ID K9R5Q2_9CYAN Unreviewed; 350 AA.
AC K9R5Q2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000256|HAMAP-Rule:MF_01391};
GN Name=ccsA {ECO:0000256|HAMAP-Rule:MF_01391};
GN ORFNames=Riv7116_0665 {ECO:0000313|EMBL:AFY53255.1};
OS Rivularia sp. PCC 7116.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Rivulariaceae;
OC Rivularia.
OX NCBI_TaxID=373994 {ECO:0000313|EMBL:AFY53255.1, ECO:0000313|Proteomes:UP000010380};
RN [1] {ECO:0000313|EMBL:AFY53255.1, ECO:0000313|Proteomes:UP000010380}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7116 {ECO:0000313|EMBL:AFY53255.1,
RC ECO:0000313|Proteomes:UP000010380};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Chen A., Kyrpides N.,
RA Mavromatis K., Markowitz V., Szeto E., Ivanova N., Pagani I., Pati A.,
RA Goodwin L., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T., Kerfeld C.A.;
RT "Finished chromosome of genome of Rivularia sp. PCC 7116.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC c6 and cytochrome f) at the step of heme attachment.
CC {ECO:0000256|HAMAP-Rule:MF_01391}.
CC -!- SUBUNIT: May interact with Ccs1. {ECO:0000256|HAMAP-Rule:MF_01391}.
CC -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000256|HAMAP-
CC Rule:MF_01391}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_01391}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000256|HAMAP-Rule:MF_01391}.
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DR EMBL; CP003549; AFY53255.1; -; Genomic_DNA.
DR RefSeq; WP_015116833.1; NC_019678.1.
DR AlphaFoldDB; K9R5Q2; -.
DR STRING; 373994.Riv7116_0665; -.
DR KEGG; riv:Riv7116_0665; -.
DR PATRIC; fig|373994.3.peg.695; -.
DR eggNOG; COG0755; Bacteria.
DR HOGENOM; CLU_049710_2_2_3; -.
DR OrthoDB; 9814290at2; -.
DR Proteomes; UP000010380; Chromosome.
DR GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01391; CytC_CcsA; 1.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR NCBIfam; TIGR03144; cytochr_II_ccsB; 1.
DR PANTHER; PTHR30071:SF1; CYTOCHROME B_B6 PROTEIN-RELATED; 1.
DR PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
PE 3: Inferred from homology;
KW Cytochrome c-type biogenesis {ECO:0000256|ARBA:ARBA00022748,
KW ECO:0000256|HAMAP-Rule:MF_01391};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01391};
KW Reference proteome {ECO:0000313|Proteomes:UP000010380};
KW Thylakoid {ECO:0000256|HAMAP-Rule:MF_01391};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01391};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01391}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 70..89
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 96..115
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 135..163
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 254..277
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 292..307
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 319..340
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT DOMAIN 68..344
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
SQ SEQUENCE 350 AA; 38027 MW; 70E54CF6DC64A925 CRC64;
MDLVVLQNWL DNASFLVLFL TMLIYWVGAA FPNIPTLAGL GTAGMAIANL CMATLLGARW
LEGGYFPLSN LYESLFFLAW GITTVHLIAE YSSRSRLVGV ATAPVAMGIT AFAALTLPSE
MQVSEPLVPA LKSNWLMMHV SVMMLSYSAL MVGSLVAVAF LIVTKGQQVQ LQGSSVGNGG
YRSNGYRLHK AGELVTEPNA FAFENNGFSP VQSNSNGKSA TAVARRIETS QNVENSGEPL
SPQRLSLAET LDNISYRIIG LGFPLLTIGI IAGAVWANEA WGSYWSWDPK ETWALICWLV
FAAYLHARIT RGWQGRRPAI LAATGFVAVW VCYLGVNLLG KGLHSYGWFF
//
