ID L0AMP0_NATGS Unreviewed; 228 AA.
AC L0AMP0;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Metal-dependent phosphoesterase, PHP family {ECO:0000313|EMBL:AFZ74724.1};
DE SubName: Full=PHP domain-containing protein {ECO:0000313|EMBL:ELY73469.1};
GN OrderedLocusNames=Natgr_3611 {ECO:0000313|EMBL:AFZ74724.1};
GN ORFNames=C490_01350 {ECO:0000313|EMBL:ELY73469.1}, CYV19_06820
GN {ECO:0000313|EMBL:PLK20999.1};
OS Natronobacterium gregoryi (strain ATCC 43098 / DSM 3393 / CCM 3738 / CIP
OS 104747 / IAM 13177 / JCM 8860 / NBRC 102187 / NCIMB 2189 / SP2).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronobacterium.
OX NCBI_TaxID=797304 {ECO:0000313|EMBL:AFZ74724.1, ECO:0000313|Proteomes:UP000010468};
RN [1] {ECO:0000313|Proteomes:UP000010468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43098 / CCM 3738 / NCIMB 2189 / SP2
RC {ECO:0000313|Proteomes:UP000010468};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sproer C.,
RA Anderson I., Woyke T.;
RT "Complete sequence of Natronobacterium gregoryi SP2.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFZ74724.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SP2 {ECO:0000313|EMBL:AFZ74724.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sproer C.,
RA Anderson I., Woyke T.;
RT "Complete sequence of Natronobacterium gregoryi SP2.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ELY73469.1, ECO:0000313|Proteomes:UP000011613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP2 {ECO:0000313|EMBL:ELY73469.1,
RC ECO:0000313|Proteomes:UP000011613};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
RN [4] {ECO:0000313|EMBL:PLK20999.1, ECO:0000313|Proteomes:UP000234484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP2 {ECO:0000313|EMBL:PLK20999.1,
RC ECO:0000313|Proteomes:UP000234484};
RC TISSUE=Freeze-dried powder thallus {ECO:0000313|EMBL:PLK20999.1};
RA Jiang L., He B., Kang J., Yu M., Li N., Fang Y., Tang Z., Wu P., Yao P.,
RA Huang J.;
RT "The characterization of oligonucleotides binding to NgAgo.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003377; AFZ74724.1; -; Genomic_DNA.
DR EMBL; AOIC01000013; ELY73469.1; -; Genomic_DNA.
DR EMBL; PKKI01000015; PLK20999.1; -; Genomic_DNA.
DR RefSeq; WP_005575844.1; NZ_PKKI01000015.1.
DR AlphaFoldDB; L0AMP0; -.
DR STRING; 797304.Natgr_3611; -.
DR GeneID; 14209801; -.
DR KEGG; nge:Natgr_3611; -.
DR PATRIC; fig|797304.7.peg.271; -.
DR eggNOG; arCOG00302; Archaea.
DR HOGENOM; CLU_072983_3_0_2; -.
DR Proteomes; UP000010468; Chromosome.
DR Proteomes; UP000011613; Unassembled WGS sequence.
DR Proteomes; UP000234484; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07432; PHP_HisPPase; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR004013; PHP_dom.
DR InterPro; IPR003141; Pol/His_phosphatase_N.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR NCBIfam; NF038032; CehA_McbA_metalo; 1.
DR PANTHER; PTHR42924; EXONUCLEASE; 1.
DR PANTHER; PTHR42924:SF3; POLIIIAC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02811; PHP; 1.
DR Pfam; PF13263; PHP_C; 1.
DR SMART; SM00481; POLIIIAc; 1.
DR SUPFAM; SSF89550; PHP domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010468}.
FT DOMAIN 4..70
FT /note="Polymerase/histidinol phosphatase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00481"
SQ SEQUENCE 228 AA; 24543 MW; 9DD88AE3E9D53575 CRC64;
MLSVELHAHS SLSYDGRDPV ELILEQAEAV GLDAIAITDH DEIDASLEAA ERAPEYGLVG
IPGIEISSKA GHVLGLGVEE AIPPGLSFET TIEEIHAQGG LAVVPHPFQE SRHGVMARIS
REQLANGDAI EVYNSRLLTG RANRQAERFA QSRNLPMTAG SDAHISEMVG QAVTRVDAEE
RSAAAILEAI EQGRTSVEGK RTPWHISFRQ FAGGVTRRIR SSVLGVIR
//
