ID K9EYE3_9ACTO Unreviewed; 520 AA.
AC K9EYE3;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=AspT/YidE/YbjL antiporter duplication domain-containing protein {ECO:0000313|EMBL:EKU95997.1};
GN ORFNames=HMPREF9233_00085 {ECO:0000313|EMBL:EKU95997.1};
OS Actinobaculum massiliense ACS-171-V-Col2.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinobaculum.
OX NCBI_TaxID=883066 {ECO:0000313|EMBL:EKU95997.1, ECO:0000313|Proteomes:UP000009888};
RN [1] {ECO:0000313|EMBL:EKU95997.1, ECO:0000313|Proteomes:UP000009888}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-171-V-Col2 {ECO:0000313|Proteomes:UP000009888};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Saerens B., Vaneechoutte M.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Larimer J., McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Actinobaculum massiliae ACS-171-V-COL2.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC {ECO:0000256|ARBA:ARBA00009854}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKU95997.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGWL01000001; EKU95997.1; -; Genomic_DNA.
DR RefSeq; WP_007000303.1; NZ_JH992955.1.
DR AlphaFoldDB; K9EYE3; -.
DR STRING; 202789.GCA_001457435_00155; -.
DR PATRIC; fig|883066.3.peg.88; -.
DR eggNOG; COG2985; Bacteria.
DR HOGENOM; CLU_035023_3_0_11; -.
DR Proteomes; UP000009888; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR006512; YidE_YbjL.
DR NCBIfam; TIGR01625; YidE_YbjL_dupl; 2.
DR PANTHER; PTHR30445:SF3; TRANSPORT PROTEIN YIDE-RELATED; 1.
DR PANTHER; PTHR30445; UNCHARACTERIZED; 1.
DR Pfam; PF06826; Asp-Al_Ex; 2.
DR Pfam; PF02080; TrkA_C; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009888};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 172..253
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 255..338
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 520 AA; 54996 MW; A6153E5949220638 CRC64;
MLDVLSANSV LLTFLVITLG ALVGAIPIGP VKFGAAGALF VGLAFGAFTH VNPAVLSVFQ
DLGLGMFVYL IGLEAGETFF KEIKQQFALM LVAMVAVTLG AISAVTSGEL IGLEREISVG
AFAGSLTSTP SLALATEQAG NDLPSVGYSI GYPVGIAVAI VLIALTINRE WKARNDLVNA
DDAILRNIRV RVKHATSGME LEEKFGSFIR IATIRRQSHT LIARPNQDLQ EGDVVSLFVT
KSAENEIIKF MGTRVPRNPF ADPRISMRRV QLSNRDLAGR QVADIPLFKN FQSRITKIRR
GDSEFLVNPD TYLELGDTVE LVVMSRNAAA VSAYFGDSIQ TSSELDTVAT FGGLALGFAV
GLITVPLPGG ASFKLGAAAG PIIVGMILGA IHRTGAIPWQ IPRSANYTLR QLGLLVFLAS
VGLASGDAFA STAFSMTGLK TIIVCVIVGL FGCGSFIIIS WLMGRSPARA NGGVAGVLGQ
PAVLSYATSK TSDPRIMSGY ATTFAIALIY KIVIVPFMFV
//
