GenomeNet

Database: UniProt
Entry: KI3L3_HUMAN
LinkDB: KI3L3_HUMAN
Original site: KI3L3_HUMAN 
ID   KI3L3_HUMAN             Reviewed;         410 AA.
AC   Q8N743; A9PL62; A9PL64; A9PL65; A9PL66; A9PL67; A9PL68; A9PZV4; A9PZV7;
AC   A9PZV8; A9Q066; A9Q0R5; A9Q242; A9Q250; A9Q251; O95056; Q1X775; Q1X777;
AC   Q1X778; Q1X779; Q1X780; Q1X781; Q1X782; Q1X783; Q7Z7N4; Q8NHI2; Q8NHI3;
AC   Q9UEI4;
DT   26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   24-NOV-2009, sequence version 2.
DT   12-AUG-2020, entry version 157.
DE   RecName: Full=Killer cell immunoglobulin-like receptor 3DL3;
DE   AltName: Full=CD158 antigen-like family member Z;
DE   AltName: Full=Killer cell inhibitory receptor 1;
DE   AltName: CD_antigen=CD158z;
DE   Flags: Precursor;
GN   Name=KIR3DL3; Synonyms=CD158Z, KIR3DL7, KIRC1;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000312|EMBL:CAC40702.1};
RN   [1] {ECO:0000312|EMBL:AAC99763.1}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE KIR3DL3*00101), VARIANTS ILE-168
RP   AND ASN-321, AND POLYMORPHISM.
RX   PubMed=9862332;
RX   DOI=10.1002/(sici)1521-4141(199812)28:12<3959::aid-immu3959>3.0.co;2-2;
RA   Torkar M., Norgate Z., Colonna M., Trowsdale J., Wilson M.J.;
RT   "Isotypic variation of novel immunoglobulin-like transcript/killer cell
RT   inhibitory receptor loci in the leukocyte receptor complex.";
RL   Eur. J. Immunol. 28:3959-3967(1998).
RN   [2] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA] (ALLELE KIR3DL3*00401), VARIANTS HIS-52 AND
RP   TYR-321, POLYMORPHISM, AND REVIEW.
RC   TISSUE=Peripheral blood {ECO:0000312|EMBL:AAK30258.1};
RX   PubMed=11513144; DOI=10.1034/j.1600-065x.2001.1810119.x;
RA   Long E.O., Barber D.F., Burshtyn D.N., Faure M., Peterson M.,
RA   Rajagopalan S., Renard V., Sandusky M., Stebbins C.C., Wagtmann N.,
RA   Watzl C.;
RT   "Inhibition of natural killer cell activation signals by killer cell
RT   immunoglobulin-like receptors (CD158).";
RL   Immunol. Rev. 181:223-233(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA   Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA   Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA   Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA   Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA   Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA   Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA   Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA   Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA   McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA   Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA   Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA   She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA   Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 18-410 (ALLELES KIR3DL3*00101;
RP   KIR3DL3*00202; KIR3DL3*0030101; KIR3DL3*00402; KIR3DL3*005; KIR3DL3*00601;
RP   KIR3DL3*007; KIR3DL3*00801 AND KIR3DL3*00802), AND POLYMORPHISM.
RX   PubMed=16634863; DOI=10.1111/j.1399-0039.2006.00567.x;
RA   Steiner N.K., Hurley C.K.;
RT   "KIR3DL3 allelic diversity: six new alleles exhibit both conservative and
RT   non-conservative substitutions.";
RL   Tissue Antigens 67:277-283(2006).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 18-410 (ALLELES KIR3DL3*00101;
RP   KIR3DL3*00102; KIR3DL3*00103; KIR3DL3*00206; KIR3DL3*00207;
RP   KIR3DL3*0030101; KIR3DL3*00402; KIR3DL3*005; KIR3DL3*00602; KIR3DL3*007;
RP   KIR3DL3*00901; KIR3DL3*00902; KIR3DL3*010; KIR3DL3*01101; KIR3DL3*01102;
RP   KIR3DL3*01302; KIR3DL3*01305; KIR3DL3*01306; KIR3DL3*01307; KIR3DL3*01404;
RP   KIR3DL3*01405; KIR3DL3*01501; KIR3DL3*01601; KIR3DL3*017; KIR3DL3*026;
RP   KIR3DL3*027; KIR3DL3*028; KIR3DL3*029; KIR3DL3*030 AND KIR3DL3*031), AND
RP   POLYMORPHISM.
