ID K9P4J2_CYAGP Unreviewed; 715 AA.
AC K9P4J2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein {ECO:0000313|EMBL:AFY27474.1};
GN OrderedLocusNames=Cyagr_0273 {ECO:0000313|EMBL:AFY27474.1};
OS Cyanobium gracile (strain ATCC 27147 / PCC 6307).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Prochlorococcaceae; Cyanobium.
OX NCBI_TaxID=292564 {ECO:0000313|EMBL:AFY27474.1, ECO:0000313|Proteomes:UP000010388};
RN [1] {ECO:0000313|Proteomes:UP000010388}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27147 / PCC 6307 {ECO:0000313|Proteomes:UP000010388};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003495; AFY27474.1; -; Genomic_DNA.
DR RefSeq; WP_015107933.1; NC_019675.1.
DR AlphaFoldDB; K9P4J2; -.
DR STRING; 292564.Cyagr_0273; -.
DR KEGG; cgc:Cyagr_0273; -.
DR PATRIC; fig|292564.3.peg.249; -.
DR eggNOG; COG2274; Bacteria.
DR HOGENOM; CLU_000604_95_3_3; -.
DR OrthoDB; 516912at2; -.
DR Proteomes; UP000010388; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR022514; NHPM_micro_ABC1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005074; Peptidase_C39.
DR InterPro; IPR039421; Type_1_exporter.
DR NCBIfam; TIGR03796; NHLM_micro_ABC1; 1.
DR PANTHER; PTHR24221:SF658; ABC TRANSPORTER B FAMILY MEMBER 29, CHLOROPLASTIC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF03412; Peptidase_C39; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50990; PEPTIDASE_C39; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:AFY27474.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..129
FT /note="Peptidase C39"
FT /evidence="ECO:0000259|PROSITE:PS50990"
FT DOMAIN 160..418
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 480..713
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 715 AA; 78394 MW; 9E4C4BD6F1E30A9C CRC64;
MKHTPTVLQM ETTECGAASL AVILQHHGRH VPMSQLRDAC CVSRDGTNAA AIQAAARLYG
LEVDGFMAED TKDLRRWERP VILHWQFNHF LVLEGISGRN VMLNDPAIGR RRVTLAEFER
SFTGVFLDLK PGSSFRRGGH PPRFWGAIAQ RLALEKAGVL FTLITGLLLV LPQVLIPVFS
QVYIDEIWGQ GMQAWLKPML WALVLVLLLQ TLLKHLQLTA IRRLTRRLDS RFSAQFERHV
LSLPERYFSQ RYAGDINGRV ELNREVASFL AEQLIPLLSG VMLLVFYLVL TLSYSPWLGG
VVGISTGLNA LLVAFTHHAH QEDSLRLQQD GAKAQSVVTA AIRDIETVKT AAVETDLATR
YGGHLSTALN GSQRIGLRQA RLELVPGLLN QVNNLAVLIV GFVLLLRGEM TLGMVLAAQQ
VSGGLKGEVD RWVAFVRELP TMQASLLRLE DVLGEPVDPL VNGRLCSMDS EGGSRLSGAI
TLEAMSFGYI PTQQPLLGPI DLRVAPGQRL ALVGGSGSGK STLARLLAGL ERPDVGEILY
DGHALEAIPR SVAVGSIALV QQEVQLYGVS VRDNLTLWNQ AIPHEQLEEA CRDAQILDDI
RKLPQGFDTL LSEGGQSLSG GQRQRLEIAR ALVQNPAILI LDEASSALDA ITEQRLSEAL
RRRGCTQIVI AHRLSAIRDA DQILVLEHGR VVQRGRHEDL LTDSSGVYAG LVADE
//
