ID   L0EAC5_THECK            Unreviewed;       597 AA.
AC   L0EAC5;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Putative signal transduction protein with a C-terminal ATPase domain {ECO:0000313|EMBL:AGA56599.1};
GN   OrderedLocusNames=Theco_0374 {ECO:0000313|EMBL:AGA56599.1};
OS   Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Thermobacillus.
OX   NCBI_TaxID=717605 {ECO:0000313|EMBL:AGA56599.1, ECO:0000313|Proteomes:UP000010795};
RN   [1] {ECO:0000313|Proteomes:UP000010795}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18247 / JCM 13945 / KWC4
RC   {ECO:0000313|Proteomes:UP000010795};
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Anderson I.,
RA   Woyke T.;
RT   "Complete sequence of chromosome of Thermobacillus composti KWC4.";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP003255; AGA56599.1; -; Genomic_DNA.
DR   RefSeq; WP_015253363.1; NC_019897.1.
DR   AlphaFoldDB; L0EAC5; -.
DR   STRING; 717605.Theco_0374; -.
DR   KEGG; tco:Theco_0374; -.
DR   eggNOG; COG2972; Bacteria.
DR   HOGENOM; CLU_020473_6_0_9; -.
DR   OrthoDB; 9776552at2; -.
DR   Proteomes; UP000010795; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010795};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        300..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          321..373
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   COILED          361..388
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   597 AA;  67413 MW;  E26F84CA36949A62 CRC64;
     MRKWLNRFQI NGLFIKLFLV TVISIAAVSV LVTWSTIRLS ERLFIDTFSI INSKVLSQIN
     SGFQSLNTAI VTASNNMLQS GSVKQYLTES DGDSLTMAKS YYNMRKQMDQ IATAIETYET
     AIIVKGINGR TYMTNRLIWP IAEADIDRHP VTLAAHEDPK RLLYLADFRE ADGAEPVIIA
     AKAMMERSTG FVYGTLFFAM RESEFKQLYS SYTSEGNDMV ILDRSGTILS SNRGELIGRQ
     VPELLGIAED MHGHGRDYAS MHLFGRNQIV LAEYLPFYDL YMVNLIDKQS ILNTLVDTRT
     ITLIVIGIVA GALIIVYMIS RRLTRSLTRL VKQISNISKY EFGHYVSETG SYETRQLARA
     FNFMLDELKE YLAELDQAQR KKRNAELAAL QRQINPHFLY NTLASIKIMV KQGSREKASE
     TINALIALLQ NAIGDVSETI TVERDIELLR HYALIMEARN GDRIKLHDFV APDCRDALVP
     KLMIQPFVEN AFFHAFNRKA EGSVYVTVSR KGNTLVCEIV DNGDGMELDG GWPESKSRSR
     GHLFTGIGMR NVHERLTLLY GEPYGVQIQS RAGEGTTVRI ELPYRTAKNI PSIQKSS
//