ID   L0DHJ6_SINAD            Unreviewed;       357 AA.
AC   L0DHJ6;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Nucleoside-diphosphate-sugar epimerase {ECO:0000313|EMBL:AGA28156.1};
GN   OrderedLocusNames=Sinac_3928 {ECO:0000313|EMBL:AGA28156.1};
OS   Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 /
OS   MOB10).
OC   Bacteria; Planctomycetota; Planctomycetia; Isosphaerales; Isosphaeraceae;
OC   Singulisphaera.
OX   NCBI_TaxID=886293 {ECO:0000313|EMBL:AGA28156.1, ECO:0000313|Proteomes:UP000010798};
RN   [1] {ECO:0000313|EMBL:AGA28156.1, ECO:0000313|Proteomes:UP000010798}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10
RC   {ECO:0000313|Proteomes:UP000010798};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Chertkov O.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA   Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA   Woyke T., Wu D., Tindall B., Pomrenke H., Brambilla E., Klenk H.-P.,
RA   Eisen J.A.;
RT   "Complete sequence of chromosome of Singulisphaera acidiphila DSM 18658.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC         Evidence={ECO:0000256|ARBA:ARBA00001911};
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DR   EMBL; CP003364; AGA28156.1; -; Genomic_DNA.
DR   RefSeq; WP_015247288.1; NZ_JH621484.1.
DR   AlphaFoldDB; L0DHJ6; -.
DR   STRING; 886293.Sinac_3928; -.
DR   KEGG; saci:Sinac_3928; -.
DR   eggNOG; COG0451; Bacteria.
DR   HOGENOM; CLU_007383_4_0_0; -.
DR   OrthoDB; 258549at2; -.
DR   Proteomes; UP000010798; Chromosome.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0048040; F:UDP-glucuronate decarboxylase activity; IEA:InterPro.
DR   GO; GO:0042732; P:D-xylose metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR044516; UXS.
DR   PANTHER; PTHR43078:SF6; UDP-GLUCURONIC ACID DECARBOXYLASE 1; 1.
DR   PANTHER; PTHR43078; UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010798}.
FT   DOMAIN          29..273
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   357 AA;  38572 MW;  28AEF3F87460C8DF CRC64;
     MANPLADDLD HVLAQVDPLW EDLRGARLFL TGGTGFFGCW LLESLLWADA HRRLGVEVVV
     LTRSPAAFAR KAPHLAGHRA VRLYEGDVRS FADPEGTFTH VIHAATEASA ALNAEAPRIM
     FETIVEGTRR TLDLARRSGA SRFLLTSSGA VYGSQPATLT HVGEDYPGAP DPTDPRSAYG
     EGKRVAEHLA ALECHAHGLG AVIARCFAFV GPYLPLDIHF AVGNFVRDAL AGGPVRVAGD
     GTPWRSYQYA ADLMVWLWSI LLRGVPGRSY NVGSEEALTI GDVARRIAEA EGVAWGIDRE
     PIAGALATRY VPSTARARDE LGLACPIGFD DAIARTVRWH RNRIRNLVDC PSPSLVP
//