ID K9Y7K6_HALP7 Unreviewed; 602 AA.
AC K9Y7K6;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=GTP-binding protein LepA {ECO:0000313|EMBL:AFZ42789.1};
GN OrderedLocusNames=PCC7418_0560 {ECO:0000313|EMBL:AFZ42789.1};
OS Halothece sp. (strain PCC 7418) (Synechococcus sp. (strain PCC 7418)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Halothecacae; Halothece cluster; Halothece.
OX NCBI_TaxID=65093 {ECO:0000313|EMBL:AFZ42789.1, ECO:0000313|Proteomes:UP000010481};
RN [1] {ECO:0000313|Proteomes:UP000010481}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7418 {ECO:0000313|Proteomes:UP000010481};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. LepA subfamily.
CC {ECO:0000256|ARBA:ARBA00005454}.
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DR EMBL; CP003945; AFZ42789.1; -; Genomic_DNA.
DR RefSeq; WP_015224667.1; NC_019779.1.
DR AlphaFoldDB; K9Y7K6; -.
DR STRING; 65093.PCC7418_0560; -.
DR KEGG; hao:PCC7418_0560; -.
DR PATRIC; fig|65093.3.peg.591; -.
DR eggNOG; COG0481; Bacteria.
DR HOGENOM; CLU_009995_3_3_3; -.
DR OrthoDB; 580826at2; -.
DR Proteomes; UP000010481; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd03699; EF4_II; 1.
DR CDD; cd16260; EF4_III; 1.
DR CDD; cd01890; LepA; 1.
DR CDD; cd03709; lepA_C; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.2570; Elongation factor 4, C-terminal domain; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR HAMAP; MF_03138; GUFP; 1.
DR HAMAP; MF_00071; LepA; 1.
DR InterPro; IPR006297; EF-4.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027518; GUFP.
DR InterPro; IPR038363; LepA_C_sf.
DR InterPro; IPR013842; LepA_CTD.
DR InterPro; IPR035654; LepA_IV.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR NCBIfam; TIGR01393; lepA; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43512:SF4; TRANSLATION FACTOR GUF1 HOMOLOG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43512; TRANSLATION FACTOR GUF1-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF06421; LepA_C; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000010481}.
FT DOMAIN 7..189
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 602 AA; 67488 MW; 41FC6AD2EB3C257A CRC64;
MTNVPVSRFR NFSIIAHIDH GKSTLADQLL RWTDTVKERE MKEQFLDNMD LERERGITIK
LQAARMNYTA KDGETYVLNL IDTPGHVDFS YEVSRSLVAC EGALLVVDAS QGVEAQTLAN
IYLALEEDLE IIPVLNKIDL PGAEPERVLE EIEEAIGLDC SNAIMASAKM GKGIDEILEA
IVHLIPPPQD TTEDPLRALI FDSYYDLYRG VIVYFRVVDG TVKVGDKIRL MASKKEYEID
EIGILSPTKV PVEQLHAGEV GYLAASIKAV EDARVGDTIT LANQPASSPL PGYKEAKPMV
FCGLFPTSTD DYADLRDALD KLKLNDSALS YEPETSSAMG FGFRCGFLGL LHMEIVQERL
EREYDLDLVV TAPSVIYRVM LNDGEIIEVD NPSLLPSPQE REMVEEPYIH LEIITPEEYV
GALMELCQAR RGDFKDMKYF TPTRTTLIYE LPLAEVVTDF FDQMKSRSRG YASMEYNFLG
YRANELVKLD IMVNNESVDS LAMIVHRDKA YSVGKSLVEK LKELIPRQQF KIPVQAGIGT
RIIASAHIPP LRKDVLAKCY GGDISRKKKL LQKQAKGKKR MKAIGTVDVP QEAFMAVLKL
EQ
//
