ID   K8GI26_9CYAN            Unreviewed;       459 AA.
AC   K8GI26;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE {ECO:0000256|ARBA:ARBA00013280};
GN   ORFNames=OsccyDRAFT_4971 {ECO:0000313|EMBL:EKQ67146.1};
OS   Leptolyngbyaceae cyanobacterium JSC-12.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Leptolyngbyales; Leptolyngbyaceae.
OX   NCBI_TaxID=864702 {ECO:0000313|EMBL:EKQ67146.1, ECO:0000313|Proteomes:UP000001332};
RN   [1] {ECO:0000313|EMBL:EKQ67146.1, ECO:0000313|Proteomes:UP000001332}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JSC-12 {ECO:0000313|EMBL:EKQ67146.1,
RC   ECO:0000313|Proteomes:UP000001332};
RG   DOE Joint Genome Institute;
RA   Brown I., Huntemann M., Wei C.-L., Han J., Detter J.C., Han C., Tapia R.,
RA   Chen A., Kyrpides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA   Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L.,
RA   Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RT   "Improved high quality draft of Oscillatoriales sp. JSC-12.";
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC       prosthetic group of nitrogenase (FeMo cofactor).
CC       {ECO:0000256|ARBA:ARBA00003171}.
CC   -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00005155}.
CC   -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family.
CC       {ECO:0000256|ARBA:ARBA00011002, ECO:0000256|RuleBase:RU004021}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKQ67146.1}.
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DR   EMBL; AJUB01000019; EKQ67146.1; -; Genomic_DNA.
DR   AlphaFoldDB; K8GI26; -.
DR   STRING; 864702.OsccyDRAFT_4971; -.
DR   PATRIC; fig|864702.5.peg.5360; -.
DR   eggNOG; COG2710; Bacteria.
DR   HOGENOM; CLU_025876_1_1_3; -.
DR   OrthoDB; 9767044at2; -.
DR   UniPathway; UPA00782; -.
DR   Proteomes; UP000001332; Chromosome.
DR   GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   CDD; cd01968; Nitrogenase_NifE_I; 1.
DR   Gene3D; 3.40.50.12380; Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal; 1.
DR   Gene3D; 3.40.50.1980; Nitrogenase molybdenum iron protein domain; 1.
DR   InterPro; IPR000510; Nase/OxRdtase_comp1.
DR   InterPro; IPR000318; Nase_comp1_CS.
DR   InterPro; IPR005973; NifE.
DR   NCBIfam; TIGR01283; nifE; 1.
DR   PANTHER; PTHR42956; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR   PANTHER; PTHR42956:SF1; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR   Pfam; PF00148; Oxidored_nitro; 1.
DR   SUPFAM; SSF53807; Helical backbone' metal receptor; 1.
DR   PROSITE; PS00699; NITROGENASE_1_1; 1.
DR   PROSITE; PS00090; NITROGENASE_1_2; 1.
PE   3: Inferred from homology;
KW   Nitrogen fixation {ECO:0000256|ARBA:ARBA00023231,
KW   ECO:0000256|RuleBase:RU004021};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001332}.
FT   DOMAIN          45..440
FT                   /note="Nitrogenase/oxidoreductase component 1"
FT                   /evidence="ECO:0000259|Pfam:PF00148"
SQ   SEQUENCE   459 AA;  50175 MW;  C9249DCDD9EA6BF1 CRC64;
     MKLTQGKINE LLSESACEHN HKKEGKGKNK SCTQVAQPGA AQGGCAFDGA MIALVPITDA
     AHLVHGPIAC AGNSWGSRGS LSSGSMLYKM GFTTDLTENE VIFGGEKKLY KAILEVKERY
     NPSAVFVYST CVTALIGDDL DAVCQKAAEK TGVPVIPVNS PGFIGSKNLG NRVGGESLLE
     YVVGTREPAY TTPYDINLIG EYNIAGELWG VLPLFEKLGI RVLAQITGDG RYEDIACSHR
     AKLNVMICSK ALINMARKME EKYGIPYIEE SFYGIADMNR CLRNIAAKIG DADLQQRVEQ
     LITEETLKLD NALAPYRERL KGKRVVLYTG GVKSWSIISA AKDLGMEVCA TSTKKSTEED
     KARIKELLGK DGIMLEKGNA QELLKVIAQT KADMLIAGGR NQYTALKAKI PFLDINQERH
     HPYAGYVGMV EMARELEEAL YSPVWAQVRK PAPWDTEVI
//