ID K9TGI8_9CYAN Unreviewed; 1818 AA.
AC K9TGI8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Oscil6304_2349 {ECO:0000313|EMBL:AFY81977.1};
OS Oscillatoria acuminata PCC 6304.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Oscillatoria.
OX NCBI_TaxID=56110 {ECO:0000313|EMBL:AFY81977.1, ECO:0000313|Proteomes:UP000010367};
RN [1] {ECO:0000313|EMBL:AFY81977.1, ECO:0000313|Proteomes:UP000010367}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6304 {ECO:0000313|EMBL:AFY81977.1,
RC ECO:0000313|Proteomes:UP000010367};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished chromosome of genome of Oscillatoria acuminata PCC 6304.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP003607; AFY81977.1; -; Genomic_DNA.
DR RefSeq; WP_015148619.1; NC_019693.1.
DR STRING; 56110.Oscil6304_2349; -.
DR KEGG; oac:Oscil6304_2349; -.
DR PATRIC; fig|56110.3.peg.2789; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG3899; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR HOGENOM; CLU_000445_34_1_3; -.
DR InParanoid; K9TGI8; -.
DR OrthoDB; 573511at2; -.
DR Proteomes; UP000010367; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000010367}.
FT DOMAIN 18..278
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1569..1818
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 1530..1560
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1818 AA; 203678 MW; 2A04EC8A9492CFCF CRC64;
MKNPEMMTGQ SHPQLPDYTL TELIYPGTRT HVYRGVHQQS QQPVVIKVMK RDYPTFGELV
QFRNQFVITK NLQIPGIVRT LALEVFGNGY AIVMEDSGSI SMEQYLENQS LNLLKILDIA
IQLTTILHDL HHHRIIHKDI KPANVLIHPN SRQITLIDFS IASLLPKETQ EIQSPQGLEG
TLAYLAPEQT GRMNRGIDYR ADFYALGVML YELLTGQLPF RSDDPLEVIH SHIAKTPTPV
HEVNPEIPAM LEAIVAKLMA KNAEDRYQSA LGLQHDLREC LNQWQTRGEI SEFVLGQRDL
SDRFNIPEKL YGRETEVQAL LKAFERVSQG ASELMLVAGF SGIGKTAVVN EVHKPITEQK
GYFIKGKFDQ FNRNIPLSAF VQALRDLIGQ LLCESDVELA QWQAQILEAV GENGQVLIEV
IPELEQVMGQ QPPTPELSGS AVQNRFNLLF QKFIQVFTTA AHPLVIFLDD LQWADAASLQ
LLKVLMDDNG YLLVLGAYRD NEVSPAHPLM LTIAELKKAN FTVNTITLAP LSLEHTNHLI
ADTLKCSRER AQSLTQLVDR KTQGNPFFTT QFLKALHEDG YITFERNQGY WQCDIAQVNA
LALTDDVVEF MALQLQKLPG ETQQILKLAA CIGNQFDLAT LAIVAEQSLT EAATALWNSL
QEGLIVPITQ IYKFFHAEEI ESADVHNSIT PVYRFLHDRI QQAAYSLIPE DQKQWTHYHI
GQLLLKQTSP TTREEQVFEL VNQLNHGISL ITHPSEQFEL AQLNLIAAQK ARAAAAYEAA
QNYVTLGLAL LGEEAWEDHY EIILVLYELA AEIAFLIGDF PQMEAWINTV IAQAHNLLDK
INVYQIQIQS IVSQAKFAEA LIIAQEILQE LGITFMATPT FADIQKEIQE ITELMGDREI
IDLLHLPENV DQLKLAIIQM TTGVAPAAYL SGSPLFPFLI SCAVKLSIQS GNTADSALAY
SLYSIVTCNF LQDVDTATAF SQLALQLVAK LDAKAVKPEI YSAVGLYILH RKSPVTATLP
LFFEGYTAAL EVGNLEYVAF NANEFCTYSF WCGQPLTTLE QESRDYCQAL VNLNQLGVAN
YCCLCWQSTL NLLGRSDDPT LIAGEAIQET ELLPFMLSAH DLAGLYFFYL YKLVLCYLFG
KIDLANHDAL EIRNYLMAGA GTLGEAVFYF YDSLIALAQL PSVTEEQAST LEERVERNQT
QLQFWAHHAP MNHQHKVDLV SAERCRVLGQ SYEAGNYYDR AIARAKENSY IQEEALANEL
AAKFYLDWGK EKVAAGYMQE AYYCYARWGA KAKVEDLEKR YPQLLQPILQ AANQPLTVLE
TLTSIATSSV YSIHATSSKS ESSSSINQTL DFAALLQISQ TFASTIALDE LLQTLTQTML
ENSGADRCAL MLCEDKQWQV RVLANLKQVT LQSAPLNDNP NVPVKLIQYV KNTVTTVVLD
ALKTDLPVIG DYLHRHQPKS VLCLPILNQG NLLAILYLEN RSASGVFTGD RIVILNFLCT
QAAISLENAS LYQKVSNYSH TLEAEVVRQT QVLHQKNQEL EQILKNLQQT QAQLIQNEKM
SSLGQLVAGI AHEINNPINF IKGNIAPLEN YWKDLKNLVN LYREDGCQPS ESLQMKQEEV
DLEFLFRDVE KILKSMTTGS ERIQQIVLSL RNFSRLDESS TKAVDLHSGI DSTLLILQHR
LQQIGDSPEI QVVCDYGDLP RITCYPSQLN QVFLNIINNA IDAIRENSKC SDHPQIRIRT
EPLAQKGIRI AIANTDSRIP PEIQDRIFDP FFTTKPVGSG TGLGLFVSYS IIQKHGGTLR
VRSPSSGGAE FEIILPCG
//
