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Database: UniProt
Entry: K9GQ59_9PROT
LinkDB: K9GQ59_9PROT
Original site: K9GQ59_9PROT 
ID   K9GQ59_9PROT            Unreviewed;       494 AA.
AC   K9GQ59;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   16-JAN-2019, entry version 42.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=C882_2087 {ECO:0000313|EMBL:EKV26864.1};
OS   Caenispirillum salinarum AK4.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Caenispirillum.
OX   NCBI_TaxID=1238182 {ECO:0000313|EMBL:EKV26864.1, ECO:0000313|Proteomes:UP000009881};
RN   [1] {ECO:0000313|EMBL:EKV26864.1, ECO:0000313|Proteomes:UP000009881}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AK4 {ECO:0000313|EMBL:EKV26864.1,
RC   ECO:0000313|Proteomes:UP000009881};
RX   PubMed=23409257;
RA   Khatri I., Singh A., Korpole S., Pinnaka A.K., Subramanian S.;
RT   "Draft Genome Sequence of an Alphaproteobacterium, Caenispirillum
RT   salinarum AK4(T), Isolated from a Solar Saltern.";
RL   Genome Announc. 1:E00199-12(2013).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EKV26864.1}.
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DR   EMBL; ANHY01000022; EKV26864.1; -; Genomic_DNA.
DR   EnsemblBacteria; EKV26864; EKV26864; C882_2087.
DR   PATRIC; fig|1238182.3.peg.4041; -.
DR   Proteomes; UP000009881; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000009881};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009881}.
FT   DOMAIN      191    319       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      402    471       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     199    206       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   494 AA;  54523 MW;  16BA65BDC05E2A5F CRC64;
     MDAAIAAQWD RVQGQLREEF GDAAFKSWVA PMTVTDVRDG AVTLAVPTRF IRDWVLTHYA
     DRIRALWNGE NPAVRTVDVM VVTNMQRPDL TGGGPAAAAV NDPVPGSPRA AAMESGRRTE
     AAAAGRAGTP ASAAAPVPAH GGFMAAAPTG QVDDLSASLD ARYTFENFVV GKPNEFAHAA
     AQRVADSDQV SFNPLFLYGG VGLGKTHLMH AIAHRLRERR PERRVIYMSA EKFMYSFVRA
     LRHQDTISFK EQFRTVDVLM IDDVQFISGK DSTQEEFFHT FNALVDQGRQ IVISADKSPN
     DLEEIGARLR SRMASGLVAD IHPTTYELRL GILDAKAEQM GVEVPVKVKE FLAHKITSNA
     RELEGALTRL VAHAQLVGRE LSLETAHDVL ADLLRAYDRR VTIEEIQKKV AEHFQVRVAD
     MHSARRARAV TRPRQVAMYL SKQLTSRSLP EIGRKFGGRD HTTVMHAVKK VEELIAGDAA
     FAEDVNLLRR MLES
//
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