ID K9WV08_9NOST Unreviewed; 610 AA.
AC K9WV08;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Subtilisin-like serine protease {ECO:0000313|EMBL:AFZ23601.1};
GN ORFNames=Cylst_1310 {ECO:0000313|EMBL:AFZ23601.1};
OS Cylindrospermum stagnale PCC 7417.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
OC Cylindrospermum.
OX NCBI_TaxID=56107 {ECO:0000313|EMBL:AFZ23601.1, ECO:0000313|Proteomes:UP000010475};
RN [1] {ECO:0000313|EMBL:AFZ23601.1, ECO:0000313|Proteomes:UP000010475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7417 {ECO:0000313|EMBL:AFZ23601.1,
RC ECO:0000313|Proteomes:UP000010475};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Chen A., Kyrpides N.,
RA Mavromatis K., Markowitz V., Szeto E., Ivanova N., Pagani I., Pati A.,
RA Goodwin L., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T., Kerfeld C.A.;
RT "Finished chromosome of genome of Cylindrospermum stagnale PCC 7417.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; CP003642; AFZ23601.1; -; Genomic_DNA.
DR AlphaFoldDB; K9WV08; -.
DR STRING; 56107.Cylst_1310; -.
DR KEGG; csg:Cylst_1310; -.
DR PATRIC; fig|56107.3.peg.1487; -.
DR eggNOG; COG1404; Bacteria.
DR HOGENOM; CLU_011263_15_4_3; -.
DR Proteomes; UP000010475; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07484; Peptidases_S8_Thermitase_like; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR045986; DUF5942.
DR InterPro; IPR017295; Pept_S8A_subtilisin_cyanobac-1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034084; Thermitase-like_dom.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF19366; DUF5942; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PIRSF; PIRSF037851; Subtilisin_cyano; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000010475};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 442..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..500
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 583..603
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 157..404
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 420..609
FT /note="DUF5942"
FT /evidence="ECO:0000259|Pfam:PF19366"
FT ACT_SITE 166
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 199
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 361
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 610 AA; 64889 MW; F5A67B45EC110E8E CRC64;
MCLFVIGLGA SVFGFLNFQG LAAKGEFETI LLDFREDIPA AVVQQDLQAI AKLYNVTPQL
DNKFSASDNV YIIKGDRDRL KKLKASTFAK ATEIIEPNYI YSKIPQPGEA KWLGEFLTEQ
DDQEVNPSLT GPNDQYYSKQ WNLHKIGVEG AWTLTKGSGI TVAVIDTGIT KVRDLSETKF
VKGYDFVNDR EEATDDNGHG THVAGTVAQA TNNKYGVAGI AYEANLMPLK VLSANGGGTV
ADIAEAIKFA ADKGADVINM SLGGGGESQL MKQAIEYAYK KGVVIIAAAG NESTNGSSYP
ARYPHVIGVS AFGPDGEKAP YSNFGAGVDI SAPGGSEGGA ILQETITENG EAAFLGLQGT
SMASPHVAGV AALIKAAGIK EPDEILKVLK QSARVIQDDG LNYYGAGQLN AEAAVKLATQ
GQISFPDFFR WLRDNGYLNP GFWIDGGAIA LLPKILMVLG SYLLAWFLRV YFPFAWSWSL
SSGLIAGSSG LFFLKGIYIF DLPQWPLRVL GSSIPELGNA LQGTDALNPL FASVLIPIIL
TALLLGHPSG KWFAIGSTLG IAACLTVSAF YDPAVWGLGS SNLARIFLIA NAILCYGLAR
LALPNEGKTA
//
