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Database: UniProt
Entry: KDGT_ECOLI
LinkDB: KDGT_ECOLI
Original site: KDGT_ECOLI 
ID   KDGT_ECOLI              Reviewed;         327 AA.
AC   P0A712; P32172; Q2M8K6;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   28-MAR-2018, entry version 91.
DE   RecName: Full=2-keto-3-deoxygluconate permease;
DE            Short=KDG permease;
GN   Name=kdgT; OrderedLocusNames=b3909, JW5560;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=8346018; DOI=10.1093/nar/21.15.3391;
RA   Plunkett G. III, Burland V., Daniels D.L., Blattner F.R.;
RT   "Analysis of the Escherichia coli genome. III. DNA sequence of the
RT   region from 87.2 to 89.2 minutes.";
RL   Nucleic Acids Res. 21:3391-3398(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
RA   Mau B., Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains
RT   MG1655 and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- FUNCTION: The 2-keto-3-deoxygluconate permease transports the
CC       degraded pectin products into the bacterial cell, where they serve
CC       as carbon and energy sources. This is a hydrogen coupled transport
CC       system.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the KdgT transporter family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB03042.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
DR   EMBL; L19201; AAB03042.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC76891.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77400.1; -; Genomic_DNA.
DR   PIR; S40853; S40853.
DR   RefSeq; NP_418345.2; NC_000913.3.
DR   RefSeq; WP_001166063.1; NZ_LN832404.1.
DR   ProteinModelPortal; P0A712; -.
DR   BioGrid; 4259555; 9.
DR   STRING; 316385.ECDH10B_4099; -.
DR   TCDB; 2.A.10.1.2; the 2-keto-3-deoxygluconate transporter (kdgt) family.
DR   PaxDb; P0A712; -.
DR   PRIDE; P0A712; -.
DR   EnsemblBacteria; AAC76891; AAC76891; b3909.
DR   EnsemblBacteria; BAE77400; BAE77400; BAE77400.
DR   GeneID; 948407; -.
DR   KEGG; ecj:JW5560; -.
DR   KEGG; eco:b3909; -.
DR   PATRIC; fig|1411691.4.peg.2795; -.
DR   EchoBASE; EB1815; -.
DR   EcoGene; EG11869; kdgT.
DR   eggNOG; ENOG4105CAX; Bacteria.
DR   eggNOG; ENOG410XNUJ; LUCA.
DR   HOGENOM; HOG000221851; -.
DR   InParanoid; P0A712; -.
DR   KO; K02526; -.
DR   OMA; ESGPFMT; -.
DR   BioCyc; EcoCyc:KDGT-MONOMER; -.
DR   BioCyc; MetaCyc:KDGT-MONOMER; -.
DR   PRO; PR:P0A712; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IDA:EcoCyc.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0015649; F:2-keto-3-deoxygluconate:proton symporter activity; IDA:EcoCyc.
DR   GO; GO:0035429; P:gluconate transmembrane transport; IDA:EcoCyc.
DR   HAMAP; MF_00070; KdgT; 1.
DR   InterPro; IPR004684; 2keto-3dGluconate_permease.
DR   InterPro; IPR018395; 2keto-3dGluconate_permease_sub.
DR   Pfam; PF03812; KdgT; 1.
DR   ProDom; PD024513; 2keto-3dGluconate_permease; 1.
DR   TIGRFAMs; TIGR00793; kdgT; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Reference proteome; Sugar transport; Symport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN         1    327       2-keto-3-deoxygluconate permease.
FT                                /FTId=PRO_0000209675.
FT   TOPO_DOM      1      9       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM     10     30       Helical. {ECO:0000255}.
FT   TOPO_DOM     31     41       Periplasmic. {ECO:0000255}.
FT   TRANSMEM     42     62       Helical. {ECO:0000255}.
FT   TOPO_DOM     63     72       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM     73     93       Helical. {ECO:0000255}.
FT   TOPO_DOM     94     94       Periplasmic. {ECO:0000255}.
FT   TRANSMEM     95    115       Helical. {ECO:0000255}.
FT   TOPO_DOM    116    138       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    139    159       Helical. {ECO:0000255}.
FT   TOPO_DOM    160    162       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    163    183       Helical. {ECO:0000255}.
FT   TOPO_DOM    184    198       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    199    219       Helical. {ECO:0000255}.
FT   TOPO_DOM    220    223       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    224    244       Helical. {ECO:0000255}.
FT   TOPO_DOM    245    253       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    254    274       Helical. {ECO:0000255}.
FT   TOPO_DOM    275    288       Periplasmic. {ECO:0000255}.
FT   TRANSMEM    289    309       Helical. {ECO:0000255}.
FT   TOPO_DOM    310    327       Cytoplasmic. {ECO:0000255}.
SQ   SEQUENCE   327 AA;  33669 MW;  8F870CB233B35453 CRC64;
     MQIKRSIEKI PGGMMLVPLF LGALCHTFSP GAGKYFGSFT NGMITGTVPI LAVWFFCMGA
     SIKLSATGTV LRKSGTLVVT KIAVAWVVAA IASRIIPEHG VEVGFFAGLS TLALVAAMDM
     TNGGLYASIM QQYGTKEEAG AFVLMSLESG PLMTMIILGT AGIASFEPHV FVGAVLPFLV
     GFALGNLDPE LREFFSKAVQ TLIPFFAFAL GNTIDLTVIA QTGLLGILLG VAVIIVTGIP
     LIIADKLIGG GDGTAGIAAS SSAGAAVATP VLIAEMVPAF KPMAPAATSL VATAVIVTSI
     LVPILTSIWS RKVKARAAKI EILGTVK
//
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