ID K9ANP6_9STAP Unreviewed; 437 AA.
AC K9ANP6;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Putative transport protein {ECO:0000313|EMBL:EKU49003.1};
GN ORFNames=C273_04340 {ECO:0000313|EMBL:EKU49003.1};
OS Staphylococcus massiliensis S46.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=1229783 {ECO:0000313|EMBL:EKU49003.1, ECO:0000313|Proteomes:UP000009885};
RN [1] {ECO:0000313|EMBL:EKU49003.1, ECO:0000313|Proteomes:UP000009885}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S46 {ECO:0000313|EMBL:EKU49003.1,
RC ECO:0000313|Proteomes:UP000009885};
RX PubMed=23929469;
RA Srivastav R., Singh A., Jangir P.K., Kumari C., Muduli S., Sharma R.;
RT "Genome Sequence of Staphylococcus massiliensis Strain S46, Isolated from
RT the Surface of Healthy Human Skin.";
RL Genome Announc. 1:e00553-13(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter
CC family. {ECO:0000256|ARBA:ARBA00038435}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKU49003.1}.
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DR EMBL; AMSQ01000005; EKU49003.1; -; Genomic_DNA.
DR RefSeq; WP_009382894.1; NZ_AMSQ01000005.1.
DR AlphaFoldDB; K9ANP6; -.
DR STRING; 1229783.C273_04340; -.
DR PATRIC; fig|1229783.3.peg.875; -.
DR eggNOG; COG1757; Bacteria.
DR OrthoDB; 9790605at2; -.
DR Proteomes; UP000009885; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR PANTHER; PTHR33451; MALATE-2H(+)/NA(+)-LACTATE ANTIPORTER; 1.
DR PANTHER; PTHR33451:SF5; NA+_H+ ANTIPORTER-RELATED; 1.
DR Pfam; PF03553; Na_H_antiporter; 2.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009885};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..208
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
FT DOMAIN 236..422
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 437 AA; 46352 MW; 7C0AA7C2F53CC80A CRC64;
MTKEKGNVWG LLPLLIFVTL FIGVGIITGN FSTMPLNISI MIAVVIALFM NHKTSFSKKV
DVFTKGAGHS NIILMVFIFL LAGAFSKVTE EMGGVESTVN LGLSLIPTNL LLVGLFLICM
FISISMGTSV GTVAAIAPVG FGISQATDLS SALVMATVVG GAMFGDNLSM ISDTTIAAVR
TQKTQMKDKF KVNFRIVLPG AILTMVLLWI LTHGITLDQS KSYDFNLVKV IPYLLVLILA
LIGVNVVIVL LSGTLLSGII GFIDGSFDWK GFLKAASEGV IGMEDTAIIA LLIGGLISII
EFNGGIRWLL EFVNAKVKSR RGAELGIAGL VSVADISTAN NTISILMAGP LAKRIADKYD
IDPRKSASIL DIFGSCFQGF LPYSPQVIAA AGVASISPVM LIPYSFYPFI LGISGVVAII
LGLPVLKSKR KAAHNEN
//
