ID K9XHW4_9CHRO Unreviewed; 492 AA.
AC K9XHW4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN ORFNames=Glo7428_3198 {ECO:0000313|EMBL:AFZ31684.1};
OS Gloeocapsa sp. PCC 7428.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Chroococcaceae; Gloeocapsa.
OX NCBI_TaxID=1173026 {ECO:0000313|EMBL:AFZ31684.1, ECO:0000313|Proteomes:UP000010476};
RN [1] {ECO:0000313|EMBL:AFZ31684.1, ECO:0000313|Proteomes:UP000010476}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7428 {ECO:0000313|EMBL:AFZ31684.1,
RC ECO:0000313|Proteomes:UP000010476};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished chromosome of genome of Gloeocapsa sp. PCC 7428.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003646; AFZ31684.1; -; Genomic_DNA.
DR RefSeq; WP_015189553.1; NC_019745.1.
DR AlphaFoldDB; K9XHW4; -.
DR STRING; 1173026.Glo7428_3198; -.
DR KEGG; glp:Glo7428_3198; -.
DR PATRIC; fig|1173026.3.peg.3394; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_1_10_3; -.
DR OrthoDB; 548310at2; -.
DR Proteomes; UP000010476; Chromosome.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:UniProtKB-EC.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF4; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AFZ31684.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010476}.
FT DOMAIN 15..480
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 492 AA; 53078 MW; 8341F34452B99088 CRC64;
MSCTTVLQNY INGEWCDSSA TAYLDVTNPA TAEILAKVPL GTATDVDQAA TAAATAFNTW
RRTPAGERVQ YLFKLKTLLE ENFADLAATI TQECGKTLAE SKGELQRAIE NVEVACGIPI
LIQGYNSEDI AKGIDEILIR QPVGVAAVIA PFNFPGMIPF WFMPYAIACG NTYIIKPSEK
VPLTMQKVMD LLAQTGIPKG VVNLVNGAKE VVDAILDHPA IRAISFVGST PVARYVYSRA
TANGKRAQCQ GGAKNPVIVL PDADMEMTTR IVADSAFGCA GQRCLAASLA ITVGKARQTF
TDAIADAAST RVVGYGLDDK VQMGPVITAE SQARIEQLIQ QGIAEGATPL VDGRQAKIAD
YPQGYFIRPT LLQNIEPTSK IAQTEVFGPV LGLIHLDTVD EAIAFVNRGE YGNMACLFTS
SGAAARKFRY EAEVGNIGIN IGVAAPMAFF PFSGWKESFF GDLHGQGHHA IEFFTQTKVV
VERWFQDWSR QF
//