RX   PubMed=17900289; DOI=10.1111/j.1399-0039.2007.00930.x;
RA   Hou L., Chen M., Steiner N.K., Belle I., Turino C., Ng J., Hurley C.K.;
RT   "Seventeen novel alleles add to the already extensive KIR3DL3 diversity.";
RL   Tissue Antigens 70:449-454(2007).
RN   [6] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 120-316, AND VARIANT THR-290.
RX   PubMed=11960306; DOI=10.1038/sj.gene.6363836;
RA   Norman P.J., Carrington C.V.F., Byng M., Maxwell L.D., Curran M.D.,
RA   Stephens H.A.F., Chandanayingyong D., Verity D.H., Hameed K., Ramdath D.D.,
RA   Vaughan R.W.;
RT   "Natural killer immunoglobulin-like receptor (KIR) locus profiles in
RT   African and South Asian populations.";
RL   Genes Immun. 3:86-95(2002).
CC   -!- FUNCTION: Receptor on natural killer cells. May inhibit the activity of
CC       NK cells thus preventing cell lysis. {ECO:0000303|PubMed:11513144}.
CC   -!- INTERACTION:
CC       Q8N743; Q08AM2: ADAM33; NbExp=3; IntAct=EBI-17272405, EBI-10225815;
CC       Q8N743; Q6RW13-2: AGTRAP; NbExp=3; IntAct=EBI-17272405, EBI-11522760;
CC       Q8N743; P78348: ASIC1; NbExp=3; IntAct=EBI-17272405, EBI-79189;
CC       Q8N743; P01031: C5; NbExp=3; IntAct=EBI-17272405, EBI-8558308;
CC       Q8N743; P19397: CD53; NbExp=3; IntAct=EBI-17272405, EBI-6657396;
CC       Q8N743; Q96DZ9-2: CMTM5; NbExp=3; IntAct=EBI-17272405, EBI-11522780;
CC       Q8N743; Q4LDR2: CTXN3; NbExp=3; IntAct=EBI-17272405, EBI-12019274;
CC       Q8N743; P56851: EDDM3B; NbExp=3; IntAct=EBI-17272405, EBI-10215665;
CC       Q8N743; P54852: EMP3; NbExp=3; IntAct=EBI-17272405, EBI-3907816;
CC       Q8N743; Q96F15: GIMAP5; NbExp=3; IntAct=EBI-17272405, EBI-6166686;
CC       Q8N743; Q8N5M9: JAGN1; NbExp=3; IntAct=EBI-17272405, EBI-10266796;
CC       Q8N743; Q13571: LAPTM5; NbExp=3; IntAct=EBI-17272405, EBI-2865663;
CC       Q8N743; Q9NZG7: NINJ2; NbExp=3; IntAct=EBI-17272405, EBI-10317425;
CC       Q8N743; Q6UX06: OLFM4; NbExp=3; IntAct=EBI-17272405, EBI-2804156;
CC       Q8N743; Q9Y6X1: SERP1; NbExp=3; IntAct=EBI-17272405, EBI-10329948;
CC       Q8N743; P78382: SLC35A1; NbExp=3; IntAct=EBI-17272405, EBI-12870360;
CC       Q8N743; Q96JW4: SLC41A2; NbExp=3; IntAct=EBI-17272405, EBI-10290130;
CC       Q8N743; Q9BZL3: SMIM3; NbExp=3; IntAct=EBI-17272405, EBI-741850;
CC       Q8N743; Q8N2H4: SYS1; NbExp=3; IntAct=EBI-17272405, EBI-13075176;
CC       Q8N743; Q9H2S6-2: TNMD; NbExp=3; IntAct=EBI-17272405, EBI-12003398;
CC       Q8N743; O00526: UPK2; NbExp=3; IntAct=EBI-17272405, EBI-10179682;
CC       Q8N743; O95183: VAMP5; NbExp=3; IntAct=EBI-17272405, EBI-10191195;
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane
CC       protein.
