ID K9XP88_9CHRO Unreviewed; 446 AA.
AC K9XP88;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=MscS Mechanosensitive ion channel {ECO:0000313|EMBL:AFZ33482.1};
GN ORFNames=Glo7428_5095 {ECO:0000313|EMBL:AFZ33482.1};
OS Gloeocapsa sp. PCC 7428.
OG Plasmid pGLO7428.02 {ECO:0000313|EMBL:AFZ33482.1,
OG ECO:0000313|Proteomes:UP000010476}.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Chroococcaceae; Gloeocapsa.
OX NCBI_TaxID=1173026 {ECO:0000313|EMBL:AFZ33482.1, ECO:0000313|Proteomes:UP000010476};
RN [1] {ECO:0000313|EMBL:AFZ33482.1, ECO:0000313|Proteomes:UP000010476}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7428 {ECO:0000313|EMBL:AFZ33482.1,
RC ECO:0000313|Proteomes:UP000010476};
RC PLASMID=Plasmid pGLO7428.02 {ECO:0000313|Proteomes:UP000010476};
RG US DOE Joint Genome Institute;
RA Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Davenport K.,
RA Daligault H., Erkkila T., Gu W., Munk A.C.C., Teshima H., Xu Y., Chain P.,
RA Chen A., Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L., Peters L.,
RA Pitluck S., Woyke T., Kerfeld C.;
RT "Finished plasmid 2 of genome of Gloeocapsa sp. PCC 7428.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP003648; AFZ33482.1; -; Genomic_DNA.
DR RefSeq; WP_015328581.1; NC_020051.1.
DR AlphaFoldDB; K9XP88; -.
DR KEGG; glp:Glo7428_5095; -.
DR PATRIC; fig|1173026.3.peg.5374; -.
DR HOGENOM; CLU_037945_7_0_3; -.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000010476; Plasmid pGLO7428.02.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR045275; MscS_archaea/bacteria_type.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30221; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR PANTHER; PTHR30221:SF1; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:AFZ33482.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010476};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..446
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003937931"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 209..249
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 250..315
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 329..406
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 446 AA; 49067 MW; D9B011FF6DDEF7CF CRC64;
MNASAKRLLL RSVATVLVIL LFLPSAVAQA EQVTVRLDGQ AVFRVGEVGK LDATLRVRQI
ERRMNRLLEN PEAIAPPRIE PTNANNTDRV IMIAGVPVVT VTETDAQDNL TTVSVLATQW
SQAIDTALKR ASERRLSPGG RFIAEVQASI ETAFGRLIES AIVIIPRALA ALLVIGLFWA
IATFVRWLMR IIFRRIVEDL TIENLIKQVA YYAVWILGFI VALDAFGFDP QAVATGLGLT
SLALGFALKD ILSNFISGLL ILVLRPFELG DQIIVGETEG KVERIDLRAT QLRTYDGRVV
LVPNAEVFTS RIINNTAAPI RRGSVALFIG YDSDLQKAIG VIQKAAQSTN GVLEEPAPSV
RVQELGQDDI IIEARFWTDS CRSDFVATSS QVRQAIVAAL KEAEIGLPDP DVRILVPRHS
ERWRSALAWK PSSIKPNRMD RNKPSP
//
