ID K9H2D8_9PROT Unreviewed; 515 AA.
AC K9H2D8;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:EKV32435.1};
GN ORFNames=C882_2514 {ECO:0000313|EMBL:EKV32435.1};
OS Caenispirillum salinarum AK4.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Novispirillaceae; Caenispirillum.
OX NCBI_TaxID=1238182 {ECO:0000313|EMBL:EKV32435.1, ECO:0000313|Proteomes:UP000009881};
RN [1] {ECO:0000313|EMBL:EKV32435.1, ECO:0000313|Proteomes:UP000009881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK4 {ECO:0000313|EMBL:EKV32435.1,
RC ECO:0000313|Proteomes:UP000009881};
RX PubMed=23409257;
RA Khatri I., Singh A., Korpole S., Pinnaka A.K., Subramanian S.;
RT "Draft Genome Sequence of an Alphaproteobacterium, Caenispirillum salinarum
RT AK4(T), Isolated from a Solar Saltern.";
RL Genome Announc. 1:E00199-12(2013).
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC {ECO:0000256|ARBA:ARBA00005381}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKV32435.1}.
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DR EMBL; ANHY01000003; EKV32435.1; -; Genomic_DNA.
DR RefSeq; WP_009538923.1; NZ_ANHY01000003.1.
DR AlphaFoldDB; K9H2D8; -.
DR STRING; 1238182.C882_2514; -.
DR PATRIC; fig|1238182.3.peg.474; -.
DR eggNOG; COG2114; Bacteria.
DR OrthoDB; 9762462at2; -.
DR Proteomes; UP000009881; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR048440; MASE10.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF20970; MASE10; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009881};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 62..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 239..291
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 327..459
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 515 AA; 54665 MW; DFC9572173140C76 CRC64;
MTAATTASAA AGSLPAPRTL WHALPRADAL KAHASIVPAS LFLAVYNQFV CPFMDGLPFL
TLLEGLAVVM AVQIVLRQIL WVYWPAPQSV SLARHGWRIA VISWGIAGLK AMTLHGLTYE
AYPLLSYLKL ATGFWILGAG LIAQFEYTLL EDMLRKRGAE GAAADESPGA TARRLEERIV
RRLTESASSF AVAPAAALVM MAVRQVEEGY AEPVIVVEVL FIAAVFVGAA LLVAGHYGRS
LRRDTVAIVD SLDAVSGGRF DVCLDASRPD ELGRVAGGIN TMAAGLRQRE RIRDAFGRFV
SPEVAETVLA EAAEGAVRLH GERRHVAVLM CDLRDFTPLA ERLEPEEVTA LLNGYFAEMV
AAVHAHHGMV DKFIGDAVMA VFGLAPCPQG RTPERLAVDA ALEMRARLAA FNAAHPNRPP
LSHGIGIHAG PAVAGTIGSP DRLEFTVIGS TVNLAARLEA ETRAVGEPIL MSEAVAAHLN
GAARPVGTGS LKGLSRPVAL FAPQAATPTP LLPSY
//