CC   -!- POLYMORPHISM: Various different KIR3DL3 alleles are known:
CC       KIR3DL3*00101, KIR3DL3*00102, KIR3DL3*00103, KIR3DL3*00201,
CC       KIR3DL3*00202, KIR3DL3*00203, KIR3DL3*00204, KIR3DL3*00205,
CC       KIR3DL3*00206, KIR3DL3*00207, KIR3DL3*0030101 KIR3DL3*0030102,
CC       KIR3DL3*00401, KIR3DL3*00402, KIR3DL3*005, KIR3DL3*00601,
CC       KIR3DL3*00602, KIR3DL3*007, KIR3DL3*00801, KIR3DL3*00802,
CC       KIR3DL3*00901, KIR3DL3*00902, KIR3DL3*010, KIR3DL3*01101,
CC       KIR3DL3*01102, KIR3DL3*012, KIR3DL3*01301, KIR3DL3*01302,
CC       KIR3DL3*01303, KIR3DL3*01304, KIR3DL3*01305, KIR3DL3*01306,
CC       KIR3DL3*01307, KIR3DL3*01401, KIR3DL3*01402, KIR3DL3*01403,
CC       KIR3DL3*01404, KIR3DL3*01405, KIR3DL3*015 KIR3DL3*016, KIR3DL3*017,
CC       KIR3DL3*018, KIR3DL3*019, KIR3DL3*020, KIR3DL3*021, KIR3DL3*022,
CC       KIR3DL3*023, KIR3DL3*024, KIR3DL3*025, KIR3DL3*026, KIR3DL3*027,
CC       KIR3DL3*028, KIR3DL3*029, KIR3DL3*030 and KIR3DL3*031. The sequence
CC       shown corresponds to the alleles KIR3DL3*002.
CC       {ECO:0000269|PubMed:11513144, ECO:0000269|PubMed:16634863,
CC       ECO:0000269|PubMed:17900289, ECO:0000269|PubMed:9862332}.
CC   -!- SIMILARITY: Belongs to the immunoglobulin superfamily. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=IPD-KIR Database; Note=KIR Allele Nomenclature;
CC       URL="https://www.ebi.ac.uk/cgi-bin/ipd/kir/view_nomenclature.cgi?kir.3dl3";
DR   EMBL; AF072410; AAC99763.1; -; Genomic_DNA.
DR   EMBL; AF072407; AAC99763.1; JOINED; Genomic_DNA.
DR   EMBL; AF072408; AAC99763.1; JOINED; Genomic_DNA.
DR   EMBL; AF072409; AAC99763.1; JOINED; Genomic_DNA.
DR   EMBL; AF352324; AAK30258.1; -; mRNA.
DR   EMBL; AC006293; AAD03159.1; -; Genomic_DNA.
DR   EMBL; AL133414; CAC40702.1; -; Genomic_DNA.
DR   EMBL; AY987937; ABC03227.1; -; Genomic_DNA.
DR   EMBL; AY987938; ABC03228.1; -; Genomic_DNA.
DR   EMBL; AY987939; ABC03229.1; -; Genomic_DNA.
DR   EMBL; AY987940; ABC03230.1; -; Genomic_DNA.
DR   EMBL; AY987941; ABC03231.1; -; Genomic_DNA.
DR   EMBL; AY987942; ABC03232.1; -; Genomic_DNA.
