ID K9GK47_PEND2 Unreviewed; 1237 AA.
AC K9GK47;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Guanyl-nucleotide exchange factor, putative {ECO:0000313|EMBL:EKV13591.1};
GN ORFNames=PDIG_37800 {ECO:0000313|EMBL:EKV13591.1};
OS Penicillium digitatum (strain PHI26 / CECT 20796) (Green mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1170229 {ECO:0000313|EMBL:EKV13591.1, ECO:0000313|Proteomes:UP000009882};
RN [1] {ECO:0000313|Proteomes:UP000009882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI26 / CECT 20796 {ECO:0000313|Proteomes:UP000009882};
RX PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT postharvest pathogen of citrus.";
RL BMC Genomics 13:646-646(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKV13591.1}.
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DR EMBL; AKCT01000159; EKV13591.1; -; Genomic_DNA.
DR AlphaFoldDB; K9GK47; -.
DR STRING; 1170229.K9GK47; -.
DR eggNOG; KOG0929; Eukaryota.
DR HOGENOM; CLU_004694_0_0_1; -.
DR InParanoid; K9GK47; -.
DR OMA; FVRHNAL; -.
DR OrthoDB; 4248238at2759; -.
DR Proteomes; UP000009882; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF402; ARF GUANINE NUCLEOTIDE EXCHANGE FACTOR SYT1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000009882};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 252..426
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT DOMAIN 548..676
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..723
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 822..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 922..942
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 983..1071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1092..1237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..98
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..721
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 828..842
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1148..1164
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1237 AA; 137377 MW; 1E53A7CE9E5FEA8E CRC64;
MEEMSRKSME QPAKSRRRGG QGSNDTQVTE STLAMSRSIT EEPGRLSINS LRGWNPQPSD
SQRSSVIDPR FSESSRSDQS YSDQTFTRSV SPRDGQSATT AKRFRIPRLT RTRSPLFPLP
PKVSHPAVCV DNGPKFPPVD TPQSENSDGY DQVTALPSPS RSPVGLAAST VSPLFRNDST
NSASSVRSNP SFKNRGRSST MGSLAENQDD LSIPPYLASS ARTSTSTSGR KSFGDMFNIT
QRLRQNSSPP FPRHGSPTIG GASTPVLRQE LPPIPKREEN DTPTSYLTRL EEALPRGMIA
CVLAQSDEEF YKICLRKHMR TFSYFGDPLD MAIRKLLMEV ELPKETQQID RFVQAFADRY
HECNPGIFTA PDNAYFIAFS LLILHTDVFN KNNKRKMQKA DYVKISRSEG ISEDVLECFY
ENISYTPFIR VEDANMPDRH LAKPRRTLFK STSSENLARI AREPVDPYSL ILEGKLESLR
PSLKDVMDLE DTYNHFGSAG PPDIDALHQD FKKSGILQII SLRSRPDAFM PASLDNPQDS
NPGLVDIKVA KVGLLWRKDP KKKKARSPWQ EWGAILTFSQ LYFFRNVNWV RSLMAQHDSF
VKNDRRGTLI FRPPLAEFKP DNILSTGETV ALLDSSYKKH KHAFIFVRHN ALEETFLASS
EPDMNDWLAH LNYAAAFRTT GVRTKGMIAT NYEGQRYRKN QRLNSVSSQK SHQSTEIEPP
SPSIDTDIVA EFVAARRKLM GHKIWERNEK LAVSQKQLDD LLQNARHLQL LTPLHARARE
GVITAAGRLS AKIKWVRQDI WRSKCYRQVL MRDLEEDEEA VESRVGSVAE PTPSQSDGAR
LASLSGPSII SEPIIEGSSS VVHTISSADT VEPNIAQTEP PSEAGLLAKP LNVELRRPSI
PGSVTSADIA RVGRRRSAVT IPKRAKSYSP DPTTTKLERE SSVLSRWDGA SLASRTSKLT
LPVSFDDGEE RVLREAGLLE LPASPLTHKD EGIAPDTLPG KNTEGETNAN DKSNRSSRVR
RSFHRSLRDS HAHRNYTHSK KKRGSISSNG QEEDDQLSGE GDVLPRKAPS FTVHGKKASI
VTFGSEWQNM PPEERLKLRK PTPHEEPRAS DLAILDSGEL ITTDRSPERP HSARRTSATT
GLSVRTSDDL AEFKDAHEEQ PEEDIGSPAS PVITSPPTLG VNPLDTAHTP HSPSSTVYGH
LSAPISNGSP SPSSTSINER IADTPSSENL REQAVGA
//
