ID L0DSK6_THIND Unreviewed; 1044 AA.
AC L0DSK6;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=RND multidrug efflux transporter Acriflavin resistance protein {ECO:0000313|EMBL:AGA31988.1};
GN Name=acrD [C] {ECO:0000313|EMBL:AGA31988.1};
GN OrderedLocusNames=TVNIR_0277 {ECO:0000313|EMBL:AGA31988.1};
OS Thioalkalivibrio nitratireducens (strain DSM 14787 / UNIQEM 213 / ALEN2).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Thioalkalivibrio.
OX NCBI_TaxID=1255043 {ECO:0000313|EMBL:AGA31988.1, ECO:0000313|Proteomes:UP000010809};
RN [1] {ECO:0000313|Proteomes:UP000010809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14787 / UNIQEM 213 / ALEN2
RC {ECO:0000313|Proteomes:UP000010809};
RA Tikhonova T.V., Pavlov A.R., Beletsky A.V., Mardanov A.V., Sorokin D.Y.,
RA Ravin N.V., Popov V.O.;
RT "Complete sequence of Thioalkalivibrio nitratireducens.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003989; AGA31988.1; -; Genomic_DNA.
DR RefSeq; WP_015257143.1; NC_019902.2.
DR AlphaFoldDB; L0DSK6; -.
DR STRING; 1255043.TVNIR_0277; -.
DR KEGG; tni:TVNIR_0277; -.
DR PATRIC; fig|1255043.3.peg.278; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_6; -.
DR OrthoDB; 9758297at2; -.
DR Proteomes; UP000010809; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF14; BLL4319 PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 855..875
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 882..902
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 908..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 954..973
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 985..1011
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1044 AA; 114054 MW; D5A3ECE20C642270 CRC64;
MIISDIANRR PVLAVVFNLL LVTFGLIAYQ QLPLREYPDV DAPVVTVQTG YPGASAEIIE
REVTQRLEDR IAGIEGIRYI ESSSRDGRSS ITIEFNLNRD IDGAANDIRE AVSRVIRFLP
DEVDPPQVTK ADADASPILW LNLSSTTMDG LELADYARRY LVDRLSVVDG VALIRLGGAK
RYAMRIWVDR EALAARGLTV ADIEDALRRE NVELPAGRID SLDREFKVRV DRMYRTAEDF
AGLVIQRADN QHLVRLGEVA EVAVGSDSER TEFRGNGEDM VGLGIIRQAN ANVLDVANGA
KRVAAELQEQ LPDGTSLVVT YDSSVFIEGA IREVYITLAI ATAAVVLVIY LFLGSWRATL
IPGVTVPVAI TAAFIGISLL GFSVNLLTLL ALVLAIGLVV DDAIVMLENI HRRIERGEPG
LLAAYRGARQ VGFAIVATTS VLVAVFVPLA FLSGTVGRLF TEFALAIAIA VVFSSLVALT
LAPVLSGRLM HKGDDETGMA RIIGRGFGAL ERGYARLLQR SLPYSWGVVP ILLLSLGGAW
WLLNEIPDEF APREDRGAFF VLVNGPEGAS FEYMREQMAE VERRMLPLTE QGEVRRILVR
TPRAFGNTEV VNNGFVIVIM HHWNDRERLS WEVMEDINAS LAEIPGIQSR LVMRQGLSRG
RIGQPVQFVI TGPDYDELAE WGQTLLERAE EIPGLARLDL DYKPTQPQVT VRIDRDRAAD
LGVSLATVGR TLDVMLGGRA VTTYIDRGEE YDVIIEGRSD QRRTPGDISN LYVRSDSGEL
IPLSSLVSYQ EVAGAGSLER YNRARSVTLS AAVQEGYTLG QVLAALDAAA DEVLPPEARI
DYKGESLDLR EGSQAVFFTF VLALVIVYLV LAAQFESFVH PFVIMLTVPL AVVGALLGLY
LTGQTINIYS QIGMVMLIGL AAKNGILIVE FANQLRDHGR EFSHAVVEAA SMRLRPVLMT
ALTTVAGSIP LILATGPGAE TRFVIGIAVF SGVLFATLFT LFVIPASYGL LARQTTSPKA
MTRRIEQLDS RIDDVDRGRE GGVA
//
