ID K9Z483_CYAAP Unreviewed; 847 AA.
AC K9Z483;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:AFZ53949.1};
GN OrderedLocusNames=Cyan10605_1847 {ECO:0000313|EMBL:AFZ53949.1};
OS Cyanobacterium aponinum (strain PCC 10605).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Geminocystaceae; Cyanobacterium.
OX NCBI_TaxID=755178 {ECO:0000313|EMBL:AFZ53949.1, ECO:0000313|Proteomes:UP000010480};
RN [1] {ECO:0000313|Proteomes:UP000010480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 10605 {ECO:0000313|Proteomes:UP000010480};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
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DR EMBL; CP003947; AFZ53949.1; -; Genomic_DNA.
DR AlphaFoldDB; K9Z483; -.
DR STRING; 755178.Cyan10605_1847; -.
DR KEGG; can:Cyan10605_1847; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_46_3; -.
DR OrthoDB; 415447at2; -.
DR Proteomes; UP000010480; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010480};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 286..352
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 361..411
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 444..582
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 591..847
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 847 AA; 97656 MW; 986D072E4F3DD269 CRC64;
MKKFISLRTK ILISYTVVFT LFFLCLYWWS YRSSMKRSLE RLTNNLKQVA IASSQQIDTE
ELKQLFQEGK ANEEGSSDDP RYKSQLQWME KINQLHPNIF LFTFTHPNIS QLSPTDKTEI
IYLVDVWRGK NPQKSVDFLE SAPATSYHLQ TLAEGATVYR NFYKDKWGSW ITYYAPIKDS
SGQIIAGIGA DMQTEEINEI QKDIRERFLS FFVISYPIFF CSIIGLSHFL TTRLGKLQKY
AQAVGEGNYQ PDIDISDTNF MFSVFRDERM VLSKALREMA GKIKQREDLL NGIFNQVAVG
IAIHDVDYRL EIVNNTLCKL LDYSENELRQ QSGYFFIHPE DTVSTQEYLR EICFSTNLNP
TSVEKRIITK KGEVKWLEIT TTIIGEREKQ CFVTIFQDVT KRRFMETKLI EAANTDFLTK
LPNRAYFMAT LENLLQEAKN TPHQLFALLL VDLDNFKTIN DSLGHLAGDK FLIDIAYSLR
RCLSSSHMVA RLGGDEFAIL LDSITKVEDA IAVAEKIQVE ISSPFYIHNQ EFFTTCSIGI
VLSHNQTTNS PYLRAEDLFR DADIAMYQVK NKGKGDYQVF GREMYDDFIR RLQLQNDLRK
SIEKDNLIIY YQPIIDLKTG KITSIESLVR WQHPELGFLN PNKFLPIAEQ SGLMISLGKL
VLNKACNQLK QWQEANLIPE NVCINVNVSE QQFEQGNILQ QIKDVLNKTQ ISPHNLRIEI
TESIIAHQIQ NITKILSEIK KLGVKIAIDD FGTGYSSLAR LRNFPLNQIK IDKAFVKPLN
THPKNIKFLQ GIITLCHNLE LNVVCEGIET ETQLEILQKL NCNYGQGYLF SKPLSQEEFS
LWIMNQI
//
