ID K9D4P7_9BURK Unreviewed; 457 AA.
AC K9D4P7;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Histidine kinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF9710_05076 {ECO:0000313|EMBL:EKU79594.1};
OS Massilia timonae CCUG 45783.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Telluria group; Massilia.
OX NCBI_TaxID=883126 {ECO:0000313|EMBL:EKU79594.1, ECO:0000313|Proteomes:UP000009874};
RN [1] {ECO:0000313|EMBL:EKU79594.1, ECO:0000313|Proteomes:UP000009874}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 45783 {ECO:0000313|EMBL:EKU79594.1,
RC ECO:0000313|Proteomes:UP000009874};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Huys G., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Massilia timonae CCUG 45783.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKU79594.1}.
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DR EMBL; AGZI01000065; EKU79594.1; -; Genomic_DNA.
DR RefSeq; WP_005671301.1; NZ_JH992927.1.
DR AlphaFoldDB; K9D4P7; -.
DR STRING; 47229.LO55_4884; -.
DR GeneID; 84814386; -.
DR PATRIC; fig|883126.3.peg.5132; -.
DR eggNOG; COG4564; Bacteria.
DR HOGENOM; CLU_000445_20_6_4; -.
DR OrthoDB; 9797605at2; -.
DR Proteomes; UP000009874; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR033480; sCache_2.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR InterPro; IPR017171; Sig_transdc_His_kinase_MctS.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF37; SIGNAL TRANSDUCTION HISTIDINE-PROTEIN KINASE_PHOSPHATASE UHPB; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF17200; sCache_2; 1.
DR PIRSF; PIRSF037314; STHK_MctS; 1.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009874};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..132
FT /note="Single Cache"
FT /evidence="ECO:0000259|SMART:SM01049"
FT DOMAIN 357..452
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
SQ SEQUENCE 457 AA; 49790 MW; D2DB01D99F3805DC CRC64;
MRLRQKVIVL AVVPLVVALC AIALYVRQQG VTLAAEQRAT IQHAYLASKE AELRHYVELA
TRSIAHLTRT GDSGPATQRE AIRILSSLSY GEDGYFFVYD TRGNNLMHPR QPELVGTDMW
DWRDSTGAPT IQRLIALAGE GGGFLRYTWA KPSSNRPAPK LGYVVPVAHW NWVMGTGIYL
DDVESALALV DAQQSRNIEE TLLWMAVLAT VAAVGVAGGG LALNISEGRV ADAKLKALAQ
RVVESQEEER ARLSRDLHDG ISQALVSVKL QLEAGIIRID GDEARREQGR AGLERTVEQV
KTLLGEVRRI SHDLRPTLLD DMGLAPALDH LASEFGEHAG APVRFRAAGA VDALPEIVGT
VLFRIAQEAL TNVERHAQAR HIDMVLERVG DLVSLSIADD GVGFDTDGVA VHPKRGIGLR
NMMERMEAIG GRFEIVSSST GTRVVASIDL KEQGSDW
//
