ID K8EXX2_9CHLO Unreviewed; 1006 AA.
AC K8EXX2;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=DNA mismatch repair protein msh-2 {ECO:0000313|EMBL:CCO14103.1};
GN ORFNames=Bathy01g00720 {ECO:0000313|EMBL:CCO14103.1};
OS Bathycoccus prasinos.
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Bathycoccaceae; Bathycoccus.
OX NCBI_TaxID=41875 {ECO:0000313|EMBL:CCO14103.1, ECO:0000313|Proteomes:UP000198341};
RN [1] {ECO:0000313|EMBL:CCO14103.1, ECO:0000313|Proteomes:UP000198341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC 1105 {ECO:0000313|EMBL:CCO14103.1,
RC ECO:0000313|Proteomes:UP000198341};
RA Genoscope - CEA;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
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DR EMBL; FO082278; CCO14103.1; -; Genomic_DNA.
DR RefSeq; XP_007515224.1; XM_007515162.1.
DR AlphaFoldDB; K8EXX2; -.
DR STRING; 41875.K8EXX2; -.
DR GeneID; 19017808; -.
DR KEGG; bpg:Bathy01g00720; -.
DR eggNOG; KOG0219; Eukaryota.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000198341; Chromosome_1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF35; DNA MISMATCH REPAIR PROTEIN MSH2; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000198341}.
FT DOMAIN 808..824
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 915..944
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 924..941
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1006 AA; 112518 MW; B46A01A73BAD7840 CRC64;
MGTTSFAPRE QDAILPDASG FVRFYETTFT NVFSKKNDDD DKKESEEEEK QHHSLRFFNR
SKHEGWSVCA DDAFYVARRF YKTTTVVKYL KDAGGNSQFI LPSVNINQNL FETICRDVLL
HTRERTVEVY ESEPNSRGDF KLTKRGSPGN VLDFEDILFD GSKENDLNNN NNKNNANADT
DSLPIVCAVK CVLKQEQRRI GLAFFEYSTR TLRALEFSDE ERLGQLESIL AQINAREVIV
PNEIDKASGG AMTADAKRIA DVIDRCDAMR TAKANSEYFR TDDVEDDLKR LLKSGDNVQA
HRNVLDLPLA VQCLHAVMKF ADIGNDAQNH GRCELELFDS GAHVRLDAAA LKALNVLPSS
GGGGDRSFGE TAGKGSGGGF SLYNLLNRCT SPMGKRVLYR WLKQPLVSVE KISERHDVVE
TFSEESALRD SLRNAHLKSL PDVERLARKL EKKKTTLMDL CKLYQASSAI PHAIDCLERI
PFSDETRKAL FISKYISPLK ECVEEEKLGK FEALIEHAVD LNKIPDEYVI SAEFDDTLAL
LEQQKISTEE EINVVWQEAA EDLTMERDKQ LKLEKNNQHG YFFRLTKKDE TAARSKLSKS
AQFQILEAKK DGSKFTNKKL RALSQKRLEI DRTYEAKQKH LVQRVLDVAV SFVDIFLKAS
SVMAELDVLC AFAEVAQNAP TPYVRPQMTN ADEKELVLLD SRHPLVEVQE SCGEFVQNSC
KMIKGESWFQ IITGPNMGGK STFIRQVGVN VLLAQVGSFV PCSKAIIPVR DAIFCRIGAG
DFQLRGVSTF MAEMLESASI LRSATEKSLV IIDELGRGTS TYDGFGLAWG IAEHLANEVK
APCLFATHFH ELTELKGETG VKNFHVSAKI DVASKKIAML YALEEGACDQ SFGIHCAEFS
GFPAEALEDA RKCAEELENG GNSAGNDDKE NTTNSNKSDG IDDADATYGR KRAMQFLNDF
KNIPLPQLAP QDVIERVKKL KTELERDASK SKWLQNVFEE INKSAA
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