ID K9XS03_STAC7 Unreviewed; 617 AA.
AC K9XS03;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Penicillin-binding protein transpeptidase {ECO:0000313|EMBL:AFZ35385.1};
GN OrderedLocusNames=Sta7437_1827 {ECO:0000313|EMBL:AFZ35385.1};
OS Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Pleurocapsales; Dermocarpellaceae;
OC Stanieria.
OX NCBI_TaxID=111780 {ECO:0000313|EMBL:AFZ35385.1, ECO:0000313|Proteomes:UP000010473};
RN [1] {ECO:0000313|Proteomes:UP000010473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29371 / PCC 7437 {ECO:0000313|Proteomes:UP000010473};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
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DR EMBL; CP003653; AFZ35385.1; -; Genomic_DNA.
DR RefSeq; WP_015193056.1; NC_019748.1.
DR AlphaFoldDB; K9XS03; -.
DR STRING; 111780.Sta7437_1827; -.
DR KEGG; scs:Sta7437_1827; -.
DR PATRIC; fig|111780.3.peg.1909; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_2_3; -.
DR OrthoDB; 9770103at2; -.
DR Proteomes; UP000010473; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010473};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 91..211
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 290..605
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 617 AA; 69347 MW; 5485381976CB7DBF CRC64;
MTKSKIKSIP QQPKRASQVS SVKSKRKFQP IRLLLVWLVL VSAALGLTVR LFYLQILNPT
IVNEQAPAFK GKTLKQIAND QQHTLLRFYN PRRQIVDRQQ NVLATDRITY DLYAHPSLFT
VYSKDISPEQ VAQEIAPILP NYTTEKLVQI FNQRKTGIKL ASDLPESVKE KISKLKIDGL
DLQKRYSRFY PYEEMVAEVV GYMNRDRLPL PQAGIEYTQQ QLLQRPEITK SVKRSFIGDR
SIFYVGDLNP QEELLKFDDL RLQLTLDLKI QQAARNALKQ QMLKYKAKRG TVIVMDVRDG
AIAALVSEPT YNPNLYYEYN VELFKNWAIT DLYEPGSTFK PINVAIALDA GVITPNDTFK
DTGKIKVDGW VIRNHDYEDD GARGILTIPQ ILQHSSNVGM IQMMNRLNRE DYYHHLLALG
IEDKLALDIP GYTPGHLKNQ IEFKVKAIEA ATTSFGQGFS LTPLKLIQLH CAIANGGNLV
TPHFVRGLSD VKGYLHWQPT YPSQQVFKPE TTKAVLAMME SVVREKEGSG YVASLPGYRI
AGKTGTAQKA VNEGGYDKKA KITSFVAMFP VEAPRYAILA VVDEPKGAYT FGSTVAAPIV
KSVMEAIIAI EGIPPAQ
//
