ID L0AN00_NATGS Unreviewed; 270 AA.
AC L0AN00;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=CRISPR-associated protein Cas5, Hmari subtype {ECO:0000313|EMBL:ELY72599.1};
DE SubName: Full=CRISPR-associated protein Cas5, subtype I-B/HMARI {ECO:0000313|EMBL:AFZ74577.1};
DE SubName: Full=Type I-B CRISPR-associated protein Cas5 {ECO:0000313|EMBL:PLK21681.1};
GN Name=cas5b {ECO:0000313|EMBL:PLK21681.1};
GN OrderedLocusNames=Natgr_3458 {ECO:0000313|EMBL:AFZ74577.1};
GN ORFNames=C490_03383 {ECO:0000313|EMBL:ELY72599.1}, CYV19_02270
GN {ECO:0000313|EMBL:PLK21681.1};
OS Natronobacterium gregoryi (strain ATCC 43098 / DSM 3393 / CCM 3738 / CIP
OS 104747 / IAM 13177 / JCM 8860 / NBRC 102187 / NCIMB 2189 / SP2).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronobacterium.
OX NCBI_TaxID=797304 {ECO:0000313|EMBL:AFZ74577.1, ECO:0000313|Proteomes:UP000010468};
RN [1] {ECO:0000313|Proteomes:UP000010468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43098 / CCM 3738 / NCIMB 2189 / SP2
RC {ECO:0000313|Proteomes:UP000010468};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sproer C.,
RA Anderson I., Woyke T.;
RT "Complete sequence of Natronobacterium gregoryi SP2.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFZ74577.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SP2 {ECO:0000313|EMBL:AFZ74577.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sproer C.,
RA Anderson I., Woyke T.;
RT "Complete sequence of Natronobacterium gregoryi SP2.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ELY72599.1, ECO:0000313|Proteomes:UP000011613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP2 {ECO:0000313|EMBL:ELY72599.1,
RC ECO:0000313|Proteomes:UP000011613};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
RN [4] {ECO:0000313|EMBL:PLK21681.1, ECO:0000313|Proteomes:UP000234484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP2 {ECO:0000313|EMBL:PLK21681.1,
RC ECO:0000313|Proteomes:UP000234484};
RC TISSUE=Freeze-dried powder thallus {ECO:0000313|EMBL:PLK21681.1};
RA Jiang L., He B., Kang J., Yu M., Li N., Fang Y., Tang Z., Wu P., Yao P.,
RA Huang J.;
RT "The characterization of oligonucleotides binding to NgAgo.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003377; AFZ74577.1; -; Genomic_DNA.
DR EMBL; AOIC01000025; ELY72599.1; -; Genomic_DNA.
DR EMBL; PKKI01000005; PLK21681.1; -; Genomic_DNA.
DR RefSeq; WP_005576674.1; NZ_PKKI01000005.1.
DR AlphaFoldDB; L0AN00; -.
DR STRING; 797304.Natgr_3458; -.
DR GeneID; 14209486; -.
DR KEGG; nge:Natgr_3458; -.
DR PATRIC; fig|797304.7.peg.663; -.
DR eggNOG; arCOG02758; Archaea.
DR HOGENOM; CLU_090888_0_0_2; -.
DR Proteomes; UP000010468; Chromosome.
DR Proteomes; UP000011613; Unassembled WGS sequence.
DR Proteomes; UP000234484; Unassembled WGS sequence.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR GO; GO:0043571; P:maintenance of CRISPR repeat elements; IEA:InterPro.
DR Gene3D; 3.30.70.2660; -; 1.
DR InterPro; IPR021124; CRISPR-assoc_prot_Cas5.
DR InterPro; IPR013421; CRISPR-assoc_prot_Cas5_HALMA.
DR InterPro; IPR013422; CRISPR-assoc_prot_Cas5_N.
DR NCBIfam; TIGR02592; cas_Cas5h; 1.
DR NCBIfam; TIGR02593; CRISPR_cas5; 1.
DR Pfam; PF09704; Cas_Cas5d; 1.
PE 4: Predicted;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Reference proteome {ECO:0000313|Proteomes:UP000010468}.
SQ SEQUENCE 270 AA; 29941 MW; A9778DE0E2BB4212 CRC64;
MGQQSLDAWE HDEGDSAFPE RCLSVTVRGP WGHFRRIEGN VVKQTYRIIP RTTVAGLFAA
VLGIERDGYY ELFGPNRSAI AIEPVREIRT INMPMNTLST ADGDLQSLNG RGKLSVKLPD
PTTLRQQHNY EVLVEPAYRI DVALADEERY RELRSMLEDG RSHYVPSLGL SEHLAELEYH
GEFDIGPGPK ATADDQPVAV DSAVPDAVEN VVFEAGTRCQ VEESPAFMTT DPGGRTTTEF
TAYTYNPDAE PLRIRDVDAA TVDGRTVVFV
//
