCO07926.1, ECO:0000313|Proteomes:UP000009315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lam5 / DSM 18033 {ECO:0000313|Proteomes:UP000009315};
RX PubMed=23405336; DOI=10.1128/genomeA.00114-12;
RA Amin O., Fardeau M.L., Valette O., Hirschler-Rea A., Barbe V., Medigue C.,
RA Vacherie B., Ollivier B., Bertin P.N., Dolla A.;
RT "Genome Sequence of the Sulfate-Reducing Bacterium Desulfotomaculum
RT hydrothermale Lam5(T).";
RL Genome Announc. 1:e00114-e00112(2013).
CC -!- SIMILARITY: Belongs to the IS21/IS1162 putative ATP-binding protein
CC family. {ECO:0000256|ARBA:ARBA00008059}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCO07926.1}.
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DR EMBL; CAOS01000008; CCO07926.1; -; Genomic_DNA.
DR AlphaFoldDB; K8EH24; -.
DR STRING; 1121428.DESHY_160050; -.
DR eggNOG; COG1484; Bacteria.
DR eggNOG; COG4584; Bacteria.
DR Proteomes; UP000009315; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR047661; IstB.
DR InterPro; IPR002611; IstB_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR NCBIfam; NF038214; IS21_help_AAA; 1.
DR PANTHER; PTHR30050:SF4; ATP-BINDING PROTEIN RV3427C IN INSERTION SEQUENCE-RELATED; 1.
DR PANTHER; PTHR30050; CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA; 1.
DR Pfam; PF01695; IstB_IS21; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009315};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 1..80
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
SQ SEQUENCE 456 AA; 52290 MW; 1758A45D73A84CE6 CRC64;
MPTLLQRLGL FTKVCKVRRP ETKGKVERGV QYVKNNFLPG KRFVDLQDLN QQALHWCERI
NRRIHGTTGE RPIDRLREEN LSPIPSAERW EKYLHEPRQV SRDGFVSYDG VRYGVPWRYS
GREGTVREVN GWVEIWADGT CIARHQKVYR SRATVFCENQ YAGLTTAQGY AYPRPQARQI
SSQQVEVRSL DVYEQLTGGG SMIELEQARL RLEELGLQQA ALLLDAHLEA ASHGQPTYLS
FLNMLLDAEI AERQKRNMEV RTKLAHLPYR KTLEEFDFAF QPSIDERLIR ELATMTFVTR
HENVLFLGPP GVGKSHLAVA LAVEAISQGI SVYFVSLSQL IEDLRKAYTE NRLDKRLRIY
IRPKLLIIDE IGYLPFDSLA ANLFFQVVSA RYERGSILLT SNKSFGEWGE LMGDPILATA
ILDRLLHHSH IVNIRGNSYR LREKMRTGAY GSPSTT
//
