ID   K9Z2K8_CYAAP            Unreviewed;       826 AA.
AC   K9Z2K8;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:AFZ52613.1};
GN   OrderedLocusNames=Cyan10605_0471 {ECO:0000313|EMBL:AFZ52613.1};
OS   Cyanobacterium aponinum (strain PCC 10605).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Geminocystaceae; Cyanobacterium.
OX   NCBI_TaxID=755178 {ECO:0000313|EMBL:AFZ52613.1, ECO:0000313|Proteomes:UP000010480};
RN   [1] {ECO:0000313|Proteomes:UP000010480}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 10605 {ECO:0000313|Proteomes:UP000010480};
RX   PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA   Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA   Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA   Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA   Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT   "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT   genome sequencing.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
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DR   EMBL; CP003947; AFZ52613.1; -; Genomic_DNA.
DR   RefSeq; WP_015218344.1; NC_019776.1.
DR   AlphaFoldDB; K9Z2K8; -.
DR   STRING; 755178.Cyan10605_0471; -.
DR   KEGG; can:Cyan10605_0471; -.
DR   PATRIC; fig|755178.3.peg.499; -.
DR   eggNOG; COG1716; Bacteria.
DR   eggNOG; COG2199; Bacteria.
DR   eggNOG; COG2200; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 415644at2; -.
DR   Proteomes; UP000010480; Chromosome.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010480}.
FT   DOMAIN          29..89
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   DOMAIN          267..310
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          423..562
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          566..820
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   826 AA;  94650 MW;  247AE460912F16D8 CRC64;
     MSEAQEFRHI LVIEDRKGRR IVFLEESNYT IGRDSHNPII LYDYQVSRTH ATLIRKMDEE
     GENFSYRLID GDLQGKKSTN GVFVNGHSTI SHELKHGDSI RFGTDAKANY YIVPSDSSID
     LFNPENLDRI SASRVTLTNQ SSETMISKEE NSSNPEDQQE LIRLASFPEL SPNPIIELDW
     EGNITYINPA ASIKFETIHE DKLDHPILSG LLTEYNNRQG NLFLREVKIG SEVFEQYVHY
     LSEKKLVRSY IYDFTQRKQT EAQLKDSQSR YLAILKHISE GVFLAYASNR RIIEINDGFS
     KLLGYSSEDL SNLTLYNIVA SDLASFNKDL TQVQETKQDL LEEYLYRRPD GTLVNLESSV
     SLITYQNKEI FCFVLRNPNK QVSSTQDYSN YLAFHDALLN IPNQNLFEQQ LEIAIANAQR
     YQYLMGVLFA QIENWQEYQN QHPKDESEKL LKNFTQIFQS CLRTGDLIAR WDEDKFAVLF
     PHIRGPRDPA RITKKISSTL TSYLQEQTAN KQVKLELKLS LLIYPIDGED KSLITKNGLL
     SLEQVKISNP NYGATGFNLT PKGASLLKLE NLIGTAVKEQ QFFLCYQPQT DINTRELTGL
     ETLLRWEHPE LGKITPRHFL RLTEETDFML PLGIWILQTA TMQMQKWTHE NISPLPIGVN
     ISARQFCQPN FLETIIKILE QTGLPAHLLE LEITENCFLH NPDYAYQILN KLSEQKVRLC
     FDGFGSGTSS LVYLQKVPFN TVKISPSIIT QLDNNSQNQS LVQCMSAFCQ GYNSRLVAVG
     VEKLEQMELL RNLGCHQIQG NLLSRPLPSK DITTFLNKGD HQLTNS
//