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Database: UniProt
Entry: K9CFE9_9FIRM
LinkDB: K9CFE9_9FIRM
Original site: K9CFE9_9FIRM 
ID   K9CFE9_9FIRM            Unreviewed;       210 AA.
AC   K9CFE9;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   RecName: Full=DUF421 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF9161_01423 {ECO:0000313|EMBL:EKU70874.1};
OS   Selenomonas sp. F0473.
OC   Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC   Selenomonas.
OX   NCBI_TaxID=999423 {ECO:0000313|EMBL:EKU70874.1, ECO:0000313|Proteomes:UP000009883};
RN   [1] {ECO:0000313|EMBL:EKU70874.1, ECO:0000313|Proteomes:UP000009883}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0473 {ECO:0000313|EMBL:EKU70874.1,
RC   ECO:0000313|Proteomes:UP000009883};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Blanton J.M., Baranova O.V.,
RA   Mathney J., Dewhirst F.E., Izard J., Tanner A.C., Walker B., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Selenomonas sp. Oral taxon 133 strain F0473.";
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the UPF0702 family.
CC       {ECO:0000256|ARBA:ARBA00006448}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKU70874.1}.
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DR   EMBL; AGZT01000007; EKU70874.1; -; Genomic_DNA.
DR   RefSeq; WP_009729021.1; NZ_JH992902.1.
DR   AlphaFoldDB; K9CFE9; -.
DR   STRING; 999423.HMPREF9161_01423; -.
DR   PATRIC; fig|999423.3.peg.1492; -.
DR   eggNOG; COG2323; Bacteria.
DR   HOGENOM; CLU_077149_4_0_9; -.
DR   OrthoDB; 9778331at2; -.
DR   Proteomes; UP000009883; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.240.20; bsu07140 like domains; 2.
DR   InterPro; IPR007353; DUF421.
DR   InterPro; IPR023090; UPF0702_alpha/beta_dom_sf.
DR   InterPro; IPR048454; YetF_N.
DR   PANTHER; PTHR34582; UPF0702 TRANSMEMBRANE PROTEIN YCAP; 1.
DR   PANTHER; PTHR34582:SF6; UPF0702 TRANSMEMBRANE PROTEIN YCAP; 1.
DR   Pfam; PF04239; DUF421; 1.
DR   Pfam; PF20730; YetF_N; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009883};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          5..79
FT                   /note="YetF-like N-terminal transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF20730"
FT   DOMAIN          83..198
FT                   /note="YetF C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04239"
SQ   SEQUENCE   210 AA;  23414 MW;  B4FE53BD63FB7D0C CRC64;
     MIVYSLVLVK LALGLLCLIL QINLLGKGNL APSSATDQVQ NYVLGGIIGG VIYNNDISVL
     EFVLELIAWT LLVLVLKYVK STSSAVKGFV DGRPAVLIER GVLKVEECMR HGMLAHDIHL
     KLRMAGVYFV KDVKRAVLEP NGQLTVIQYG EQNARYPLIL DGQIDDDALE LVDKDRVWLK
     GALREAGYEL KDIYIGEYKE GELVFYLYES
//
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