ID K9Y9J2_HALP7 Unreviewed; 426 AA.
AC K9Y9J2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Sodium/proton antiporter, CPA1 family {ECO:0000313|EMBL:AFZ43085.1};
GN OrderedLocusNames=PCC7418_0870 {ECO:0000313|EMBL:AFZ43085.1};
OS Halothece sp. (strain PCC 7418) (Synechococcus sp. (strain PCC 7418)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Halothecacae; Halothece cluster; Halothece.
OX NCBI_TaxID=65093 {ECO:0000313|EMBL:AFZ43085.1, ECO:0000313|Proteomes:UP000010481};
RN [1] {ECO:0000313|Proteomes:UP000010481}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7418 {ECO:0000313|Proteomes:UP000010481};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003945; AFZ43085.1; -; Genomic_DNA.
DR RefSeq; WP_015224963.1; NC_019779.1.
DR AlphaFoldDB; K9Y9J2; -.
DR STRING; 65093.PCC7418_0870; -.
DR KEGG; hao:PCC7418_0870; -.
DR PATRIC; fig|65093.3.peg.927; -.
DR eggNOG; COG0025; Bacteria.
DR HOGENOM; CLU_008635_6_2_3; -.
DR OrthoDB; 9810860at2; -.
DR Proteomes; UP000010481; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR InterPro; IPR006153; Cation/H_exchanger.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR PANTHER; PTHR32507:SF0; NA(+)_H(+) ANTIPORTER 2-RELATED; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010481};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..389
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 426 AA; 46516 MW; DDC12AAF92D18774 CRC64;
MTIETFAIIA FFILGFGLIS GYLEKTVITP PMVFVTFGLL LSTQGLGMIN LNPDSEGIRL
IAELTLILVL FTDASRINLQ RLEREFTLPL RLLGIALPVI IALGTLLGYL IFPEQFTLWE
AAILATILAP TDAALGQAVV NSRQVPVCIR QAINVESGLN DGICLPILFI FFSLAGMDEK
GEGLGFWVLF TTEQLLLGPF IGVAIGYIGG WLVTESVDRK LINHAFENLS VIGISVLAYA
SAELVGGNGL IAAFCAGLTV GNTATPICQC LYDFGEAEGQ LLILIIFLLF GATMVFPTVD
DLNWQIIIYA VTSLTIIRLL GVAVSVIGLR LQWTTTLFLG WFGPRGVASV LYGLLLLEQQ
AIVERELIFS TMVTTVLCSV FAHGLTAFPG AHWYGMQMEQ ASDDLPEMKI VHDFPVRLPW
LDMRRH
//
