ID K9QJK5_9NOSO Unreviewed; 466 AA.
AC K9QJK5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Magnesium transporter MgtE {ECO:0000256|RuleBase:RU362011};
GN ORFNames=Nos7107_5058 {ECO:0000313|EMBL:AFY45573.1};
OS Nostoc sp. PCC 7107.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=317936 {ECO:0000313|EMBL:AFY45573.1, ECO:0000313|Proteomes:UP000010381};
RN [1] {ECO:0000313|EMBL:AFY45573.1, ECO:0000313|Proteomes:UP000010381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7107 {ECO:0000313|EMBL:AFY45573.1,
RC ECO:0000313|Proteomes:UP000010381};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished genome of Nostoc sp. PCC 7107.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a magnesium transporter.
CC {ECO:0000256|RuleBase:RU362011}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|RuleBase:RU362011}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362011};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362011}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC {ECO:0000256|ARBA:ARBA00009749, ECO:0000256|RuleBase:RU362011}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362011}.
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DR EMBL; CP003548; AFY45573.1; -; Genomic_DNA.
DR RefSeq; WP_015115761.1; NC_019676.1.
DR AlphaFoldDB; K9QJK5; -.
DR KEGG; nos:Nos7107_5058; -.
DR PATRIC; fig|317936.3.peg.5491; -.
DR eggNOG; COG2239; Bacteria.
DR HOGENOM; CLU_037408_2_2_3; -.
DR InParanoid; K9QJK5; -.
DR OrthoDB; 9790355at2; -.
DR Proteomes; UP000010381; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04606; CBS_pair_Mg_transporter; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.25.60.10; MgtE N-terminal domain-like; 1.
DR Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR006668; Mg_transptr_MgtE_intracell_dom.
DR InterPro; IPR038076; MgtE_N_sf.
DR InterPro; IPR006669; MgtE_transporter.
DR InterPro; IPR006667; SLC41_membr_dom.
DR InterPro; IPR036739; SLC41_membr_dom_sf.
DR NCBIfam; TIGR00400; mgtE; 1.
DR PANTHER; PTHR43773; MAGNESIUM TRANSPORTER MGTE; 1.
DR PANTHER; PTHR43773:SF1; MAGNESIUM TRANSPORTER MGTE; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01769; MgtE; 1.
DR Pfam; PF03448; MgtE_N; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM00924; MgtE_N; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF161093; MgtE membrane domain-like; 1.
DR SUPFAM; SSF158791; MgtE N-terminal domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Cell membrane {ECO:0000256|RuleBase:RU362011};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|RuleBase:RU362011};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362011};
KW Metal-binding {ECO:0000256|RuleBase:RU362011};
KW Reference proteome {ECO:0000313|Proteomes:UP000010381};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362011};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362011};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362011}.
FT TRANSMEM 302..319
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT TRANSMEM 376..396
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT TRANSMEM 403..429
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT TRANSMEM 441..464
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT DOMAIN 153..216
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 217..275
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 466 AA; 51474 MW; 7807C63E4BD87C7D CRC64;
MTETNNLNSS FPDVSRRELR DLVRTQLQML LESADLQAAK AILVPVQPAD IAEAIEGLPE
AMHALAFRLL SKDEAIAVYE YLDYSVQERL IEELKSQEVR DIVDQMSSDD RARLFDELPA
KVVNRLLEQL SPVERQATAL LLGYEPNTAG RIMTLEFISL KENITVTQAL ERIRRLASAS
EIIYYLYVTD ADRRLTGIVS LRDVVTSQPE QIIGEIMTRD VVFVRTDTDQ EEVARIIQRY
DFLAVPVVDK QQLLVGIVTV DDVIDILEEE TTKDIYALGG GVQSSGDNYF QMNLMEVARK
RVLWLFVLLI TNTVTGTIIK SQEDILTKVV TLTAFIPLLT GTGGNVGAQS STVVIRGMNT
DEIRSLGPLQ VIGREAIAGL LLGGMLGIVA TVWAYFLQGR IEVAIAVGSS LVAISILASV
SGSALPFLFR MLRLDPALMS APFITTAVDV LGVLIYFNLA RVILKL
//
