ID   K9E9K0_9BACE            Unreviewed;       334 AA.
AC   K9E9K0;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Thiamine pyrophosphate enzyme TPP-binding domain-containing protein {ECO:0000259|Pfam:PF02775};
GN   ORFNames=HMPREF9447_05071 {ECO:0000313|EMBL:EKU87612.1};
OS   Bacteroides oleiciplenus YIT 12058.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=742727 {ECO:0000313|EMBL:EKU87612.1, ECO:0000313|Proteomes:UP000009872};
RN   [1] {ECO:0000313|EMBL:EKU87612.1, ECO:0000313|Proteomes:UP000009872}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIT 12058 {ECO:0000313|EMBL:EKU87612.1,
RC   ECO:0000313|Proteomes:UP000009872};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Morotomi M., Walker B.,
RA   Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A.,
RA   Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J.,
RA   McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Bacteroides oleiciplenus YIT 12058.";
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKU87612.1}.
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DR   EMBL; ADLF01000024; EKU87612.1; -; Genomic_DNA.
DR   RefSeq; WP_009132449.1; NZ_JH992946.1.
DR   AlphaFoldDB; K9E9K0; -.
DR   STRING; 742727.HMPREF9447_05071; -.
DR   PATRIC; fig|742727.4.peg.5181; -.
DR   eggNOG; COG1013; Bacteria.
DR   HOGENOM; CLU_048564_1_0_10; -.
DR   OrthoDB; 9775140at2; -.
DR   Proteomes; UP000009872; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   CDD; cd03375; TPP_OGFOR; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR   PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR   PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          49..196
FT                   /note="Thiamine pyrophosphate enzyme TPP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02775"
SQ   SEQUENCE   334 AA;  36764 MW;  128DA2F461B33C53 CRC64;
     MSEYTAKDFK KGQPRWCPGC GDHFFLNSLH KALAEIGVRP WETAVISGIG CSSRLPYYMN
     TYAMQTIHGR AAAISTGCKV ANPKLSVWQV SGDGDGLAIG GNHFIHAIRR NIDINILLLN
     NRIYGLTKGQ YSPTSPRGFV SKSSPYGTVE DPFHPAELCF GARGRFFARC VATDGPGTGE
     VLKAAAGHKG TAVCEILQHC VIFNDGTYDS VYNKEGRAKN AIYLEHGQPM LFGENKEFGL
     MQEGFGLKVV KLGENGITEK DILVHDAHCM DNTLQLKLAL MEGPDFPVAL GVIRDVEAPT
     YDDAVMEQIE EVSAKKKYHN FKELLMTNDI WEVK
//