ID K9F8J0_PEND2 Unreviewed; 1119 AA.
AC K9F8J0;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Voltage-gated chloride channel, putative {ECO:0000313|EMBL:EKV05419.1};
GN ORFNames=PDIG_83980 {ECO:0000313|EMBL:EKV05419.1};
OS Penicillium digitatum (strain PHI26 / CECT 20796) (Green mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1170229 {ECO:0000313|EMBL:EKV05419.1, ECO:0000313|Proteomes:UP000009882};
RN [1] {ECO:0000313|Proteomes:UP000009882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI26 / CECT 20796 {ECO:0000313|Proteomes:UP000009882};
RX PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT postharvest pathogen of citrus.";
RL BMC Genomics 13:646-646(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKV05419.1}.
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DR EMBL; AKCT01000307; EKV05419.1; -; Genomic_DNA.
DR AlphaFoldDB; K9F8J0; -.
DR STRING; 1170229.K9F8J0; -.
DR eggNOG; KOG0475; Eukaryota.
DR HOGENOM; CLU_003181_1_0_1; -.
DR InParanoid; K9F8J0; -.
DR OMA; CLDWTPW; -.
DR OrthoDB; 150430at2759; -.
DR Proteomes; UP000009882; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd04591; CBS_pair_voltage-gated_CLC_euk_bac; 1.
DR CDD; cd03684; ClC_3_like; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 3.10.580.20; -; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR006569; CID_dom.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR InterPro; IPR024637; Ctk3_C.
DR InterPro; IPR024638; Ctk3_N.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR45711; CHLORIDE CHANNEL PROTEIN; 1.
DR PANTHER; PTHR45711:SF6; CHLORIDE CHANNEL PROTEIN; 1.
DR Pfam; PF12243; CTK3; 1.
DR Pfam; PF12350; CTK3_C; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51391; CID; 1.
PE 4: Predicted;
KW Chloride {ECO:0000256|ARBA:ARBA00023214};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009882};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 163..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 516..537
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..565
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..603
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 609..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 876..1011
FT /note="CID"
FT /evidence="ECO:0000259|PROSITE:PS51391"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 65..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1009..1036
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1119 AA; 124502 MW; 1E50F98F6FD81DBF CRC64;
MMPISCQGSG GEGQSGTHLR ADQDILQPQE VNWEAEGLHE PISFKRKQKQ RSRFSLSSLL
SSRASGSDTG FGSPAPQVGQ NGDASPLDPY VPIGFNSGAE ASKDGAPLDW YVEGPGRRVG
YDDFTAIDWI YEYTKERQRK RLLYSSGQGL LGHARRLLDA SNVWLVLIAT GIAVGIIAAS
IDIATDWLGD LKSGYCKNGS GGGKFYLNKS FCCWGLDDHS KCLDWTPWGN ALGANSSGGI
FTIGYAFYIV SSVFFAACAC FLVRNYAAYA RHSGIPEIKT ILGGTVIRHF MGPWTLAIKS
LGLCLSVASG LWLGKEGPLV HVACCCANIL MKPFESLRSN EARKREVFSA AAAAGISVAF
GAPIGGVLFS LEQLSYYFPD KTMWQSFVCA MVAAVTLQAL NPFRTGKIVL YQVTYTRGWH
RFEIIPFIFL GIIGGLYGAF LIRLNTRIAM WRRARTSSRP IIEVVVVALI TALVNYPNHF
MRAQNSELVQ SLFAECNSVT YDRFGLCATG SASIGVAIYL VVAALLAFFL ASLTFGLEIP
AGIILPSVAI GALFGRALGI IVRLWQESYP KAFPFVKCEQ DIPCVTPGLY AIIGAAAALG
GATRMTLSIV VIMFELTGAL TYVIPIMIAV MLSKWCGDIF GKRGIYESWI RLNEYLFLDH
RDDTTPPDVS AHRVMTTVDD INIITATGHT IASIRSLLAN TTYRGFPIVS DTSSPILLGY
ITRNELSFAL KYSTSPTTRN LSDDTQVFFS HQPFADPIDT LDLRPWMDQT PITLNSNITF
LIVLRMFQRL GLRYVLFANK GILQGILTKK DVWSVLNGVE FRRYEALQDD AFHNFENRNE
AEEVGLLDGN DTSSLGTADL PALEKAKKTE EKMMIDPFEV RMRFTTQLQH LSAAVTSSQK
AAHYALKYRD LDEDLHSCIL EQLERNNMNN RANIMYFIEQ LCEMAIKENY LPYVRMMQRD
ILRVVDSVVP PDGTGAANVK HVRHVLSGLQ AKEVLSAETV AEIDAALKDR DSHPSHLDLE
QDEVPEGGSK LKSEKPQLRL DKRQIEQRIE EDRERNKRQR ESMWAMTGND LDEYNQMWEE
LSPIGEDDFI RSREEALERA ECVRKHEEFY KNLHGIKEQ
//
