ID K9Z8K1_CYAAP Unreviewed; 567 AA.
AC K9Z8K1;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN OrderedLocusNames=Cyan10605_3491 {ECO:0000313|EMBL:AFZ55526.1};
OS Cyanobacterium aponinum (strain PCC 10605).
OG Plasmid pCYAN10605.01 {ECO:0000313|EMBL:AFZ55526.1,
OG ECO:0000313|Proteomes:UP000010480}.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Geminocystaceae; Cyanobacterium.
OX NCBI_TaxID=755178 {ECO:0000313|EMBL:AFZ55526.1, ECO:0000313|Proteomes:UP000010480};
RN [1] {ECO:0000313|Proteomes:UP000010480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 10605 {ECO:0000313|Proteomes:UP000010480};
RC PLASMID=Plasmid pCYAN10605.01 {ECO:0000313|Proteomes:UP000010480};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; CP003948; AFZ55526.1; -; Genomic_DNA.
DR RefSeq; WP_015221244.1; NC_019777.1.
DR AlphaFoldDB; K9Z8K1; -.
DR KEGG; can:Cyan10605_3491; -.
DR eggNOG; COG0210; Bacteria.
DR HOGENOM; CLU_034823_0_0_3; -.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000010480; Plasmid pCYAN10605.01.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Plasmid {ECO:0000313|EMBL:AFZ55526.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010480}.
FT DOMAIN 3..323
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 24..31
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 567 AA; 65004 MW; 6376192DEDF299C3 CRC64;
MKWSNYQQKI FESIAPSHNM LIEAVAGSGK TTTIIEIVKL LKKKGLVSRN NGNGLVCAFN
KHIEVTLSQK IKGTKFVSKT LNAIGHGILV RHSYPRQIKI NTNKYYSICE QVIDYFSPSY
LFELKLKGLV NAEYKGKKNG VIGFERLKAR RKSDYPYVFD EFNDFVQVVN TCRKEYSKHF
LSIEDLQNLM AEYPLEISDY LKKKELHQTI AVEAINKALE YGINSYLNES TIDFSDQLWL
PLTMGLFPIT KYDWIIVDES QDLNLNQARL IKVLGKSSST YIFVGDSKQS IYLFNGAKPD
CMSLIKKYFN CNKYPLSLCY RCPPNHLKLA KEYNPQIEAF KQEDGLIKQL TITEVRDLVK
GCYQTGTEIL LISRLNYIFF DVLCQCAFGD KIKVSLLGKD LAGELVKLAR QILPSRFTDF
SKINQILNGY VEYYSEQMDS SKADYCKCLM STWRYIEPST INDLENVLNS VIISEGVIKF
GSIHRAKGTE SDHVVILGDN LLPYIPTNRE LTSKETQQEE NLTYVAFTRS KKNLYLVPYT
NGNDEHREVE LNLNDDNIFG ADINYGF
//
