ID K9TM17_9CYAN Unreviewed; 357 AA.
AC K9TM17;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000256|HAMAP-Rule:MF_01391};
GN Name=ccsA {ECO:0000256|HAMAP-Rule:MF_01391};
GN ORFNames=Oscil6304_4049 {ECO:0000313|EMBL:AFY83580.1};
OS Oscillatoria acuminata PCC 6304.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Oscillatoria.
OX NCBI_TaxID=56110 {ECO:0000313|EMBL:AFY83580.1, ECO:0000313|Proteomes:UP000010367};
RN [1] {ECO:0000313|EMBL:AFY83580.1, ECO:0000313|Proteomes:UP000010367}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6304 {ECO:0000313|EMBL:AFY83580.1,
RC ECO:0000313|Proteomes:UP000010367};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished chromosome of genome of Oscillatoria acuminata PCC 6304.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC c6 and cytochrome f) at the step of heme attachment.
CC {ECO:0000256|HAMAP-Rule:MF_01391}.
CC -!- SUBUNIT: May interact with Ccs1. {ECO:0000256|HAMAP-Rule:MF_01391}.
CC -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000256|HAMAP-
CC Rule:MF_01391}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_01391}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000256|HAMAP-Rule:MF_01391}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003607; AFY83580.1; -; Genomic_DNA.
DR RefSeq; WP_015150204.1; NC_019693.1.
DR AlphaFoldDB; K9TM17; -.
DR STRING; 56110.Oscil6304_4049; -.
DR KEGG; oac:Oscil6304_4049; -.
DR PATRIC; fig|56110.3.peg.4902; -.
DR eggNOG; COG0755; Bacteria.
DR HOGENOM; CLU_049710_2_4_3; -.
DR InParanoid; K9TM17; -.
DR OrthoDB; 9814290at2; -.
DR Proteomes; UP000010367; Chromosome.
DR GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01391; CytC_CcsA; 1.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR NCBIfam; TIGR03144; cytochr_II_ccsB; 1.
DR PANTHER; PTHR30071:SF1; CYTOCHROME B_B6 PROTEIN-RELATED; 1.
DR PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
PE 3: Inferred from homology;
KW Cytochrome c-type biogenesis {ECO:0000256|ARBA:ARBA00022748,
KW ECO:0000256|HAMAP-Rule:MF_01391};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01391};
KW Reference proteome {ECO:0000313|Proteomes:UP000010367};
KW Thylakoid {ECO:0000256|HAMAP-Rule:MF_01391};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01391};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01391}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 70..89
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 96..115
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 135..163
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 261..284
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 299..314
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 326..347
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT DOMAIN 68..351
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
SQ SEQUENCE 357 AA; 38708 MW; C4A1A3DB66594D2D CRC64;
MDLSSLQNWL DNTSFCVLFI TMLLYWIGAA FPGIPALWPL GTSGMAIANL CIATLLGARW
IEAGYFPLSN LYESLFFLVW GITTIHLIAE NMSRSRLVGV ATSPVAMAIT AFAALTLPGE
MQQSAPLVPA LKSNWLMMHV SVMMLSYATL MVGSLLAIAF LFVTRGQNIE LRGSSIGNGS
YRSDRYRLQR AGTPIPAVEG PTPTPEFATG FSGNNNGKGL GGNVALLDVV QVDSNAQPAT
PTLQPALSPQ RLSLADTLDN ISYRIIGLGF PLLTIGIIAG GVWANEAWGS YWSWDPKETW
ALITWLVFAA YLHARITRGW QGRKPAILAA AGFVVVWICY LGVNLLGKGL HSYGWFF
//
