ID   K9NFC3_9PSED            Unreviewed;      1061 AA.
AC   K9NFC3;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=PputUW4_00646 {ECO:0000313|EMBL:AFY17853.1};
OS   Pseudomonas sp. UW4.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=1207075 {ECO:0000313|EMBL:AFY17853.1, ECO:0000313|Proteomes:UP000010397};
RN   [1] {ECO:0000313|EMBL:AFY17853.1, ECO:0000313|Proteomes:UP000010397}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UW4 {ECO:0000313|EMBL:AFY17853.1,
RC   ECO:0000313|Proteomes:UP000010397};
RX   PubMed=23516524;
RA   Duan J., Jiang W., Cheng Z., Heikkila J.J., Glick B.R.;
RT   "The Complete Genome Sequence of the Plant Growth-Promoting Bacterium
RT   Pseudomonas sp. UW4.";
RL   PLoS ONE 8:E58640-E58640(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP003880; AFY17853.1; -; Genomic_DNA.
DR   RefSeq; WP_015093391.1; NC_019670.1.
DR   AlphaFoldDB; K9NFC3; -.
DR   STRING; 1207075.PputUW4_00646; -.
DR   KEGG; ppuu:PputUW4_00646; -.
DR   PATRIC; fig|1207075.3.peg.667; -.
DR   eggNOG; COG1074; Bacteria.
DR   HOGENOM; CLU_001114_1_2_6; -.
DR   OrthoDB; 9810135at2; -.
DR   Proteomes; UP000010397; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.320.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011604; PDDEXK-like_dom_sf.
DR   InterPro; IPR038726; PDDEXK_AddAB-type.
DR   InterPro; IPR011335; Restrct_endonuc-II-like.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF23; RECBCD ENZYME SUBUNIT RECB; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF12705; PDDEXK_1; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          1..410
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   DOMAIN          415..706
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51217"
FT   BINDING         12..19
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   1061 AA;  117076 MW;  2E472B13B980DF50 CRC64;
     MQTTAHITFI SAGAGSGKTH RLTEILHQEL LDQQVQPSGV IATTFTRKAA AELRERVRSH
     LLKQGQINLA TAMGQARIGT VNSICGQLLE RFAFEAGMPP EQRVLEENQA ALLLNKAVDR
     VLDGERLDNL LAVARRLGLE DTYQQGDFAN TNWRDELRKL LNQLRTNDID LELSRGFAAQ
     NADDMLKHFP KPTKTDLSGE LLHSIPEVLA LLQAANSDKK NTEGYIALLT RFQYELQHDN
     ARWSDWAKLA KEAPEAKLKP LVTTLSETIG RYAEHPDLHR DIRAYLEQVF GLAIDVLKVY
     EHSKREFGVL DFADQEHALL KLLDNPAVAQ VLEDELDLIM VDEFQDTSPM QLAIFLKLSR
     FAKKVYWVGD IKQAIYGFRG SDCALMQAIL KALPDMGGKK QVLPNSWRSR TELVELANDV
     FNKAFANSLE TKDVELIPTR TDQLPGPAFA NWVLDGKNAD LQVNALAEGI GQLLASRYQV
     FDKTRQEARA VRLGDITVLC YSHSNVAKVT AALATLGIPC STAQPGLLAT AEATLALACL
     RRLNDPADTL ATAQIISLTE TEGPESWVAE RLRYLNAGHP KAQWRELSLG EYSQHPLVAA
     VAQLRTDLPV LTPVEALQRL IAECDLPTRV SVWSTSTAQV QKRLANLDAL IDLAQQYEDL
     CRNGLGAASI SGLLLWLDEI ANAKNDALAT PALDAVQVMT HHASKGLEWP VVILMDHARD
     ISDRLWSVSA QSNSAFDPHK PLHDRFIRYW PWPLGKQKAV PLSETFEQTA TGLACRAEAV
     EEAKRLLYVS MTRARDLLVI ARSSRKITGE WLDTVQAPWL MTPPGLSTLK LPNGKELCAD
     CQTLTASDLP APVAIIEQNL HWFAPVQAVQ SRLPLGFQPS NGGARASTAG RNTCRIGTRI
     AFQGSPEMSA LGTAIHASLC LSFTDPNCPL TLDEVQYLLQ SHAVHEHINA SQVIAQQLAL
     HAWIESRWPA AKAMAEYPVQ QLLRSGQVLN GRIDLLLDTK DGWVLIDHKS NPAPEAQWER
     LAEEHAGQLD AYAQAIEAAS GRPVIAAWLF LPVAAGAIQV F
//