ID K9VNF8_9CYAN Unreviewed; 2163 AA.
AC K9VNF8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Osc7112_4472 {ECO:0000313|EMBL:AFZ08770.1};
OS Oscillatoria nigro-viridis PCC 7112.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Oscillatoria.
OX NCBI_TaxID=179408 {ECO:0000313|EMBL:AFZ08770.1, ECO:0000313|Proteomes:UP000010478};
RN [1] {ECO:0000313|EMBL:AFZ08770.1, ECO:0000313|Proteomes:UP000010478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7112 {ECO:0000313|EMBL:AFZ08770.1,
RC ECO:0000313|Proteomes:UP000010478};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished chromosome of genome of Oscillatoria sp. PCC 7112.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SIMILARITY: In the N-terminal section; belongs to the phytochrome
CC family. {ECO:0000256|ARBA:ARBA00006402}.
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DR EMBL; CP003614; AFZ08770.1; -; Genomic_DNA.
DR RefSeq; WP_015178010.1; NC_019729.1.
DR STRING; 179408.Osc7112_4472; -.
DR KEGG; oni:Osc7112_4472; -.
DR PATRIC; fig|179408.3.peg.5553; -.
DR eggNOG; COG0745; Bacteria.
DR eggNOG; COG0784; Bacteria.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_114_65_3; -.
DR OrthoDB; 433983at2; -.
DR Proteomes; UP000010478; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 8.
DR CDD; cd00156; REC; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 9.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR016132; Phyto_chromo_attachment.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 8.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 4.
DR Pfam; PF08448; PAS_4; 2.
DR Pfam; PF13426; PAS_9; 2.
DR Pfam; PF00072; Response_reg; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 8.
DR SMART; SM00091; PAS; 9.
DR SMART; SM00448; REC; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 2.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 9.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 5.
DR PROSITE; PS50112; PAS; 7.
DR PROSITE; PS50046; PHYTOCHROME_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AFZ08770.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000010478};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 15..137
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 185..228
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 232..284
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 285..355
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 356..408
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 553..602
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 770..811
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 892..966
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 971..1024
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1195..1267
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1271..1323
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1320..1362
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1391..1443
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1463..1599
FT /note="Phytochrome chromophore attachment site"
FT /evidence="ECO:0000259|PROSITE:PS50046"
FT DOMAIN 1647..1924
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1949..2065
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 72
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 1998
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 2163 AA; 244352 MW; 35C4EA4CCA2D5299 CRC64;
MISVLSPPAK RNGFKVLLVE DNQAEAELIE ELLLETNVSR AEPQRLSVSC TDRLSKAQQL
LVCEHFDVIL LDLSLPDSQD LNTIVKIQEY SLNTPIVVLT ARNDEELAVQ SIQAGAQDYL
VKRKIDSEVL IRSLRYAVER QHNQEALRKS EEKYRSVVEN SLVGIAILAP PISPSAPEKY
EWLEVNDALC DLLGYDRQDF LHENWERWSF PEDLQASLEQ LNKILAGESE GYVLDQRWRR
KDGNIVYTRV YLRCMRARDG AIDHLIKVVL DVSDSYRYEA QLKASEEFLN HTINSIPDPI
FVKDEQHRWI VLNDAFCNLI GKRRSELIGK SGYDFLPPAQ AAFFWEQDEQ VLQRSLSQET
EEIFTDGGKE RIISTKKTVF NNADSRKMLV GTMRDVSEYK HQQIALQESE ARFQVMTDNV
PGMIYQYRLY VDGKTSFTYV SSGSWQIYNL KPEEIEENAT LAFATVHPDD ISDLQRSIAT
SAATQQAWQH QWRQVMGDRV KWLQGASKPE MQANGDIVWD GLVMDVTELK QTQQDRDRFF
NLSLDLLCIA GFDGYFKRLN PAWSNVLGYS SDEILAKPLI ELVHPEDLEI TVAELEKLKK
SYPVISLENR YLCQDGTYKW LSWTASPFAE EGLIYAVARD VTFSKQAEAE LRKSEATNRA
LLNAIPDMIF RCRADGTFVD FKPAKNFENI LPQKALIGKK AQDILPAAFA EKILSGHQQA
IATGEIQVVE YQMPVNDELY DFEARIVFCT DDEIIAIVRD ITNRKRFESK LHRQAAAMAA
ASEGIAIIDT DGLLIYCNAA RLKIYGYDSL EEVLGKSWKV FYEGAELQRF EQEFVPVLVQ
EGSYMTEAVG CRRDGSKVPL DVSLTMLADG EIICVVRDIS QRKQAEAALR ESQRFIQQIA
GASPNILYVC DLIEKKNIYG NASIYHILGY TVEEIQAMEP WMMSTLIHPE DSIKMPDYLQ
QVETGSEGDI FEIEYRIRHK DGSWRWMVSR DTVFAKTADG KLKQILGTAT DITESKQAED
EIKLLLAATQ AISQSADFYS ALPDILRLLC NAIGWNFAEA WIPTANGTFL EHSETWYASD
RDLDRFGRES KKIRFAAGVA VPGRIWSTRN VEWIEDISLA KNHLFARAQM AASVGLKGCF
GVPIHANSEV LAVLVFCKRE RSTMEPRIVE LVKAVATQLG DHIQRKQAEE ELRKSEERWQ
LVLKGNQDGI WDLNLQTNEA FRSARWQEII GYTDGEIDST NSAWIDRIHP DDRSRVQAAI
QGYLDRQTPN YAAEYRLQCK DGSYKWVLAR AQAVWDEAGN PLRMVGSMTD ISDRKAAELA
LQQVTQAVES TSDAIAIADL KGRSIYHNQA FIQRYGYTVE ELNDLGDMAA LYVRHKNYKQ
IYKSLRQGRS WCGEVSLQTK SGEAVTALVR ADSIQDINGN YIGLIAVITD ITKRKESELI
LRQKLKREQL AVAMLERIRS SLNLEEILTK SVEEVRHFLQ VDRTVIYQFN PDWSGFIAVE
SVAENCRPIV GMEIYDPCFG AAYVSLYQDG RIRAIEDVYN AGLADCHLAL LTRLDVIANI
VVPILQGENL WGLLIAHHCT GPRPWQQLEG ECLKQLGVQL AIAIQQSMLF EQAQTEIADR
KLAEAALQLA KEAAESANRA KSDFLANMSH ELRTPLNGIL GYIQLLKADK NFTADQQESL
NNINQCGNHL LMLINDVLDL SKIEASKMDL SLTNVNFSSF VKSIIDLFQM RSAQKGIAFN
YEQVSALPDG ILADEKRLRQ VLINLLSNAV KFTNSGSVTF KVGYAENFAD NSPQTNCENS
SLTAEIATQT LNLTANLDAP LLSLPPLGTT EAREVITAAN TCDRPPTPKI RFQIEDTGIG
IGQNKLEEIF LPFHQVGDHN NFVEGTGLGL SISQKLVKMM GSQIRVQSTS GKGSIFWVDL
DLPAVAHCSE LPSRPEKRRL VGFTGPQRKV LIVDDHEVNR AMLHRLLFHL GFEIAEATDG
EDCLHKAQEF LPDIILMDLL MPVMNGWEAT RRLRQLPELK DTVILALSAN VYETTKQESI
LAGCDNFLTK PIQTNELLEL LRLHLRLEWV YEERSQTKKR REPTAKASSE IAAADSRMVS
PASESVLALL RLAAMGDIEA ILEETAKLEH SDPTLVPFVH HLRQLAKGFQ LKQIRDFLKQ
HLS
//