DR   EMBL; AY987943; ABC03233.1; -; Genomic_DNA.
DR   EMBL; AH015397; ABC03234.1; -; Genomic_DNA.
DR   EMBL; AH015396; ABC03226.1; -; Genomic_DNA.
DR   EMBL; EF153459; ABM98078.1; -; Genomic_DNA.
DR   EMBL; EF153460; ABM98079.1; -; Genomic_DNA.
DR   EMBL; EF153461; ABM98080.1; -; Genomic_DNA.
DR   EMBL; EF153462; ABM98081.1; -; Genomic_DNA.
DR   EMBL; EF153463; ABM98082.1; -; Genomic_DNA.
DR   EMBL; EF153464; ABM98083.1; -; Genomic_DNA.
DR   EMBL; EF153465; ABM98084.1; -; Genomic_DNA.
DR   EMBL; EF153466; ABM98085.1; -; Genomic_DNA.
DR   EMBL; EF153467; ABM98086.1; -; Genomic_DNA.
DR   EMBL; EF165005; ABM98087.1; -; Genomic_DNA.
DR   EMBL; EF165006; ABM98088.1; -; Genomic_DNA.
DR   EMBL; EF165007; ABM98089.1; -; Genomic_DNA.
DR   EMBL; EF165008; ABM98090.1; -; Genomic_DNA.
DR   EMBL; EF165009; ABM98091.1; -; Genomic_DNA.
DR   EMBL; EF175456; ABM98092.1; -; Genomic_DNA.
DR   EMBL; EF175457; ABM98093.1; -; Genomic_DNA.
DR   EMBL; EF175458; ABM98094.1; -; Genomic_DNA.
DR   EMBL; EF175459; ABM98095.1; -; Genomic_DNA.
DR   EMBL; EF175460; ABM98096.1; -; Genomic_DNA.
DR   EMBL; EF379094; ABM92653.1; -; Genomic_DNA.
DR   EMBL; EF379095; ABM92654.1; -; Genomic_DNA.
DR   EMBL; EF492034; ABS30929.1; -; Genomic_DNA.
DR   EMBL; EF492035; ABS30930.1; -; Genomic_DNA.
DR   EMBL; EF492036; ABS30931.1; -; Genomic_DNA.
DR   EMBL; EF492037; ABS30932.1; -; Genomic_DNA.
DR   EMBL; EF492038; ABS30933.1; -; Genomic_DNA.
DR   EMBL; EF492039; ABS30934.1; -; Genomic_DNA.
DR   EMBL; EF492040; ABS30935.1; -; Genomic_DNA.
DR   EMBL; EF492041; ABS30936.1; -; Genomic_DNA.
DR   EMBL; EF492042; ABS30937.1; -; Genomic_DNA.
DR   EMBL; EF492043; ABS30938.1; -; Genomic_DNA.
DR   EMBL; EF492044; ABS30939.1; -; Genomic_DNA.
DR   EMBL; AH011562; AAM00023.1; -; Genomic_DNA.
DR   EMBL; AY083462; AAM00024.1; -; Genomic_DNA.
DR   CCDS; CCDS12903.1; -.
DR   SMR; Q8N743; -.
DR   IntAct; Q8N743; 22.
DR   STRING; 9606.ENSP00000291860; -.
DR   GlyGen; Q8N743; 3 sites.
DR   PhosphoSitePlus; Q8N743; -.
DR   BioMuta; KIR3DL3; -.
DR   DMDM; 269849611; -.
DR   jPOST; Q8N743; -.
DR   MassIVE; Q8N743; -.
DR   PaxDb; Q8N743; -.
DR   PeptideAtlas; Q8N743; -.
DR   PRIDE; Q8N743; -.
DR   ProteomicsDB; 72261; -.
DR   UCSC; uc032msg.2; human.
DR   GeneCards; KIR3DL3; -.
DR   HGNC; HGNC:16312; KIR3DL3.
