ID KV6A3_MOUSE Reviewed; 107 AA.
AC P01677;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE RecName: Full=Ig kappa chain V-VI region TEPC 601/TEPC 191;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP PROTEIN SEQUENCE (TEPC 601).
RX PubMed=103573; DOI=10.1021/bi00618a035;
RA Rao D.N., Rudikoff S., Potter M.;
RT "Kappa chain variable regions from three galactan binding myeloma
RT proteins.";
RL Biochemistry 17:5555-5559(1978).
RN [2]
RP PROTEIN SEQUENCE (TEPC 191).
RX PubMed=6776525; DOI=10.1073/pnas.77.7.4270;
RA Rudikoff S., Rao D.N., Glaudemans C.P.J., Potter M.;
RT "Kappa chain joining segments and structural diversity of antibody
RT combining sites.";
RL Proc. Natl. Acad. Sci. U.S.A. 77:4270-4274(1980).
CC -!- MISCELLANEOUS: The two sequences are identical.
CC -!- MISCELLANEOUS: These chains were isolated from myeloma proteins that
CC bind galactan.
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DR AlphaFoldDB; P01677; -.
DR SMR; P01677; -.
DR MaxQB; P01677; -.
DR InParanoid; P01677; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P01677; Protein.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0006955; P:immune response; IBA:GO_Central.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR23267:SF201; IG KAPPA CHAIN V-IV REGION S107B-RELATED; 1.
DR PANTHER; PTHR23267; IMMUNOGLOBULIN LIGHT CHAIN; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW Adaptive immunity; Direct protein sequencing; Disulfide bond; Immunity;
KW Immunoglobulin; Reference proteome.
FT CHAIN 1..>107
FT /note="Ig kappa chain V-VI region TEPC 601/TEPC 191"
FT /id="PRO_0000059812"
FT REGION 1..23
FT /note="Framework-1"
FT REGION 24..33
FT /note="Complementarity-determining-1"
FT REGION 34..48
FT /note="Framework-2"
FT REGION 49..55
FT /note="Complementarity-determining-2"
FT REGION 56..87
FT /note="Framework-3"
FT REGION 88..96
FT /note="Complementarity-determining-3"
FT REGION 97..106
FT /note="Framework-4"
FT DISULFID 23..87
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT NON_TER 107
SQ SEQUENCE 107 AA; 11568 MW; 203CD752A5EC34D7 CRC64;
EIVLTQSPAI TAASLGQKVT ITCSASSSVS YMHWYQQKSG TSPKPWIYEI SKLASGVPAR
FSGSGSGTSY SLTISSMEAE DAAIYYCQQW NYPLITFGAG TKLELKR
//
