ID K8EIQ0_9FIRM Unreviewed; 391 AA.
AC K8EIQ0;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Putative AdoMet-dependent methyltransferase,UPF0064 family {ECO:0000313|EMBL:CCO08486.1};
GN Name=yccW {ECO:0000313|EMBL:CCO08486.1};
GN ORFNames=DESHY_40036 {ECO:0000313|EMBL:CCO08486.1};
OS Desulforamulus hydrothermalis Lam5 = DSM 18033.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulforamulus.
OX NCBI_TaxID=1121428 {ECO:0000313|EMBL:CCO08486.1, ECO:0000313|Proteomes:UP000009315};
RN [1] {ECO:0000313|EMBL:CCO08486.1, ECO:0000313|Proteomes:UP000009315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lam5 / DSM 18033 {ECO:0000313|Proteomes:UP000009315};
RX PubMed=23405336; DOI=10.1128/genomeA.00114-12;
RA Amin O., Fardeau M.L., Valette O., Hirschler-Rea A., Barbe V., Medigue C.,
RA Vacherie B., Ollivier B., Bertin P.N., Dolla A.;
RT "Genome Sequence of the Sulfate-Reducing Bacterium Desulfotomaculum
RT hydrothermale Lam5(T).";
RL Genome Announc. 1:e00114-e00112(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmI family.
CC {ECO:0000256|ARBA:ARBA00038091}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCO08486.1}.
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DR EMBL; CAOS01000011; CCO08486.1; -; Genomic_DNA.
DR RefSeq; WP_008411940.1; NZ_FQXF01000019.1.
DR AlphaFoldDB; K8EIQ0; -.
DR STRING; 1121428.DESHY_40036; -.
DR eggNOG; COG1092; Bacteria.
DR OrthoDB; 9805492at2; -.
DR Proteomes; UP000009315; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd21153; PUA_RlmI; 1.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42873:SF1; METHYLTRANS_SAM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42873; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CCO08486.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009315};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CCO08486.1}.
FT DOMAIN 2..87
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 391 AA; 43932 MW; 8AC18D01A8E3AF14 CRC64;
MAKAILHQGK QKRIINGHPW VYRGEIKEIK GPYAPGDIVD VYDCRDRFLG RGYINPASQI
TIRIMTRQPA EEIDEDFFRR RIQAAWQYRQ QVVRDTNACR VIFGEADFLP ALIVDKFADY
LVVQTLALGI DVHKATIFKV LQEVMQPAGI YERNDVAVRK LEGLPLITGF VGQPFDPKVV
IKENGIKFVV DLAGGQKTGY FLDQRENRMA LQGLVKGGRV LDCFCHTGTF AMYAAKYGAR
QVLGLDIAAP ALEVARANAQ LNGYGDLCSF KEGNSFDELR AMEKAGDKFD VVILDPPAFT
KSSQAVAGAV RGYKEINLRG MKLLPPGGYL ITCSCSYHMK EDLFLQVIQE AARDAGRQLR
LVELRRQAKD HPMLLAYPES HYLKCLVLQV W
//