DR   MIM; 610095; gene.
DR   neXtProt; NX_Q8N743; -.
DR   PharmGKB; PA134887375; -.
DR   eggNOG; ENOG502RU21; Eukaryota.
DR   InParanoid; Q8N743; -.
DR   PhylomeDB; Q8N743; -.
DR   TreeFam; TF352669; -.
DR   PathwayCommons; Q8N743; -.
DR   GeneWiki; KIR3DL3; -.
DR   Pharos; Q8N743; Tbio.
DR   PRO; PR:Q8N743; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q8N743; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 2.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00408; IGc2; 1.
DR   SUPFAM; SSF48726; SSF48726; 3.
PE   1: Evidence at protein level;
KW   Cell membrane; Disulfide bond; Glycoprotein; Immunoglobulin domain;
KW   Membrane; Polymorphism; Receptor; Reference proteome; Repeat; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..410
FT                   /note="Killer cell immunoglobulin-like receptor 3DL3"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000015091"
FT   TOPO_DOM        26..322
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        323..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        344..410
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          42..97
FT                   /note="Ig-like C2-type 1"
FT                   /evidence="ECO:0000305"
FT   DOMAIN          137..197
FT                   /note="Ig-like C2-type 2"
FT                   /evidence="ECO:0000305"
FT   DOMAIN          237..295
FT                   /note="Ig-like C2-type 3"
FT                   /evidence="ECO:0000305"
FT   CARBOHYD        179
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000305"
FT   CARBOHYD        239
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000305"
FT   CARBOHYD        273
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000305"
FT   DISULFID        49..95
FT                   /evidence="ECO:0000305"
FT   DISULFID        144..195
FT                   /evidence="ECO:0000250|UniProtKB:Q8NHL6"
FT   DISULFID        244..293
FT                   /evidence="ECO:0000250|UniProtKB:Q8NHL6"
FT   VARIANT         52
FT                   /note="R -> H (in allele KIR3DL3*00401, allele
FT                   KIR3DL3*00402, allele KIR3DL3*00801, allele KIR3DL3*00802
FT                   and allele KIR3DL3*026; dbSNP:rs113988102)"
FT                   /evidence="ECO:0000269|PubMed:11513144"
FT                   /id="VAR_060610"
FT   VARIANT         56
FT                   /note="N -> K (in allele KIR3DL3*00601, allele
FT                   KIR3DL3*00602, allele KIR3DL3*01501 and allele
FT                   KIR3DL3*01601; dbSNP:rs2075731)"
FT                   /id="VAR_060611"
FT   VARIANT         77
FT                   /note="R -> W (in allele KIR3DL3*010 and allele
FT                   KIR3DL3*028; dbSNP:rs202170060)"
FT                   /id="VAR_060612"
FT   VARIANT         149
FT                   /note="R -> S (in allele KIR3DL3*00601, allele
FT                   KIR3DL3*00602, allele KIR3DL3*01501 and allele
FT                   KIR3DL3*01601; dbSNP:rs62132665)"
FT                   /id="VAR_060613"
FT   VARIANT         152
FT                   /note="R -> H (in allele KIR3DL3*007, allele KIR3DL3*030
FT                   and allele KIR3DL3*031; dbSNP:rs199609975)"
FT                   /id="VAR_060614"
FT   VARIANT         168
FT                   /note="V -> I (in allele KIR3DL3*00101, allele
