ID K9E897_9LACT Unreviewed; 373 AA.
AC K9E897;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Tyr recombinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF9698_01142 {ECO:0000313|EMBL:EKU93394.1};
OS Alloiococcus otitis ATCC 51267.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Alloiococcus.
OX NCBI_TaxID=883081 {ECO:0000313|EMBL:EKU93394.1, ECO:0000313|Proteomes:UP000009875};
RN [1] {ECO:0000313|EMBL:EKU93394.1, ECO:0000313|Proteomes:UP000009875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51267 {ECO:0000313|EMBL:EKU93394.1,
RC ECO:0000313|Proteomes:UP000009875};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Huys G., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Alloiococcus otitis ATCC 51267.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKU93394.1}.
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DR EMBL; AGXA01000021; EKU93394.1; -; Genomic_DNA.
DR RefSeq; WP_003778269.1; NZ_JH992959.1.
DR AlphaFoldDB; K9E897; -.
DR STRING; 883081.HMPREF9698_01142; -.
DR eggNOG; COG0582; Bacteria.
DR HOGENOM; CLU_027562_17_6_9; -.
DR OrthoDB; 9803188at2; -.
DR Proteomes; UP000009875; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd01189; INT_ICEBs1_C_like; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR028259; AP2-like_int_N.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF14657; Arm-DNA-bind_4; 1.
DR Pfam; PF14659; Phage_int_SAM_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000009875};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 60..141
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 165..358
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 373 AA; 43395 MW; 679955C0D1BABF36 CRC64;
MAFLKKVKSG WKYRISYKDP MTQELKQKSK SGFATKKEAQ LHAAKTKEKL EQGLNFSKDI
SFIDYFEEWY KTYKKDKFSP SYNKDVETAI EQARDYFGQM KLKNITKHVY QKFLNDFGQG
RTTSTVKKKH VFIGECLTDA FHEGLIPKDP TYKVTITGTK DRYEEADMYL NYNEAIKLSE
QLKQNLKPTY TSRYMILLAL ATGLRFSEIV GLAWDDIDFE GHTLSVNRMF DYRTSQKFQK
PKSEKSKRTI ALDKATVAWL KRYKLQVQKD YPQYIFMDKF GQHVSNSGVN KALKKACSKA
GVKEITFHKL RHTHCSILLY KGINIKYISK RLGHSSTQIT YEVYGHILDE LDQQEAQRVD
DIMAEITSAG VHN
//
