ID   K9Z178_CYAAP            Unreviewed;       727 AA.
AC   K9Z178;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Lytic transglycosylase catalytic {ECO:0000313|EMBL:AFZ52919.1};
GN   OrderedLocusNames=Cyan10605_0786 {ECO:0000313|EMBL:AFZ52919.1};
OS   Cyanobacterium aponinum (strain PCC 10605).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Geminocystaceae; Cyanobacterium.
OX   NCBI_TaxID=755178 {ECO:0000313|EMBL:AFZ52919.1, ECO:0000313|Proteomes:UP000010480};
RN   [1] {ECO:0000313|Proteomes:UP000010480}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 10605 {ECO:0000313|Proteomes:UP000010480};
RX   PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA   Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA   Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA   Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA   Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT   "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT   genome sequencing.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC   -!- SIMILARITY: Belongs to the transglycosylase Slt family.
CC       {ECO:0000256|ARBA:ARBA00007734}.
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DR   EMBL; CP003947; AFZ52919.1; -; Genomic_DNA.
DR   RefSeq; WP_015218650.1; NC_019776.1.
DR   AlphaFoldDB; K9Z178; -.
DR   STRING; 755178.Cyan10605_0786; -.
DR   KEGG; can:Cyan10605_0786; -.
DR   PATRIC; fig|755178.3.peg.827; -.
DR   eggNOG; COG0741; Bacteria.
DR   eggNOG; COG1729; Bacteria.
DR   eggNOG; COG4105; Bacteria.
DR   HOGENOM; CLU_013746_0_0_3; -.
DR   OrthoDB; 9815002at2; -.
DR   Proteomes; UP000010480; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   CDD; cd13401; Slt70-like; 1.
DR   Gene3D; 1.10.530.10; -; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR008939; Lytic_TGlycosylase_superhlx_U.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR008258; Transglycosylase_SLT_dom_1.
DR   PANTHER; PTHR37423:SF2; SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE; 1.
DR   PANTHER; PTHR37423; SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED; 1.
DR   Pfam; PF01464; SLT; 1.
DR   Pfam; PF13174; TPR_6; 3.
DR   SUPFAM; SSF48435; Bacterial muramidases; 1.
DR   SUPFAM; SSF53955; Lysozyme-like; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010480};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          577..689
FT                   /note="Transglycosylase SLT"
FT                   /evidence="ECO:0000259|Pfam:PF01464"
SQ   SEQUENCE   727 AA;  83589 MW;  AF4FCBE1A46D4DEB CRC64;
     MKTDKSKKNQ VIIQIVVILA VCVAGATFFT PKLLEILNSV LISPFEKKPE YRLDAPSEVL
     PLANLTPSER KASLEVIANK DTSSLDVNRA KYLLAVDALR NDFDGAKALQ YLENLDRTYP
     ILAPYVLLLQ GRAYELNNNT EKAQKIWQDV INKYPDELVS AQAYYKLGNY DPKFFQEAIN
     RFPQHPRTHD IAIKLLEENP QQKELLLLLA EYDIVPENKA RVDRLVKEYS QELEPQQWDI
     VGNYYWETGN YNLVSSAYEK GTSTPQNLYR IARSYQVSDK EKEAKTAYFK LVETYPDAPE
     TGLAWRRLAT ISGGEEALSF LNRVDEKYPD EVVIALREKA TLLTQLGRYQ EATNVRDTIL
     QKYPQSEEAA DYRWQIAKDF ADSGDYVSAW QWAQQISVNN PDSGVAPKAG FWIGKWAEKL
     GQNQEATKAY EYVLQNHPHS YYAWRSAVRL GKDVGDFNNL RSLPLQVEIP QQRPIPPAGS
     NQFKELFLLG EDQDAIDLFT AEIGKKSSST DTLPVVTVSE QFVQGLLKQN QGKYLESINL
     IWNLKNRDNP EDIGEWQILR RSPEYWYALF PFPYEELIVK WSKKRNLNPF LVVSLMRQES
     RFEKDIKSPV GATGLMQIMP ETGAWIAPQI NIKEYSLTDP EDNIKMGTWY LNYTHDTYND
     NSMLAIASYN AGPGNVSNWI SRYSLADIDE FVENIPFPET KNYVETVFGN YWNYVELYDP
     KIEEKLN
//