FT                   KIR3DL3*00102, allele KIR3DL3*00103, allele
FT                   KIR3DL3*0030101, allele KIR3DL3*00901, allele
FT                   KIR3DL3*00902, allele KIR3DL3*010 and allele KIR3DL3*028;
FT                   dbSNP:rs270790)"
FT                   /evidence="ECO:0000269|PubMed:9862332"
FT                   /id="VAR_019426"
FT   VARIANT         231
FT                   /note="G -> D (in allele KIR3DL3*005; dbSNP:rs112412050)"
FT                   /id="VAR_060615"
FT   VARIANT         290
FT                   /note="N -> T (in allele KIR3DL3*00601, allele
FT                   KIR3DL3*00602, allele KIR3DL3*01101, allele KIR3DL3*01102,
FT                   allele KIR3DL3*01501, allele KIR3DL3*01601 and allele
FT                   KIR3DL3*017; dbSNP:rs2302422)"
FT                   /evidence="ECO:0000269|PubMed:11960306"
FT                   /id="VAR_060616"
FT   VARIANT         321
FT                   /note="H -> N (in allele KIR3DL3*00101, allele
FT                   KIR3DL3*00102, allele KIR3DL3*00103, allele KIR3DL3*00601,
FT                   allele KIR3DL3*00602, allele KIR3DL3*01302, allele
FT                   KIR3DL3*01305, allele KIR3DL3*01306, allele KIR3DL3*01307,
FT                   allele KIR3DL3*017 and allele KIR3DL3*026; dbSNP:rs602444)"
FT                   /evidence="ECO:0000269|PubMed:9862332"
FT                   /id="VAR_060617"
FT   VARIANT         321
FT                   /note="H -> Y (in allele KIR3DL3*00101, allele
FT                   KIR3DL3*0030101, allele KIR3DL3*00401, allele
FT                   KIR3DL3*00402, allele KIR3DL3*007, allele KIR3DL3*01404,
FT                   allele KIR3DL3*01405, allele KIR3DL3*01601 and allele
FT                   KIR3DL3*028; dbSNP:rs602444)"
FT                   /evidence="ECO:0000269|PubMed:11513144"
FT                   /id="VAR_060618"
FT   VARIANT         324
FT                   /note="V -> A (in allele KIR3DL3*0030101, allele
FT                   KIR3DL3*00401, allele KIR3DL3*00402, allele KIR3DL3*007,
FT                   allele KIR3DL3*01404, allele KIR3DL3*01405, allele
FT                   KIR3DL3*01601 and allele KIR3DL3*028; dbSNP:rs662386)"
FT                   /id="VAR_060366"
FT   VARIANT         324
FT                   /note="V -> D (in allele KIR3DL3*029; dbSNP:rs662386)"
FT                   /id="VAR_060619"
FT   VARIANT         348
FT                   /note="A -> P (in allele KIR3DL3*027, allele KIR3DL3*029
FT                   and allele KIR3DL3*031; dbSNP:rs16985907)"
FT                   /id="VAR_056092"
FT   VARIANT         373
FT                   /note="E -> D (in allele KIR3DL3*027, allele KIR3DL3*029
FT                   and allele KIR3DL3*031; dbSNP:rs28504993)"
FT                   /id="VAR_060620"
SQ   SEQUENCE   410 AA;  44928 MW;  D1C4D06DE8FEF35E CRC64;
     MSLMVVSMAC VGFFLLEGPW PHVGGQDKPF LSAWPGTVVS EGQHVTLQCR SRLGFNEFSL
     SKEDGMPVPE LYNRIFRNSF LMGPVTPAHA GTYRCCSSHP HSPTGWSAPS NPVVIMVTGV
     HRKPSLLAHP GPLVKSGETV ILQCWSDVRF ERFLLHREGI TEDPLRLVGQ LHDAGSQVNY
     SMGPMTPALA GTYRCFGSVT HLPYELSAPS DPLDIVVVGL YGKPSLSAQP GPTVQAGENV
     TLSCSSRSLF DIYHLSREAE AGELRLTAVL RVNGTFQANF PLGPVTHGGN YRCFGSFRAL
     PHAWSDPSDP LPVSVTGNSR HLHVLIGTSV VIIPFAILLF FLLHRWCANK KNAVVMDQEP
     AGNRTVNRED SDEQDPQEVT YAQLNHCVFT QRKITRPSQR PKTPPTDTSV
//
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