ID K9FJ30_PEND2 Unreviewed; 383 AA.
AC K9FJ30;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=tRNA N(3)-methylcytidine methyltransferase {ECO:0000256|PIRNR:PIRNR037755};
DE EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR037755};
GN ORFNames=PDIG_61500 {ECO:0000313|EMBL:EKV09540.1};
OS Penicillium digitatum (strain PHI26 / CECT 20796) (Green mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1170229 {ECO:0000313|EMBL:EKV09540.1, ECO:0000313|Proteomes:UP000009882};
RN [1] {ECO:0000313|Proteomes:UP000009882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI26 / CECT 20796 {ECO:0000313|Proteomes:UP000009882};
RX PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT postharvest pathogen of citrus.";
RL BMC Genomics 13:646-646(2012).
CC -!- FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase.
CC {ECO:0000256|PIRNR:PIRNR037755}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. METL family.
CC {ECO:0000256|ARBA:ARBA00009725, ECO:0000256|PIRNR:PIRNR037755}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKV09540.1}.
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DR EMBL; AKCT01000241; EKV09540.1; -; Genomic_DNA.
DR AlphaFoldDB; K9FJ30; -.
DR STRING; 1170229.K9FJ30; -.
DR eggNOG; KOG2361; Eukaryota.
DR HOGENOM; CLU_029724_1_1_1; -.
DR InParanoid; K9FJ30; -.
DR OMA; PAKYWDI; -.
DR OrthoDB; 5471626at2759; -.
DR Proteomes; UP000009882; Unassembled WGS sequence.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:UniProt.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0001510; P:RNA methylation; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR026113; METTL2/6/8-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22809:SF11; METHYLTRANSFERASE-LIKE PROTEIN; 1.
DR PANTHER; PTHR22809; METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR PIRSF; PIRSF037755; Mettl2_prd; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|PIRNR:PIRNR037755};
KW Reference proteome {ECO:0000313|Proteomes:UP000009882};
KW Transferase {ECO:0000256|PIRNR:PIRNR037755}.
FT DOMAIN 136..245
FT /note="Methyltransferase type 12"
FT /evidence="ECO:0000259|Pfam:PF08242"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 383 AA; 43771 MW; A101A03D3815EFE2 CRC64;
MTVDPSIQEV TQNVEPPQVA PHRSHDPTNN LKRTDPFQFG SRYLEKGDDV FEFNAWDHVE
PDEEFKAFAE TQYAKQRETR VSDFDRNRFN TDPAKWWDIF YKNNTANFFK DRKWLRQEFP
ILAEVTQKDA GPQVVLEVGA GAGNTAFPLL ANNENEHLKV HACDFSKYAV KVMRESELYN
EKFMSADVWD AAGVPNENGD SLPPGLTEGS VDVVILIFIF SALAPNQWDQ AIRNIYRLLK
PGGRVLFRDY GRGDLAQVRF KKGRYMAENF YIRGDGTRVY FFDQDQLVDM WGTWSAENGL
QIPIGDENPT GEVSEKKTDE LSAEAKQLAK DNGAFEVLKM GADRRLIVNR GTKQKMYRCW
MQGNFQKRGG AETETEAATE STQ
//
