ID K9VJV1_9CYAN Unreviewed; 604 AA.
AC K9VJV1;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:AFZ07505.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:AFZ07505.1};
GN ORFNames=Osc7112_3116 {ECO:0000313|EMBL:AFZ07505.1};
OS Oscillatoria nigro-viridis PCC 7112.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Oscillatoria.
OX NCBI_TaxID=179408 {ECO:0000313|EMBL:AFZ07505.1, ECO:0000313|Proteomes:UP000010478};
RN [1] {ECO:0000313|EMBL:AFZ07505.1, ECO:0000313|Proteomes:UP000010478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7112 {ECO:0000313|EMBL:AFZ07505.1,
RC ECO:0000313|Proteomes:UP000010478};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished chromosome of genome of Oscillatoria sp. PCC 7112.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003614; AFZ07505.1; -; Genomic_DNA.
DR RefSeq; WP_015176783.1; NC_019729.1.
DR AlphaFoldDB; K9VJV1; -.
DR STRING; 179408.Osc7112_3116; -.
DR KEGG; oni:Osc7112_3116; -.
DR PATRIC; fig|179408.3.peg.3825; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_1_2_3; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000010478; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:AFZ07505.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010478};
KW Transferase {ECO:0000313|EMBL:AFZ07505.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 74..242
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 276..588
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 604 AA; 65011 MW; 443C99A312DACB0A CRC64;
MAGDFSFNSQ VRFDKNALDN ASRQRSRSLQ VMIFMLLVTT LVTLPIFRLA ELQLVQGAYN
RQRAENNRIR PVSVAANRGQ ILDRNGKIFA ANRVSRSVYV WPKERSAKEW QEIAATLGPI
VKLPAAEIIK KIDAAGYRSA LPVRISKDID VGTFVALGEQ SNALRGVEIR VESSRDNPNQ
QLAAHLLGYV GEATLEELKA NPGYPMGMIV GQMGVEKLAN STLEGVWGNR LIEVNAKGEE
IQDLGVKDPI PGKPVQLTLD LDMQKTAEKA LGNRLGAVVA IDVKTGALLT MASWPTFDPN
IFTRKVTQQE WDRLQGPDKP FLNRAVQGYP VGSTFKIVTS VAGMESGKFS PDSTLVSSAS
INIGGISFNE HGAGYGLIGF RDALAYSSNT FFYQVGMAAG PEQMAKWAKK MGIGGTINLD
LLGIDGANHG QVPIPAEKQK MYGEDWYVGD TVTMAIGQGL VLCTPLELAV MVSTIANGGW
RVQPHLLASQ TNTPVTKKIS TGIKPATLNV VKQGLIDVVK KGTGRAMNDG TIPLSAGKTG
TVEMPGHPDN SMYVGFAPAD KPEVAIAVIV EGGGYGAVSA APIAQEVFRT YFQKQGFKPT
NKPL
//
