ID K8WT36_9GAMM Unreviewed; 105 AA.
AC K8WT36;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Lipopolysaccharide assembly protein A {ECO:0000256|HAMAP-Rule:MF_01948};
GN Name=lapA {ECO:0000256|HAMAP-Rule:MF_01948};
GN ORFNames=OOA_05172 {ECO:0000313|EMBL:EKT63738.1};
OS Providencia burhodogranariea DSM 19968.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Providencia.
OX NCBI_TaxID=1141662 {ECO:0000313|EMBL:EKT63738.1, ECO:0000313|Proteomes:UP000009336};
RN [1] {ECO:0000313|EMBL:EKT63738.1, ECO:0000313|Proteomes:UP000009336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19968 {ECO:0000313|EMBL:EKT63738.1,
RC ECO:0000313|Proteomes:UP000009336};
RX PubMed=23145767; DOI=10.1186/1471-2164-13-612;
RA Galac M.R., Lazzaro B.P.;
RT "Comparative genomics of bacteria in the genus Providencia isolated from
RT wild Drosophila melanogaster.";
RL BMC Genomics 13:612-612(2012).
CC -!- FUNCTION: Involved in the assembly of lipopolysaccharide (LPS).
CC {ECO:0000256|HAMAP-Rule:MF_01948}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_01948}; Single-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_01948}.
CC -!- SIMILARITY: Belongs to the LapA family. {ECO:0000256|HAMAP-
CC Rule:MF_01948}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01948}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKT63738.1}.
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DR EMBL; AKKL01000014; EKT63738.1; -; Genomic_DNA.
DR RefSeq; WP_008911069.1; NZ_KB233222.1.
DR AlphaFoldDB; K8WT36; -.
DR STRING; 1141662.OOA_05172; -.
DR PATRIC; fig|1141662.3.peg.1052; -.
DR eggNOG; COG3771; Bacteria.
DR HOGENOM; CLU_160072_0_0_6; -.
DR OrthoDB; 7064015at2; -.
DR Proteomes; UP000009336; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008653; P:lipopolysaccharide metabolic process; IEA:InterPro.
DR HAMAP; MF_01948; LPS_assembly_LapA; 1.
DR InterPro; IPR032906; LapA.
DR InterPro; IPR010445; LapA_dom.
DR Pfam; PF06305; LapA_dom; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01948};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01948}; Coiled coil {ECO:0000256|HAMAP-Rule:MF_01948};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01948};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01948};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01948}.
FT TRANSMEM 45..69
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01948"
FT DOMAIN 24..85
FT /note="Lipopolysaccharide assembly protein A"
FT /evidence="ECO:0000259|Pfam:PF06305"
FT COILED 64..91
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01948"
SQ SEQUENCE 105 AA; 11562 MW; AA3001976BF69CE9 CRC64;
MKYFLILLLA VVIFIISITL GSSNNQVITF NYLIAQGDFS VSSLLASLFG VGFVLGWLVA
GVFYLRAMIS LKNARRKIKR LESQLSASDK TIPESSELVT AKSKE
//
