ID K9SEE0_9CYAN Unreviewed; 594 AA.
AC K9SEE0;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:AFY68149.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:AFY68149.1};
DE Flags: Precursor;
GN ORFNames=GEI7407_3682 {ECO:0000313|EMBL:AFY68149.1};
OS Geitlerinema sp. PCC 7407.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Geitlerinematales;
OC Geitlerinemataceae; Geitlerinema.
OX NCBI_TaxID=1173025 {ECO:0000313|EMBL:AFY68149.1, ECO:0000313|Proteomes:UP000010383};
RN [1] {ECO:0000313|EMBL:AFY68149.1, ECO:0000313|Proteomes:UP000010383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7407 {ECO:0000313|EMBL:AFY68149.1,
RC ECO:0000313|Proteomes:UP000010383};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished genome of Geitlerinema sp. PCC 7407.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; CP003591; AFY68149.1; -; Genomic_DNA.
DR RefSeq; WP_015173713.1; NC_019703.1.
DR AlphaFoldDB; K9SEE0; -.
DR STRING; 1173025.GEI7407_3682; -.
DR KEGG; gei:GEI7407_3682; -.
DR PATRIC; fig|1173025.3.peg.4118; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_1_2_3; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000010383; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:AFY68149.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000010383};
KW Transferase {ECO:0000313|EMBL:AFY68149.1}.
FT DOMAIN 71..238
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 274..586
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 594 AA; 63609 MW; 3B2752B663D61896 CRC64;
MARGLSFSPG LARKRAVTAT PPSARSLRAI ALLIAVTAPL MVCTFRLAQL QLIEGKYNRL
LAEDNRVRFV PIPADRGNIF DRNGKLLATN RLTRAVYLWP RQQSPEQWYA SAQRLGKILG
LEPQEILKKL EEAGFASSLP VRITRDLSPT EFIGLAEFAG QMPGLEIRGE AARNYPNGSV
AAHMLGYIGE ATADDLKEHP EYPMGMLLGK MGLERTINKV LQGKWGNRLV EVDAAGKERR
ILGYQSPVGG ESVKLTVDIA LQKAAEAALG GRRGSVVVLD AKTGAVLTMV SHPTFDPNLF
TRKVSASEWE QLQASDNPFL NRSLQGYPPG STFKIVTSAA AMGSGQFSPD SMLVSSAAIT
VGGISFHEHG NSGYGLIGFR DALAYSSNTF FYQVGLAIGP EQISKWGKAL GIGATDLSLL
GLDGGSHGSL PTPKEKQELY DEPWYAGDTV TMSIGQGLAL MTPLEMAVMV SAIANGGWRV
KPHLLTAQTN TPQTAREKVG LSPEEIAVIR EGLIAVVQKG TARQLNDGTI PLTGGKTGTV
EVLGQEDNSM YVGFAPANDP KIAISVVIEE GGYGATSAVP VAQAVYRAYF SQKR
//
