ID K8WN88_9GAMM Unreviewed; 693 AA.
AC K8WN88;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=ComEC family competence protein {ECO:0000313|EMBL:EKT62088.1};
GN ORFNames=OOA_09356 {ECO:0000313|EMBL:EKT62088.1};
OS Providencia burhodogranariea DSM 19968.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Providencia.
OX NCBI_TaxID=1141662 {ECO:0000313|EMBL:EKT62088.1, ECO:0000313|Proteomes:UP000009336};
RN [1] {ECO:0000313|EMBL:EKT62088.1, ECO:0000313|Proteomes:UP000009336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19968 {ECO:0000313|EMBL:EKT62088.1,
RC ECO:0000313|Proteomes:UP000009336};
RX PubMed=23145767; DOI=10.1186/1471-2164-13-612;
RA Galac M.R., Lazzaro B.P.;
RT "Comparative genomics of bacteria in the genus Providencia isolated from
RT wild Drosophila melanogaster.";
RL BMC Genomics 13:612-612(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKT62088.1}.
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DR EMBL; AKKL01000022; EKT62088.1; -; Genomic_DNA.
DR AlphaFoldDB; K8WN88; -.
DR STRING; 1141662.OOA_09356; -.
DR PATRIC; fig|1141662.3.peg.1897; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR HOGENOM; CLU_010363_3_0_6; -.
DR Proteomes; UP000009336; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 200..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 447..628
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 693 AA; 79370 MW; 7472E202072330D9 CRC64;
MIGKINFLSK SKQQLEVTII SIPLLIKQNM RVKVRIDKID EVIVFPPLYA IWQLRYQHEN
SICAGQVWHI NGALKPLHAS LNEGGFDQLR FSLSQRIIGT FKNTQSTVIN SKCSLRQEII
NHYIKKINLL DNSGVIYALM FGERGLLTVD SSALLKNTGL SHLIAISGLH IGMSYLFGYC
FARLCLYLLP TYFIYPKTPI LFGLIFAFLY AWVSGFAIPA TRALISLVLW IYIKQQSCHF
FSWQWAVWSI GLIIVADPLA ILSDSFWLSS FAVLAILYWF ALYPIPSFSY HPKIVSQLIP
LFHLQVGLLV LLAPIQIILF QGINFMSFWA NLWLVPIVSW LVVPAIFLLF LIPVSEVQNI
IFQCIDKILS IGIAPLPYLS DFWFGLQTTS LWFFVCCWLI SGFIALGWHK TYIGLLGCFI
ALYLNSDSFA NKPHNEGWKL TTLDVGHGLA VVIEQNGLAY LYDTGNRWPE GSSAQRQIIP
YLKHKSITPI GIILSHNHLD HTGGVDLLIT QYPWINLRSS FGSNQHLPCH KGQRWKWGIL
NFEVLWPEQF SKISHNDDSC VIQISDGYHK VLLTGDIEEH SEKAITAMYK QKLRSDIIFA
PHHGSRTSST SLFIRTVAPT MVLVSSARYS AWKIPSDKVH LRYRENNIKW FNTAESGQVT
IWFKKKNLTL TRFRLEIQPR WYHLWFGDPL FPE
//
