ID   K8GGA2_9CYAN            Unreviewed;       483 AA.
AC   K8GGA2;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Multidrug resistance efflux pump {ECO:0000313|EMBL:EKQ67580.1};
GN   ORFNames=OsccyDRAFT_3861 {ECO:0000313|EMBL:EKQ67580.1};
OS   Leptolyngbyaceae cyanobacterium JSC-12.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Leptolyngbyales; Leptolyngbyaceae.
OX   NCBI_TaxID=864702 {ECO:0000313|EMBL:EKQ67580.1, ECO:0000313|Proteomes:UP000001332};
RN   [1] {ECO:0000313|EMBL:EKQ67580.1, ECO:0000313|Proteomes:UP000001332}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JSC-12 {ECO:0000313|EMBL:EKQ67580.1,
RC   ECO:0000313|Proteomes:UP000001332};
RG   DOE Joint Genome Institute;
RA   Brown I., Huntemann M., Wei C.-L., Han J., Detter J.C., Han C., Tapia R.,
RA   Chen A., Kyrpides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA   Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L.,
RA   Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RT   "Improved high quality draft of Oscillatoriales sp. JSC-12.";
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKQ67580.1}.
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DR   EMBL; AJUB01000015; EKQ67580.1; -; Genomic_DNA.
DR   AlphaFoldDB; K8GGA2; -.
DR   STRING; 864702.OsccyDRAFT_3861; -.
DR   eggNOG; COG0845; Bacteria.
DR   HOGENOM; CLU_023976_0_0_3; -.
DR   OrthoDB; 553569at2; -.
DR   Proteomes; UP000001332; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR   PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR   PANTHER; PTHR30386:SF26; TRANSPORT PROTEIN COMB; 1.
DR   Pfam; PF13533; Biotin_lipoyl_2; 1.
DR   Pfam; PF13437; HlyD_3; 1.
DR   PRINTS; PR01490; RTXTOXIND.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001332};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          58..100
FT                   /note="Membrane fusion protein biotin-lipoyl like"
FT                   /evidence="ECO:0000259|Pfam:PF13533"
FT   COILED          180..214
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          239..273
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          307..334
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   483 AA;  53920 MW;  36FC899FD516378B CRC64;
     MSTHFDQPVI LRRSPKWSRA VVWGIVGVTT FTVLWAYFAK LEEAVSATGQ LEPQGTVREV
     RVPLNGVVRV VHVKDGDRVN QGDLLITLDQ KTAEAQLKSL TKIRDALKAE TLFYRQEMGN
     LVPDAASETP EFKIPAETLA LTKSRRALIA ETALYRAQLS GSTKGMQLSP EQALRLQSSL
     EEVRTRQRTA QLEAEQLEKQ LAQNRVQLST AREILQINEG IFKDLTQVAQ EGGLPRIQYL
     RQEQEVKSSQ ARVQQLQEEQ GRLRLAIAQA QQKLQNTIAL SNQDLLTKIS ENEKRIAQID
     GELNKAIVEN EKKIAEIDSQ LKQAEQTLQY QEVRAPVEGT IFDLKASGPG YVATTSEPVL
     KVVPKDALKV ELFVPNKDIG FIKTGLPVDV RVDSFPFSEF GDLKGVVESI GSDALPPTQV
     RQFYSFPVTV RLDNVDGLKD NGRDLRLQSG MSVSANIKIR QRSVMSIFVD GFTQKVDSFK
     SVR
//